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1
tesis doctoral
Mycobacterium tuberculosis (Mtb) sigue siendo uno de los patógenos más mortales a nivel mundial, a pesar de ser una enfermedad prevenible. La tuberculosis (TB) se trata con una combinación de cuatro medicamentos antituberculosos de primera línea: rifampicina (RIF), isoniacida, pirazinamida y etambutol, para cepas sensibles a los medicamentos. Entre estos, la RIF es uno de los agentes más potentes para controlar la enfermedad. Sin embargo, la resistencia a la RIF conlleva la aparición de casos de TB resistente a la RIF (RR-TB) o multidrogo resistente (MDR-TB). El mecanismo principal de resistencia implica mutaciones en el gen rpoB, que es responsable de aproximadamente el 95% de los casos. No obstante, todavía se están identificando otros mecanismos moleculares y condiciones que podrían contribuir a la propagación de las poblaciones RR-TB y MDR-TB. Esta investigación doctoral s...
2
artículo
The purpose of the study was to test the effectiveness of the application of the first and second derivatives to analyze the mathematical functions in future teachers of Mathematics and Physics at UNHEVAL; for this, a cause-effect study and quasi-experimental design was carried out, hoping to optimize the learning of functions in a graphical and analytical way, by means of the exact location of the maximum and minimum points, inflection, determination of the concavity up and down, and others; we worked with a sample of 114 students, of them 73 units of analysis were control and 41 experimental; the data were collected with the written evaluative test, and they were processed obtaining descriptive statistics that allowed to say that the value Z = 7,09 is higher with respect to the critical z = 1,96 at 95% reliability, which allowed to reject the null hypothesis and accept the research hyp...
3
artículo
The purpose of the study was to test the effectiveness of the application of the first and second derivatives to analyze the mathematical functions in future teachers of Mathematics and Physics at UNHEVAL; for this, a cause-effect study and quasi-experimental design was carried out, hoping to optimize the learning of functions in a graphical and analytical way, by means of the exact location of the maximum and minimum points, inflection, determination of the concavity up and down, and others; we worked with a sample of 114 students, of them 73 units of analysis were control and 41 experimental; the data were collected with the written evaluative test, and they were processed obtaining descriptive statistics that allowed to say that the value Z = 7,09 is higher with respect to the critical z = 1,96 at 95% reliability, which allowed to reject the null hypothesis and accept the research hyp...
4
artículo
The relationship between executive functions (EF), creative personality, and academic performance in Argentine university students was examined. A total of 248 students (M = 22.97 years, SD = 4.43) from various Argentine provinces participated. The Adult Executive Functioning Inventory (ADEXI), the Cognitive Flexibility Scale, the Creative Behavior Scale (ECC), and the Creative Personality Scale (EPC) were used, along with academic performance data and sociodemographic information. Data were collected online through Google Forms and analyzed using Spearman correlations and mediation analysis with robust Maximum Likelihood estimator and Bootstrap. Cognitive flexibility exhibited the most robust correlation with grade point average (r = .281, p < .001), followed by working memory difficulties (r = -.234, p < .001). Creative personality correlated positively with grade point average (...
5
artículo
Objective: The objective was to determine the accuracy between functional swallowing (FS) and the Knebelman craniometric method (KCM) to measure occlusal vertical dimension (OVD) in total denture wearers. Materials and Methods: A quasi-experimental, prospective study was conducted considering the KCM diagnostic method as the gold standard compared to FS. All the totally edentulous patients attended at the School of Dentistry of the Universidad Nacional Mayor de San Marcos (n = 32) in 2018–2019 were evaluated. Previous informed consent was obtained from all patients. A Knebelman’s Craniometer was used to obtain longitudinal measurements measured in millimeters. The measurement was made with the Knebelman Craniometer by placing the tip into the external auditory canal inside the right meatus. On the other hand, for the FS method, the patients were seated comfortably with their back sup...
6
tesis doctoral
Esta investigación, realizada entre los estudiantes de la FCSEC-UNASAM, tuvo como objetivo general demostrar la eficacia de la aplicación del método del ‘Form-Function Analysis’ en el desarrollo de las habilidades lingüísticas en el aprendizaje de una segunda lengua: Reading-Writing y Listening-Speaking, agrupadas entre las habilidades receptivas y productivas, respectivamente, impactando sobremanera en el desarrollo del writing y del speaking y teniendo menor impacto, especialmente, en el listening. El tipo de estudio fue causal explicativa y el diseño, cuasi experimental. El tipo de muestra fue intencional, con una muestra no probabilística de 20 estudiantes. La medición de la variable dependiente se realizó con la aplicación del pre y postest, de 40 ítems cada uno, desagrupados a su vez en grupos de 10 ítems, representando a las 4 subdimensiones de las 2 dimensiones de...
7
artículo
The research objective was to establish the relationship that exists between family functioning and the levels of learning achievement of the students of the Alipio Ponce Vásquez Educational Institution in Puerto Maldonado. The research approach was quantitative, the design was non-experimental and the descriptive type was cross-sectional correlational. The population was made up of all the fifth and sixth grade students of the primary level of the Alipio Ponce Vásquez Educational Institution and a sample of 96 students was used, which was obtained by means of a probability sampling. The technique used for data collection was the survey, in the case of the variable family functioning and the documentary analysis in the case of the variable levels of learning achievement. On the other hand, the data collection instruments were the Family Cohesion and Adaptability Assessment Scale and th...
8
artículo
The research objective was to establish the relationship that exists between family functioning and the levels of learning achievement of the students of the Alipio Ponce Vásquez Educational Institution in Puerto Maldonado. The research approach was quantitative, the design was non-experimental and the descriptive type was cross-sectional correlational. The population was made up of all the fifth and sixth grade students of the primary level of the Alipio Ponce Vásquez Educational Institution and a sample of 96 students was used, which was obtained by means of a probability sampling. The technique used for data collection was the survey, in the case of the variable family functioning and the documentary analysis in the case of the variable levels of learning achievement. On the other hand, the data collection instruments were the Family Cohesion and Adaptability Assessment Scale and th...
9
artículo
Intelligence is a construct of notable impact in our sociocultural context, related to a wide range of conceptual and operational definitions which originate positions that highlights cognitive and abstract elements and emotional and social skills, as well was perspectives that are focused on processes underlying the intelligent performance, such as in the case of executive functions (EFs), which are configured as cognitive processes that make it possible the self-regulation (Miyake & Friedman, 2012). Similarly, there are approaches that give intelligence a relevant and predictive role of school performance, an aspect strengthened by the psychometric perspective, where the concept of intelligence has been closely linked to learning. In this line, we also find the classical perspective of crystallized Intelligence of Cattell (1943), which refers to the knowledge acquired through educa...
10
artículo
This investigation led proposes the articulation, in a conception as a whole, of a new theoretical model based on the stablishment of three functions of Public Relations that should be present in public and private organizations, that are, the relational function, the communicational function and the synergy function. This is an exploratory study, non-experimental, descriptive, comparative, and from an intracultural mode that took a sample of twenty executive officers of Public Relations and related, from public and private organizations in Peru. Among the main results it was found a high level of management in human relations in private organizations in Lima, but a low level in other cities of the country. These high and low levels were found in the management of the public controversy in organizations of Lima and provinces, respectively. Likewise, a high level of the subfunction unidir...
11
artículo
This investigation led proposes the articulation, in a conception as a whole, of a new theoretical model based on the stablishment of three functions of Public Relations that should be present in public and private organizations, that are, the relational function, the communicational function and the synergy function. This is an exploratory study, non-experimental, descriptive, comparative, and from an intracultural mode that took a sample of twenty executive officers of Public Relations and related, from public and private organizations in Peru. Among the main results it was found a high level of management in human relations in private organizations in Lima, but a low level in other cities of the country. These high and low levels were found in the management of the public controversy in organizations of Lima and provinces, respectively. Likewise, a high level of the subfunction unidir...
12
artículo
Introduction: The article examines the problem of psychomotor development of preschool children with intellectual disabilities. The researched problem affects learning, upbringing, and socialization of children of said category and its resolution requires implication of not only traditional but also non-traditional tools including correctional eurhythmics. The goal of the study is to develop the organizational and methodical basis for the development of psychomotor functions in preschool children with intellectual disabilities through the means of musical rhythmic exercises.Materials and methods: The basis of the research is formed by general scientific cognition methods: analysis, synthesis, comparison, generalization; pedagogical experiment (ascertaining, forming, control), and empirical data analysis. The data acquired in the course of the study were processed in Excel via the methods...
13
artículo
Introduction: The article examines the problem of psychomotor development of preschool children with intellectual disabilities. The researched problem affects learning, upbringing, and socialization of children of said category and its resolution requires implication of not only traditional but also non-traditional tools including correctional eurhythmics. The goal of the study is to develop the organizational and methodical basis for the development of psychomotor functions in preschool children with intellectual disabilities through the means of musical rhythmic exercises.Materials and methods: The basis of the research is formed by general scientific cognition methods: analysis, synthesis, comparison, generalization; pedagogical experiment (ascertaining, forming, control), and empirical data analysis. The data acquired in the course of the study were processed in Excel via the methods...
14
artículo
Introduction and objectives: The objective of this study is to determine if the type of cleft lip and palate is associated with a higher risk of alteration of the Eustachian tube. Materials and methods: A descriptive case series study was carried out with an inferential analysis of children operated on for cleft lip and palate at the San Bartolomé hospital during the years 2018 and 2019. Results: 48 patients with tympanometry were evaluated, 62.5% male (n = 30) and 37.5% female (n = 18), the mean age was 1.3 years. The type of cleft lip and palate was determined using the Veau classification, the most frequent type found was Veau type III: 62.5% (n = 30), the least frequent type was Veau I with 4.2% (n = 2). The evaluation of the function of the Eustachian tube was performed with tympanometry, defining the type B curve as pathological. In the studygroup, there was an overall prevalence ...
15
artículo
Introduction and objectives: The objective of this study is to determine if the type of cleft lip and palate is associated with a higher risk of alteration of the Eustachian tube. Materials and methods: A descriptive case series study was carried out with an inferential analysis of children operated on for cleft lip and palate at the San Bartolomé hospital during the years 2018 and 2019. Results: 48 patients with tympanometry were evaluated, 62.5% male (n = 30) and 37.5% female (n = 18), the mean age was 1.3 years. The type of cleft lip and palate was determined using the Veau classification, the most frequent type found was Veau type III: 62.5% (n = 30), the least frequent type was Veau I with 4.2% (n = 2). The evaluation of the function of the Eustachian tube was performed with tympanometry, defining the type B curve as pathological. In the studygroup, there was an overall prevalence ...
16
tesis doctoral
Descargue el texto completo en el repositorio institucional de la Universidade Estadual de Campinas: https://hdl.handle.net/20.500.12733/1641647
17
artículo
This study describes the axiological model of the technological package as a pre-patentable foundation of innovation, designed to articulate the value dimensions underpinning validation, transfer, and potential impact on preventive health. A descriptive, non-experimental study with a qualitative–analytical approach was conducted through structured documentary review and hermeneutic content analysis. The results present a systemic model that integrates ethical, technical, and social principles, structuring the innovation process from need identification to product commercialization and maintenance. This framework demonstrates that axiological coherence provides the technical robustness, sustainability, and social relevance required for responsible biotechnological innovation. The study concludes that the axiological foundation enables the transformation of scientific knowledge into pre-...
18
artículo
In Mexico, a high percentage of young people experience symptoms of generalized anxiety, which are associated with difficulties in executive functions (EF). However, previous studies have shown inconsistent results, as they often rely solely on either objective or subjective measures. Therefore, this study focused on analyzing the relationship between generalized anxiety and EF using both a neuropsychological battery and a self-report questionnaire, in order to provide a more comprehensive understanding of cognitive functioning in adolescents. A quantitative, non-experimental, cross-sectional, correlational, and explanatory design was employed. The sample consisted of 96 adolescents between 12 and 15 years old from the state of Puebla, Mexico. A total of 10.41% of participants presented severe symptoms of generalized anxiety. A significant relationship was found between anxiety and one o...
19
artículo
Objective: Determine the influence of family functionality on adolescent depression at the private educational institution "Gran Amauta de Motupe" Lima, 2018. Material and method: The design used was non-experimental, cross-sectional, causal correlational, the instruments used were : the Family Cohesion and Adaptability Assessment Scale, FACES IV, by Olson and the Beck Depression Inventory (IDB-II). Results: The sample consisted of 91 adolescents from fi rst to fifth grade of secondary school between 12 and 17 years of age of secondary level. The general analysis showed a 51.6% minimum depression, 28.5% mild, 10.9% moderate and 8.7% severe. While the family functionality showed 65.9% intermediate functionality and 34% low. Conclusion: Adolescents with lower family functionality tend to have greater depressive symptomatology.
20
artículo
In order to determine whether family functioning predicts the level of resilience in parents facing the impact of the COVID-19 pandemic, a predictive and cross-sectional study was conducted on a sample of 183 parents from the department of La Libertad, who were selected under a non-probabilistic purposive sampling. Two instruments were used to collect data: Cohesion and Family Adaptability Evaluation Scale (CESF) and the Brief Resilient Coping Scale (BRC). Based on a linear regression analysis, an adequate model fit is observed (F-test = 35.924, p < .001), where, family functioning (β = .407, p < .05) is a variable that significantly predicts resilience (adjusted R2 = .161). Also, the t-values of the beta regression coefficients of the predictor variable are highly significant (p < .01). In conclusion, the level of family functioning predicts the degree of resilient coping in p...