The growing interest in natural medicine makes it necessary to study plant properties as well as their possible secondary effects. In recent years the toxic effects of many medicinal plants on the preimplantational mouse embryo development have been studied. Many of them produce malformations and alterations in the embryonic development. Ruta graveolens "ruda", Origanum vulgare "oregano" and Persea americana "palta" are used in rural areas to menstrual colic and to provoke abortion (estrella, 1995). This study is aimed at assessing "in vivd'the effect of extracts of "oregano", "ruda" and "palta" to 20% on the morphology and growth of preimplantational mouse embryos.

El creciente interés por la medicina natural hace necesaria la evaluación de las propiedades de las plantas, así como de sus posibles efectos secundarios. En años recientes se han reportado los efectos tóxicos de varias plantas medicinales sobre el desarrollo preimplantacional de ratón (Benavides et al, 1998; Benavides et al., 1999), muchas de las cuales producen malformaciones y alteraciones en el desarrollo embrionario. Ruta graveolens "ruda", Origanum vulgare "orégano" y Persea americana "palta" son usadas folklóricamente para aliviar cólicos menstruales y como abortivos (Estrella, 1995). El objetivo del presente trabajo es evaluar in vivo el efecto del extracto acuoso de orégano, ruda y palta al 20% sobre la morfología y el desarrollo de embriones preimplantacionales de ratón.

The sample that is the object of this research work is a kind of bituminous coal, from the Mount Huáscar, province of Oyón, department of Lima. Provided by the Coal Mine Company. The mineralogical characterization of the sample coal, to show the presence of the following minerals: Graphite (grf) and Pyrite (py). The percentage distribution indicates graphite and 96,91% 3,09% pyrite, the particles are mostly free, accordingly modal analysis indicates that the degree of liberation of graphite and pyrite is 100%, that is counted all particles are free, as can be seen in the photos N.º 1, 2 ,3 and 4. Based on the characterization done it can be concluded that sulfur is in the pyrite, which is the polluter coal. Metallurgical tests were conducted preliminary gravity and flotation; being the outcome of the gravity is not satisfactory. The three tests metallurgical more representative of flo...