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1
tesis de grado
En el presente trabajo académico se plasma un Plan de Cuidados de Enfermería para la atención de un recién nacido con diagnóstico médico de sepsis neonatal, con el objetivo de contribuir a recuperar la salud del neonato aplicando un cuidado basado en evidencias y sustentado en bases científicas, dentro del mismo se plantea la educación a la madre del neonato para que sea partícipe en el cuidado de su niño
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Objective: To determine the clinical-epidemiological characteristics of newborns with early-onset neonatal sepsis in a public hospital in Lima, Peru, 2016-2017. Materials and methods: An observational, retrospective study of 303 newborns born in Hospital Nacional Dos de Mayo, diagnosed with early-onset neonatal sepsis (2016-2017) and with complete medical records. Maternal variables: age, education, marital status, prenatal care, PROM, type of delivery, UTI, chorioamnionitis, anemia; neonatal variables: sex, gestational age, weight, Apgar, clinical signs, hemoculture, isolated organism, treatment, antibiotic sensitivity. Data processed in Excel and analyzed in SPSS Statistics V25. The incidence of early-onset neonatal sepsis was determined. Results: Incidence of early-onset neonatal sepsis: 67.08/1,000 (2016) and 127.85/1,000 (2017) live births. Incidence of confirmed early-onset neonata...
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Introduction. Neonatal sepsis is a set of clinical signs and symptoms caused by a systemic infection, associated with maternal, neonatal or hospital risk factors. Objective. Provide informed recommendations for the best available evidence for the prevention, diagnosis and treatment of neonatal sepsis. Methods an Evidence-based Clinical Practice Guide (CPG) was developed through an adaptation process, in charge of a team of methodologists and neonatologists who are experts in the clinical management of neonatal sepsis. The search and pre-selection of CPGs that respond to the scope and objectives set were carried out, using the AGREE-II instrument, the methodological quality of the guides was evaluated and their adaptation decided. To identify the evidence that answers the questions in the guideline, a systematic search was carried out in multiple databases: M...
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La sepsis grave y el shock por sepsis constituyen un importante problema de salud como resultado de la lesión generada por la respuesta inmunológica de la persona a una infección grave1 ; esta se define como sepsis con disfunción orgánica, hipotensión e hipoperfusión la cual al evolucionara sin tratamiento adecuado y oportuno puede llevar al choque séptico y posteriormente la muerte2. Según las estadísticas de EsSalud e la primera causa de ingreso a cuidados intensivos de origen infeccioso en razón a lo cual se realizan cuidados interdisciplinarios que de acuerdo con la campana mundial de supervivencia a la Sepsis3, requieren de su identificación temprana, atención inmediata buscando el restablecimiento de la homeostasis del paciente. El presente caso ilustra el proceso de valoración, diagnóstico e intervenciones de enfermería así como los criterios de resultado que se u...
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tesis de grado
Introduction: The production of lactate is a result of cellular processes and its increase is a consequence, among other causes, of hypo perfusion of the tissues. Regardless of the mechanism, it has been observed in several studies that increased serum lactate increased to the patients’ admission is associated with a worse prognosis and mortality. Objective: To determine the usefulness of serum lactate as a predictor of mortality in critically ill patients with severe sepsis and septic shock Materials and Methods: Cases and controls study. A total of 182 patients admitted to the ICU during the period 2011-2016 with a diagnosis of severe sepsis and septic shock were studied divided in 91 cases (deceased) and 91 controls (survivors). The value of serum lactate was determined and the odds ratio (OR) was found. The exposed group consisted of patients with lactate level (> = 2mmol / L).The ...
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Sepsis is considered a public health problem because severe infections still are a major cause of death worldwide. Within the comprehensive management of the patient with severe sepsis or septic shock, the early administration of an appropriate antimicrobial regimen is one of the key strategies for survival and for reducing morbidity and mortality. In this review, we describe the antimicrobial therapy for the following conditions: severe pneumonia, urosepsis, intra-abdominal infections, serious skin and soft tissue infections, bacterial meningitis, fungal sepsis, venous catheter-related infections, and sepsis of undetermined origin. It is necessary for physicians who take care of patients with serious infections, that they must know not only the clinical manifestations of each process, but also their epidemiological characteristics, local bacterial prevalence, resistance patterns and pha...
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tesis de grado
Determinar la fuerza asociación de la Proteína C Reactiva, Ferritina, Procalcitonina y Lactato, como predictores de disfunción multiorgánica en niños con sepsis. Material y métodos: Se realizó un estudio observacional analítico de cohorte retrospectivo en niños entre 6 meses a 15 años con diagnóstico de sepsis y que cuenten con medición de Ferritina, Proteína C Reactiva, Procalcitonina y Lactato dentro de las 48 horas de ingresados. El tamaño de la muestra y la población coincidieron. Se analizó la relación entre la elevación de los marcadores y la disfunción multiorgánica. Se recopilaron datos en fichas de recolección, se realizó un análisis estadístico con la prueba de Mc Nemar y de los indicadores de discriminación pronóstica y el nivel de significancia p < 0.05. Se utilizó el programa estadístico SPSS-26 para el procesamiento. Resultados: Solo la Ferritina...
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Objective: Determine degree of adherence to the Clinical Practice Guidelines for Attention of Obstetric Emergencies (hypertensive, hemorrhagic and sepsis disorders) in maternal deaths occurred at the Carlos Monge Medrano Hospital (HCMM) of Juliaca in 2020. Method: Quantitative, descriptive, retrospective, observational and cross-sectional study. Medical records of all maternal deaths in HCMM in 2020 were reviewed, using instrument for the evaluation of adherence to Clinical Practice Guidelines (CPG), previously validated, based on an instrument of the Mexican Institute of Social Security, adapting it to CPG recommendations of Ministry of Health of Peru. (Degree of agreement between judges 97.1%). The database was prepared in Excel, processed, and analyzed in SPSS version 27.0. Results: Of the 7 clinical histories of maternal death, it was found in general low and medium adherence to CPG,...
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Objective: Determine degree of adherence to the Clinical Practice Guidelines for Attention of Obstetric Emergencies (hypertensive, hemorrhagic and sepsis disorders) in maternal deaths occurred at the Carlos Monge Medrano Hospital (HCMM) of Juliaca in 2020. Method: Quantitative, descriptive, retrospective, observational and cross-sectional study. Medical records of all maternal deaths in HCMM in 2020 were reviewed, using instrument for the evaluation of adherence to Clinical Practice Guidelines (CPG), previously validated, based on an instrument of the Mexican Institute of Social Security, adapting it to CPG recommendations of Ministry of Health of Peru. (Degree of agreement between judges 97.1%). The database was prepared in Excel, processed, and analyzed in SPSS version 27.0. Results: Of the 7 clinical histories of maternal death, it was found in general low and medium adherence to CPG,...
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artículo
Sepsis is considered a public health problem because severe infections still are a major cause of death worldwide. Within the comprehensive management of the patient with severe sepsis or septic shock, the early administration of an appropriate antimicrobial regimen is one of the key strategies for survival and for reducing morbidity and mortality. In this review, we describe the antimicrobial therapy for the following conditions: severe pneumonia, urosepsis, intra-abdominal infections, serious skin and soft tissue infections, bacterial meningitis, fungal sepsis, venous catheter-related infections, and sepsis of undetermined origin. It is necessary for physicians who take care of patients with serious infections, that they must know not only the clinical manifestations of each process, but also their epidemiological characteristics, local bacterial prevalence, resistance patterns and pha...
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tesis de grado
El objetivo principal de este caso clínico es realizar un plan de cuidado del paciente basado en la valoración, con diagnostico celulitis facial, En donde se elaboró un proceso de atención de enfermería y a la vez obtener el bienestar y atención adecuada del paciente el cual estuvo internado en el Hospital San Juan de Lurigancho. Materiales y métodos: este estudio es tipo descriptivo, de diseño no experimental y transversal se realizó mediante el proceso de atención de enfermería en un caso clínico, utilizando el formato de valoración por patrones de Marjory Gordon, NANDA, NOC Y NIC, los cuales serán plasmadas en las tablas e interpretadas según nuestro criterio para un eficaz resultado basando en evidencia. Resultados: en el análisis del diagnóstico de enfermería hipertermia, en la figura 1 se puede analizar que las intervenciones que se llevó a cabo fueron ejecutadas...
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Se presentan 21 casos de gangrena de pulmón, atendidos en el Hospital Regional de Vinnitsa, Ucrania N.I. Pirogov, Rusia, entre enero 1985 y marzo 1990. Presentamos la condición clínica de los pacientes considerando grado de intoxicación séptica, presencia de enfermedades concomitantes graves, insuficiencia de órganos vitales, complicaciones así como la extensión del proceso patológico Se analiza también los métodos terapéuticos que incluyen punción percutánea del pulmón con administración local de antibióticos, broncoscopías terapéuticas, microtraqueostomía con caracterización de tráquea, drenaje de cavidad pleural, terapia de desintoxicación, terapia inmunológica, estimulación de las defensas. Además, se revisan las condiciones de alta de los pacientes y la mortalidad. Se discute la eficacia de administración de antibióticos al foco infeccioso, el empleo de m...
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tesis de grado
Determinar si la obesidad materna pregestacional es factor de riesgo para desarrollar complicaciones en el recién nacido a término en el Hospital Apoyo II-2 Sullana durante el año 2023. Materiales y métodos: Estudio tipo cohorte retrospectiva, realizado a 180 gestantes con obesidad pregestacional en el Hospital Apoyo II-2 Sullana durante el 2023. Mediante un muestreo probabilístico aleatorio simple se dividirá en dos grupos, el grupo de expuestos estará integrado por 60 gestantes obesas y el grupo de no expuestos estará constituido por 120 gestantes no obesas. Todos los datos serán recogidos del “Centro Latinoamericano de Perinatología” (CLAP) y de las respectivas historias clínicas, las cuales serán procesadas en la hoja de recolección de datos diseñada específicamente para este proyecto y se tabulará los resultados para obtener el Risk Ratio. Resultados: El 48.33% d...
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Objective: Identify neonatal pathologies or conditions that influence the prolongation of hospital stay in a Neonatal Intensive Care Unit (NICU). Materials and methods: An observational, retrospective, case-control study was carried out; in neonates hospitalized in the NICU, during the period 2015-2019, considering their perinatal and postnatal diagnoses as factors to be evaluated, as well as hospital stay. Two groups were divided: cases (prolonged stay) and controls (non-prolonged stay). The collected data were processed in the SPSS v.23 program, obtaining the OR and the Binary Logistic Regression. Results: 361 neonates (91 cases and 270 controls) were included, finding significance in perinatal factors (p<0.05): Birth weight (1000g to <1500g, ORa 8.2: CI3.1 - 21.2) and gestational age (28 to 31 weeks , ORa 18.6: CI4.8-71.4; 32-33 weeks, ORa 8.1: CI3.5 – 18.4); and postnatal fac...
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Introduction: Peritonitis is an inflammatory process of multiple etiologies that can compromise the patient's life, so it is necessary to understand the risk factors that are associated with poor clinical evolution. Objectives: To determine the factors associated with poor clinical evolution in adult patients hospitalized for peritonitis in the Emergency Hospital "José Casimiro Ulloa, 2012 - 2016". Methods: Analytical, retrospective study, of type cases and controls. The universe population of the cases will be conformed by all the patients with bad evolution (patients with a hospital stay greater than 9 days). The universe population for the control group consisted of patients with peritonitis with favorable evolution (patients with a hospital stay of less than 9 days) hospitalized for peritonitis. The descriptive and analytical analysis was done with chi square and logistic regression...
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Introduction: Peritonitis is an inflammatory process of multiple etiologies that can compromise the patient's life, so it is necessary to understand the risk factors that are associated with poor clinical evolution. Objectives: To determine the factors associated with poor clinical evolution in adult patients hospitalized for peritonitis in the Emergency Hospital "José Casimiro Ulloa, 2012 - 2016". Methods: Analytical, retrospective study, of type cases and controls. The universe population of the cases will be conformed by all the patients with bad evolution (patients with a hospital stay greater than 9 days). The universe population for the control group consisted of patients with peritonitis with favorable evolution (patients with a hospital stay of less than 9 days) hospitalized for peritonitis. The descriptive and analytical analysis was done with chi square and logistic regression...
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Preeclampsia is a condition that affects pregnant women and is one of the leading causes of maternal death in Peru and the world, causing morbidity in both the mother and her newbom, in the most common problems in the neonatal age that associated with this pathology in neonates are: intrauterine growth restriction, small for gestational age, low birth weight, prematurity, metabolic disorders, clotting disorders, intraventricular hemorrhage, hyperbilirubinemia, respiratory distress, patent ductus arteriosus, necrotizing enterocolitis, hypotension, retinopathy , erosive gastritis, predisposition to infectious processes, including sepsis due to deficit in the activity of granulocyte chemotaxis and cytokines, etc. The impact of this disease continues throughout the life associating risk of diabetes mellitus, hyperlipidemia, hypertension, coronary artery disease, among others.
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Preeclampsia is a condition that affects pregnant women and is one of the leading causes of maternal death in Peru and the world, causing morbidity in both the mother and her newbom, in the most common problems in the neonatal age that associated with this pathology in neonates are: intrauterine growth restriction, small for gestational age, low birth weight, prematurity, metabolic disorders, clotting disorders, intraventricular hemorrhage, hyperbilirubinemia, respiratory distress, patent ductus arteriosus, necrotizing enterocolitis, hypotension, retinopathy , erosive gastritis, predisposition to infectious processes, including sepsis due to deficit in the activity of granulocyte chemotaxis and cytokines, etc. The impact of this disease continues throughout the life associating risk of diabetes mellitus, hyperlipidemia, hypertension, coronary artery disease, among others.
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tesis de grado
Introducción: La colangitis aguda se define como inflamación producto de una infección en los conductos biliares, caracterizada por un proceso inflamatorio e infeccioso que compromete todo el organismo y generalmente requiere atención inmediata debido a su potencial riesgo vital. Es considerada como una de las complicaciones más graves de la obstrucción de la vía biliar principal. La colangitis presenta una amplia variedad de manifestaciones clínicas. En el 23% de los casos, los pacientes son asintomáticos, y el diagnóstico solo se realiza cuando aparecen complicaciones o hallazgos específicos. Alrededor del 45% de los casos inician con síntomas leves, pero la progresión de la enfermedad puede derivar en sepsis grave y potencialmente mortal. Objetivo. Determinar las características clínicas y quirúrgicas de los pacientes con colangitis aguda tratados en el Hospital Region...
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The Cardio-Renal Syndrome (CRS) is a multi-organ disease process characterized by joint cardiac, renal, and vascular systems dysfunction magnified by abnormal "cross talk" between body systems which are necessary for optimal equilibrium and functioning of the whole organism. There are five phenotypes:  type-1 (Acute Cardio-Renal); type-2 (Chronic Cardio-Renal); type-3 (Acute Reno-Cardiac); type 4 (Chronic Cardio-Renal); type-5 (Secondary Cardio-Renal). Type-1 is the most common type (50% of cases). Acute heart failure decreases cardiac output and reduces renal blood flow, effective glomerular perfusion, filtration pressure, and glomerular filtration rate. Type-2 is the second most common (20% of cases). Chronic heart failure results in chronic hypoperfusion which causes/aggravates chronic kidney disease. In Type-3, acute kidney injury causing volume overload which triggers acute hea...