Introduction: The present study arises in response to the sustained increase in dengue outbreaks in Latin America, with special emphasis on the state of Zulia, Venezuela. This region, composed of 21 municipalities, is highly vulnerable to dengue transmission. Given this scenario, it is essential to have tools that allow early detection of outbreaks and, thus, optimize prevention and public health intervention strategies. The main objective is to develop an early warning system for dengue outbreaks using machine learning (ML) techniques. Materials and methods: Several data sources are integrated: epidemiological information, meteorological parameters, El Niño and La Niña (Niño 3.4 Index), socioeconomic and demographic variables. Two ML models were used: Support Vector Machine for regression (SVM-R) and Gaussian Process Regression (GPR). Results: The predictions obtained showed remarkab...

El preocupante aumento de casos de dengue en Perú, especialmente en Lima, ha generado alarma, con un asombroso incremento del 323.5 % de 63,168 casos en 2022 a 268,660 casos hasta la semana 43 de 2023. Lima experimento un drástico aumento del 3,190.6 %, pasando de 938 casos en 2022 a 30,946 hasta la semana 43 de 2023. Esta situación plantea riesgos significativos para la salud en Lima, con una población densamente poblada de aproximadamente 9,674,755 habitantes, y la posibilidad de tensionar su sistema de salud debido a la falta de experiencia con el dengue, cuyos primeros casos autóctonos se reportaron en febrero de 2022. Para abordar este desafío, se propone un proyecto que visualiza informes de casos de dengue en tiempo real, permitiendo intervenciones inmediatas. La falta de control en áreas infectadas podría llevar a la saturación del sistema de salud, especialmente con el ...

About IMMUNOPERU 2025: This IUIS-ALACI-PSI course has brought together a diverse group of students, immunologists and experts to share their distinct perspectives, skills and expertise. The focus was on a variety of endemic and emerging diseases related to environmental and climate change. The goal was to catalyze the development of novel concepts, methods and approaches in addressing these emerging challenges. MAIN TOPICS: The course has addressed the Impact of environmental exposures on immunity in infectious disease, chronic inflammation and cancer with particular attention to: Changes in microbial communities and their metabolites that drive inflammatory disease (eg. effects of antibiotics, dietary and other factors) Environmental cues and pollutants linked to the development of hematologic malignancies. The impact of climate change on endemic infectious diseases (eg. Tuberculosis, D...

In Latin America, the first months of 2016 were marked by the increasing reports of microcephaly, which was shortly afterwards shown to have been caused by the Zika virus. Initially, its transmission was typified as metaxenic (caused by the Dengue mosquito Aedes aegypti); later, evidences of sexual transmission were detected. Thus, the Ministry of Health of Peru required to evaluate the response capacity of the reproductive health services to needs and critical knots and to draft a plan to improve the offer. In the case of Lima, EsSalud facilities were also included. Through individual and group interviews, and check lists and observation lists, key variables of the health system were analyzed. The budget of the regions was always lower than that requested; the family planning budget was expended in other uses. Office hours were limited. The staff skills on both intrauterine device (IUD)...