We review the  latest insigths on the understanding of immununosenenscense, or aging of the inmune systeni. This process results from  the interaction between bothl inborn (genetic) and acquired (nutritional status, lifestyle,  and host-parasitic interaction) features. Among genetic features, genetically controled expression of HLA system molecules on inmune cells and possible linkage of some allelies expression to  longer longevity stand out. Other main features are changes of the aged patient inmune system and understand of  of thymus involution as well as changes in the distribution, quality, and quantilty of lympliocyte sub-populations. Another ¡nmunosenescence factor is the niodification ¡n the production of cytokines, regulatory liorniones of the inmune system.  Adequate understanding of above factors will lead to prevention follow-up, and inmune intervention of aged   pat...

This study analizes Daniel Alcides Carrion role as a cultural hero and central element of Peruvian medical tradition. We verify the meaning of the elaboration process of Carrion’s experiment in a political struggle and national reconstruction scenery that converges with the beginning of the century aristocratic elite positivism. Social recomposition of medical institutions and the emergent fraction entrance to the Faculty of Medicine makes end of the XIX century-Carrion’s created image to become a neutral icon at the present time, amenable to absolute reivindication by all sectors as it is deeply rooted in the past with no current presence. A cultural imaginary analysis of Peruvian Medical School development (1886-1956) is done, as during this period San Fernando produced the country’s largest and best quality medical knowledge. We conclude that confluence of local medical imaginary e...

Objective: To evaluate the effect of Ibuprofen and Celecoxib on fertility in female rats. Material and methods: 22 14-week-old Holtzman female rats were selected, which were in the diestrus stage, determined by vaginal cytology evaluation, who were distributed into three groups, and treated orally for two days, as follows: Group control: physiological saline 1 ml/100g, experimental group 1: Ibuprofen 120 mg/kg/day and experimental group 2: Celecoxib 20 mg/kg/day. After two days they were mated with the males, until the end of the next estrous cycle. The rats were euthanized 10 days after separation from the male and the presence and number of implanted embryos were evaluated. Results: The percentage of rats that did not present pregnancy was 14.3, 71.4 and 37.5% in the control, Ibuprofen and Celecoxib groups respectively; while the average number of embryos implanted were: control group ...