Objetivo: Determinar la utilidad de los marcadores ultrasonográficos entre las semanas 11+0 – 13+6 de embarazo para predecir cromosomopatías en gestaciones únicas en el Instituto Nacional Materno Perinatal de Lima – Perú entre el 01 de enero de 2014 y el 31 de diciembre de 2015. Material y métodos: Se realizó un estudio observacional, retrospectivo, transversal y analítico de tipo validez de prueba diagnóstica. Resultados: Se estudió 413 pacientes a quienes se les realizó evaluación ultrasonográfica entre las 11+0 – 13+6 semanas de gestación. El 6,3% (n = 26) de gestantes tuvo translucencia nucal aumentada (> 2.5mm) y esto aumentó en 3,24 (IC al 95%: 1,82 – 5,77; p < 0,001) veces el riesgo de Síndrome de Down, mientras el 3,6% (n = 15) de gestantes tuvo hipoplasia/ausencia del hueso nasal lo que aumentó en 4,91 (IC al 95%: 1,79 – 13,51; p < 0,001) veces el riesg...

Twin-to-twin transfusion syndrome is a severe complication of twin monochorial pregnancies manifested with one hypovolemic fetus (donor) and another hypervolemic fetus (receiver). Perinatal mortality is about 90 to 100% if untreated. The accepted treatment is fetoscopy and selective laser photocoagulation of the placental shunts that connect both twins. Currently, this specialized procedure is only performed in our institution. We present the first cases of monochorionic twin pregnancy complicated with twin-to-twin transfusion syndrome that underwent laser photocoagulation and fetoscopy.

Objective. To determine the usefulness of the mean pulsatility index (PI) of uterine artery doppler before 30 gestation weeks’ as a predictor of macrosomia in newborns treated at the National Perinatal Maternal Institute during the period 2011- 2012. Material and methods. A retrospective, cross-sectional and analytical study. It was determined the mean pulsatility index of the uterine arteries to 232 pregnant women under 30 gestation weeks’ and birth weight was calculated according to birth gestational age for two groups, the first with infants with appropriate birth weight and the second with macrosomic neonates (n = 18/ 7,8%), which were compared using standard deviations, Pearson correlation, Student t test and receiver-operator curve (ROC). Results. Variation was found between the two groups in the four mean indices (peak systolic, peak diastolic, pulsatility index and resistance...

Objective. To determine the usefulness of the mean pulsatility index (PI) of uterine artery doppler before 30 gestation weeks’ as a predictor of macrosomia in newborns treated at the National Perinatal Maternal Institute during the period 2011- 2012. Material and methods. A retrospective, cross-sectional and analytical study. It was determined the mean pulsatility index of the uterine arteries to 232 pregnant women under 30 gestation weeks’ and birth weight was calculated according to birth gestational age for two groups, the first with infants with appropriate birth weight and the second with macrosomic neonates (n = 18/ 7,8%), which were compared using standard deviations, Pearson correlation, Student t test and receiver-operator curve (ROC). Results. Variation was found between the two groups in the four mean indices (peak systolic, peak diastolic, pulsatility index and resistance...

Fetal growth restriction (RCF) is a clinical circumstance in which the fetus does not express its genetic potential for growth and as a final result a decrease in body weight occurs, which is below the 10th percentile for gestational age, in a selected growth curve. Among the etiological factors include: maternal, fetal and placental causes. It is classified as Precocious and late. The appropriate time for delivery is determined by gestational age and fetal condition.

Fetal growth restriction (RCF) is a clinical circumstance in which the fetus does not express its genetic potential for growth and as a final result a decrease in body weight occurs, which is below the 10th percentile for gestational age, in a selected growth curve. Among the etiological factors include: maternal, fetal and placental causes. It is classified as Precocious and late. The appropriate time for delivery is determined by gestational age and fetal condition.