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1
artículo
Publicado 2000
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This study deals with the fuel emissions and their impact on the environment. It aims to identify and assess air pollutants at various points in the city of Lima, to establish preventive measures to reduce pollutants. This study finds an increase of 50% specifically in phase sampling and measurement.
2
artículo
Publicado 2000
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This study deals with the fuel emissions and their impact on the environment. It aims to identify and assess air pollutants at various points in the city of Lima, to establish preventive measures to reduce pollutants. This study finds an increase of 50% specifically in phase sampling and measurement.
3
artículo
Publicado 2020
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Benthic organisms have been proposed as good indicators of disturbance in marine environments, particularly because most toxins fall to the bottom of the sea affecting benthic communities. A non-invasive method for collecting coelomocytes was developed using the marine polychaete Eurythoe complanata with potential applications in xenobiotic toxicology. The extrusion method used produced the expulsion of 95% of the coelomic fluid, showing a greater efficiency than the puncture method in Lumbricus terrestris with regard to the total number of coelomocytes and cellular viability. The total coelomocyte count by this method was 6 -1 6 -12.6 x 10 cells·mL vs 1.4 x 10 cells·mL for the puncture method. The results indicate that coelomocyte numbers completely recover at 20 days after extrusion, using the total cell count, cell viability and differential count. This method was developed to study...
4
artículo
Publicado 2015
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The objective of this study was to evaluate the quality of raw milk in seven representative basins of the region Puno. The results were compared with the standards established by the International Standard for milk and milk products NTP 200.001-2003 and the Official Mexican Standard NOM-155-SCFI-2012 for the parameters of protein and lactose in the absence of Peruvian parameters. For physicochemical characterization pH, acidity, density, fat, protein, lactose, total solids, fat solids was determined microbiological analysis of E. coli and mesophilic, just as we also performed the study spanned pesticide residue analysis such as organochlorines, organophosphates, carbamates and pyrethroids with sensitivity 1.0ug/g sample which gave negative results for the four groups of pesticides, the physicochemical determinations over 50% of the basins (except for pH and acidity) is found within the s...
5
artículo
Publicado 2002
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With the beginning of the Industrial Era, specially after the II World War, man lives exposed progressively to more pollutants and has confronted huge environmental disasters like Minamata, Bophal, and Chernovyl. Cadmium is an environmental and industrial toxic pollutant that produces in man effects at the enzymatic, renal, respiratory and digestive levels, aggravated by its very extended mean life. To face this problem, we would have to make a survey of the principal sources of industrial pollution, mainly metallurgic, in order to protect the worker, applying TLVs and BEIs criteria concurrent with the state of the art.
6
artículo
Publicado 2011
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In occupational health to control risk magnitude we apply threshold limit values. Man at high altitude has anatomical-physiological variants in his respiratory system; most important are increases in thoracic capacity, pulmonary ventilation, alveolar/capillary diffusion, and arterial oxygen content. Physiological safe work at high altitude consists in the organism not using extra energy to compensate barometric pressure fall. In respiratory occupational toxicology we must initiate correction when ventilatory response to hypobaric hypoxia becomes unsafe and this occurs at 8 000 feet above sea level. Accordingly we should correct exposure limits value applying to work at high altitude. In order to establish safe parameters of toxicological exposition at high altitude it is necessary to investigate these aspects in high altitude workers.
7
artículo
Publicado 2015
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The objective of this study was to evaluate the quality of raw milk in seven representative basins of the region Puno. The results were compared with the standards established by the International Standard for milk and milk products NTP 200.001-2003 and the Official Mexican Standard NOM-155-SCFI-2012 for the parameters of protein and lactose in the absence of Peruvian parameters. For physicochemical characterization pH, acidity, density, fat, protein, lactose, total solids, fat solids was determined microbiological analysis of E. coli and mesophilic, just as we also performed the study spanned pesticide residue analysis such as organochlorines, organophosphates, carbamates and pyrethroids with sensitivity 1.0ug/g sample which gave negative results for the four groups of pesticides, the physicochemical determinations over 50% of the basins (except for pH and acidity) is found within the s...
8
artículo
Publicado 2020
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The aim of this research was to use the benthic macroinvertebrates (MIB) and toxicological assessment tests to evaluate the water and sediment quality of the Rimac river (Lima-Peru) in wet and dry seasons in 2009. Twelve sampling stations (E1 to E12) were established, considering the sources of contamination. At each station, physical and chemical data, MIB, and water and sediment toxicity with Daphnia magna and Chironomus calligraphus were measured. The wet season had higher pH; however, higher values of specific conductivity, total solids, dissolved oxygen and transparency were observed in the dry season. Differences in the abundance of Planorbidae, Baetidae, Chironomidae, Tipulidae and Empididae were observed between wet and dry seasons. The diversity and evenness index were higher in wet season, but the dominance and abundance index were higher in the dry season. The dendrogram...
9
artículo
Publicado 2000
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The growing interest in natural medicine makes it necessary to study plant properties as well as their possible secondary effects. In recent years the toxic effects of many medicinal plants on the preimplantational mouse embryo development have been studied. Many of them produce malformations and alterations in the embryonic development. Ruta graveolens "ruda", Origanum vulgare "oregano" and Persea americana "palta" are used in rural areas to menstrual colic and to provoke abortion (estrella, 1995). This study is aimed at assessing "in vivd'the effect of extracts of "oregano", "ruda" and "palta" to 20% on the morphology and growth of preimplantational mouse embryos.
10
artículo
Publicado 2020
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Potato tocosh is a naturally processed potato for nutritional and curative purposes from traditional Peruvian medicine. The aim of this study was to investigate the acute and sub-acute toxicity of tocosh flour (TF). For sub-acute toxicity, TF was administered orally to rats daily once a day for 28 days at doses of 1000 mg/kg body weight (BW). Animals were observed for general behaviors, mortality, body weight variations, and histological analysis. At the end of treatment, relative organ weights, histopathology, hematological and biochemical parameters were analyzed. For acute toxicity, TF was administered orally to mice at doses of 2000 and 5000 mg/kg BW at a single dose in both sexes. Body weight, mortality, and clinical signs were observed for 14 days after treatment. The results of acute toxicity showed that the median lethal dose (LD50) value of TF is higher than 2000 g/kg BW but les...
11
artículo
Publicado 2020
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The objective of this study was to evaluate the toxicological risk due to exposure to soils with the presence of lead and cadmium in areas surrounding the Infantas Industrial Park in Los Olivos - Lima (2018). 40 soil samples were taken, 20 samples in the Carabayllo urbanization and 20 samples in the Villa del Norte urbanization. It was obtained that the concentration of Pb and Cd in Urb. Carabayllo had a mean of 66.97 mg / kg and 0.86 mg / kg; for Urb. Villa del Norte it is 51.43 mg / kg and 0.73 mg / kg respectively. The concentrations obtained comply with the Environmental Quality Standard (ECA) of the Ministry of the Environment of Peru. The Exposure Dose (DE) was estimated in the Carabayllo urbanization, for adults, a DEPb = 0.000143 mg / kg / day and DECd = 0.000002 mg / kg / day were obtained; and for children, a DEPb = 0.002494 mg / kg / day and DECd = 0.000032 mg / kg / day. In t...
12
artículo
Publicado 2020
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The objective of this study was to evaluate the toxicological risk due to exposure to soils with the presence of lead and cadmium in areas surrounding the Infantas Industrial Park in Los Olivos - Lima (2018). 40 soil samples were taken, 20 samples in the Carabayllo urbanization and 20 samples in the Villa del Norte urbanization. It was obtained that the concentration of Pb and Cd in Urb. Carabayllo had a mean of 66.97 mg / kg and 0.86 mg / kg; for Urb. Villa del Norte it is 51.43 mg / kg and 0.73 mg / kg respectively. The concentrations obtained comply with the Environmental Quality Standard (ECA) of the Ministry of the Environment of Peru. The Exposure Dose (DE) was estimated in the Carabayllo urbanization, for adults, a DEPb = 0.000143 mg / kg / day and DECd = 0.000002 mg / kg / day were obtained; and for children, a DEPb = 0.002494 mg / kg / day and DECd = 0.000032 mg / kg / day. In t...
13
artículo
Publicado 2016
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Snakebite envenoming is a neglected public pathology, affecting especially rural communities or isolated areas of tropical and subtropical Latin American countries. The parenteral administration of antivenom is the mainstay and the only validated treatment of snake bite envenoming. Here, we assess the efficacy of polyspecific anti-Bothrops serum (α-BS) produced in the Instituto Nacional de Salud (INS, Peru) and at the Fundação Ezequiel Dias (FUNED, Brazil), to neutralize the main toxic activities induced by five medically-relevant venoms of: Bothrops atrox, B. barnetti, and B. pictus from Peru, and the Brazilian B. jararaca and B. leucurus, all of them inhabiting different geographical locations.
14
artículo
Publicado 2016
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El texto completo de este trabajo no está disponible en el Repositorio Académico UPC por restricciones de la casa editorial donde ha sido publicado.
15
artículo
Publicado 2018
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Due to its extensive use in various livestock production activities and its use in human health care, antibiotics have become an environmental problem that draws the attention of the scientific community. Several research works report their presence in different ecosystems compartments, as well as their impact in organisms that inhabit these ecosystems which are being investigated by this community; until now, it has been reported problems of bacterial resistance and damages at DNA level in living beings, among others; in this perspective it is necessary to perform monitoring in various environmental matrixes, in order to detect and quantify their presence, to have a better understanding of their long-term effects on living beings. In this sense, it addresses aspects that determine their presence in the ecosystem, as well as shows results of works evaluating their removal of contaminated...
16
artículo
Publicado 2018
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Due to its extensive use in various livestock production activities and its use in human health care, antibiotics have become an environmental problem that draws the attention of the scientific community. Several research works report their presence in different ecosystems compartments, as well as their impact in organisms that inhabit these ecosystems which are being investigated by this community; until now, it has been reported problems of bacterial resistance and damages at DNA level in living beings, among others; in this perspective it is necessary to perform monitoring in various environmental matrixes, in order to detect and quantify their presence, to have a better understanding of their long-term effects on living beings. In this sense, it addresses aspects that determine their presence in the ecosystem, as well as shows results of works evaluating their removal of contaminated...
17
artículo
Publicado 2018
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Due to its extensive use in various livestock production activities and its use in human health care, antibiotics have become an environmental problem that draws the attention of the scientific community. Several research works report their presence in different ecosystems compartments, as well as their impact in organisms that inhabit these ecosystems which are being investigated by this community; until now, it has been reported problems of bacterial resistance and damages at DNA level in living beings, among others; in this perspective it is necessary to perform monitoring in various environmental matrixes, in order to detect and quantify their presence, to have a better understanding of their long-term effects on living beings. In this sense, it addresses aspects that determine their presence in the ecosystem, as well as shows results of works evaluating their removal of contaminated...
18
artículo
Publicado 2018
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Due to its extensive use in various livestock production activities and its use in human health care, antibiotics have become an environmental problem that draws the attention of the scientific community. Several research works report their presence in different ecosystems compartments, as well as their impact in organisms that inhabit these ecosystems which are being investigated by this community; until now, it has been reported problems of bacterial resistance and damages at DNA level in living beings, among others; in this perspective it is necessary to perform monitoring in various environmental matrixes, in order to detect and quantify their presence, to have a better understanding of their long-term effects on living beings. In this sense, it addresses aspects that determine their presence in the ecosystem, as well as shows results of works evaluating their removal of contaminated...
19
tesis de grado
Publicado 2024
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En el presente estudio se investigaron las propiedades fitoquímicas farmacológicas y toxicológicas de la Mentha spicata para determinar diferentes beneficios para la salud. Se realizó una revisión sistemática utilizando el método PICO en los buscadores PUBMED, SCIELO y GOOGLE ACADÉMICO, encontrando 23,786 artículos, de los cuales se seleccionaron 60 artículos Se seleccionaron y revisaron críticamente 20 artículos en su aspecto fitoquímico, 20 artículos en su aspecto farmacológico y 20 artículos en su aspecto toxicológico. A nivel fitoquímico se determinó que el aceite esencial de Mentha spicata tiene como componentes principales y mayoritario a la carvona y limoneno estos serían los responsables de los efectos farmacológicos como son los efectos antioxidantes, anticancerígenos, antimicrobianos y antinflamatorios. Es importante destacar que las investigaciones toxico...
20
artículo
Publicado 2008
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El mercurio, metal pesado ampliamente utilizado por el hombre, es muy tóxico; produce daño al sistema nervioso central, perturbaciones del comportamiento y lesiones renales. Se acumula en todos los seres vivos y no es esencial para ningún proceso biológico. La toxicidad del mercurio está directamente relacionada con su estado químico. El metilmercurio es la forma más dañina, con efectos neurotóxicos en adultos y en fetos de madres expuestas. El mercurio metálico no es menos tóxico. Las sales de mercurio inorgánico afectan directamente al riñón. Clínicamente, en la exposición ocupacional a mercurio se encuentra la triada clásica: temblor, alteración de la personalidad y estomatitis. En los últimos años se ha demostrado también alteración en la visión cromática. La exposición aguda se evalúa midiendo el mercurio en la sangre, mientras que la exposición crónica y...
