Objective: The objective was to determine the accuracy between functional swallowing (FS) and the Knebelman craniometric method (KCM) to measure occlusal vertical dimension (OVD) in total denture wearers. Materials and Methods: A quasi-experimental, prospective study was conducted considering the KCM diagnostic method as the gold standard compared to FS. All the totally edentulous patients attended at the School of Dentistry of the Universidad Nacional Mayor de San Marcos (n = 32) in 2018–2019 were evaluated. Previous informed consent was obtained from all patients. A Knebelman’s Craniometer was used to obtain longitudinal measurements measured in millimeters. The measurement was made with the Knebelman Craniometer by placing the tip into the external auditory canal inside the right meatus. On the other hand, for the FS method, the patients were seated comfortably with their back sup...