Multidisciplinary Management of Pancreatic Adenocarcinoma: Clinical Practice Guideline AUNA

• Autores: Montenegro Beltrán, Paola, Hurtado de Mendoza, Fernando, Suazo Casanova, Fernando, Castro Oliden, Víctor, Pacheco Román, Cristian, Rabanal Carretero, Connie, Young Tabusso, Frank, Luque Vásquez, Carlos, Targarona Módena, Javier, Sarria Bardales, Gustavo, Vizcarra Ladrón de Guevara, Bernardo Jesús, Lachos Dávila, Alberto, Martínez Pérez, David, Rau Vargas, Christian, Dyer Velarde-Alvarez, Richard, Mora Alferez, Pamela, Lau Manrique, Diana, Ramos Morante, Carlos, Palacios Salas, Fernando, Li Salvatierra, Bruno, Guerrero Gil, Jorge, Yana Pari, Edgar, Arapa García, Juan Carlos, Carrillo Díaz, Álvaro, Posada Arango, Ana María, Tarazona López, Deysi, Serrano Cardoso, Mariana, Failoc Rojas, Virgilio Efraín, Aliaga Llerena, Karina, Pérez Tazzo, Leydi Laura, Gil-Olivares, Fradis, Muro Cieza, Johanny Fidela de Fátima, Calderillo Ruiz, Germán, León Chong, Jorge
• Formato: artículo
• Fecha de Publicación: 2022
• Institución: Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo
• Repositorio: Revista del Cuerpo Médico Hospital Nacional Almanzor Aguinaga Asenjo
• Lenguaje: español
• OAI Identifier: oai:cmhnaaa.org.pe:article/1518
• Enlace del recurso: https://cmhnaaa.org.pe/index.php/rcmhnaaa/article/view/1518
• Nivel de acceso: acceso abierto
• Materia: Cáncer de páncreas; Guía de práctica clínica; Diagnóstico; Obstrucción del conducto biliar; Quimioterapia; Pancreatic cancer; Clinical practice guideline; Diagnosis; Bile duct obstruction; Chemotherapy

Introduction: This article provides recommendations for the Multidisciplinary Management of Pancreatic Adenocarcinoma in the RED AUNA. Methods: A systematic search of clinical practice guidelines (CPG) similar to topics of interest was developed, it was assessed with the AGREE II instrument, a list of questions was elaborated under the PICO structure, a de novo search was carried out prioritizing reviews systematic with or without meta-analysis, followed by primary studies, the elaboration of the evidence tables and the evaluation of the global quality for the outcomes of the clinical questions was carried out following the GRADE methodology. Results: 5 PICO questions corresponding to initial management and systemic management were formulated with 18 recommendations regarding the most effective method for pathological diagnosis, biliary drainage and the most effective and safe systemic treatment in the neoadjuvant, adjuvant and metastatic setting. Conclusions: This article summarizes the methodology and evidence-based recommendations of the CPG for the multidisciplinary management of pancreatic adenocarcinoma of the AUNA Clinic Network.