1
artículo
Publicado 2024
Enlace
Enlace
Crohn’s disease (CD) is a chronic, progressive inflammatory disease with complications that impact the well-being of patients. The therapeutic advances achieved in recent decades, especially through the advent of biological therapy, have allowed for a transformation in the approach and management of CD, thereby modifying the course of this disease. However, a significant number of patients do not experience a satisfactory response to these drugs or lose it during the course of the disease. In this scenario, a viable alternative is to switch medications. Upadacitinib, a novel Janus kinase inhibitor, has emerged as a promising strategy for the management of CD. We presented two cases of patients with CD refractory to conventional therapy and biological therapy, who responded successfully to treatment with upadacitinib.
2
artículo
Publicado 2024
Enlace
Enlace
Introduction: Despite advancements in therapeutic strategies, corticosteroids continue to play a role in inducing remission in Inflammatory Bowel Disease (IBD). Unfortunately, these drugs are often misused. Objectives: To assess the dose and duration of corticosteroid therapy, and the subsequent change in treatment among patients with IBD. Materials and methods: We conducted a descriptive, retrospective observational study on patients with IBD under follow-up at the IBD Program of Clínica Universidad de los Andes from January 2021 to August 2022. Results: Four hundred and thirty-two IBD were included, with 63% being women, with a median age of 42 years (14-94), 66% had ulcerative colitis (UC). Sixty-six percentage of patients had received corticosteroids during the course of their disease (range 1-9 times) for a median duration of 12 weeks (2-48 weeks), with prednisone being th...
3
artículo
Publicado 2024
Enlace
Enlace
Telemedicine has grown during the COVID-19 pandemic. Gastroenterology at Clínica Universidad de los Andes has continued it post-pandemic. Usability is the measure by which users evaluate the effectiveness, efficiency, and satisfaction in telemedicine. The usability of this type of consultation in Chile is unknown. Objective: To evaluate the level of usability among patients attended through teleconsultations in Gastroenterology at Clínica Universidad de los Andes (March-August 2023). Materials and methods: A cross-sectional descriptive study on the level of usability using the adapted and modified Telehealth Usability Questionnaire. It consists of 12 items (score range 12-84) and comprises 2 factors: effectiveness and ease of use. Sociodemographic characteristics were also evaluated. Results: A total of 150 questionnaires were analyzed. A high level of usability was observed (median: 8...
4
artículo
Publicado 2024
Enlace
Enlace
Introducción: La endoscopia juega un papel fundamental en la enfermedad inflamatoria intestinal (EII), y se hace esencial en el diagnóstico, monitoreo del tratamiento, y detección y manejo de complicaciones. Materiales y métodos: la Organización Panamericana de Crohn y Colitis (PANCCO) la Sociedad Interamericana de endoscopia (SIED) designó 22 expertos latinoamericanos en EII para desarrollar un estudio de consenso utilizando el método Delphi modificado, basado utilizando la mejor evidencia disponible. Un grupo de trabajo de 22 miembros de 9 países, se identificaron 15 temas y formularon 98 declaraciones, quienes participaron en 2 rondas de votación. Se definió como el acuerdo de ≥80% de los expertos para cada declaración. Resultados: Posterior a la votación de todas las afirmaciones, se obtuvieron 8 afirmaciones que no alcanzaron el 80% de consenso entre los participantes,...
5
artículo
Publicado 2024
Enlace
Enlace
Introduction: Endoscopy plays a fundamental role in inflammatory bowel disease (IBD), and becomes essential in diagnosis, treatment monitoring, and detection and management of complications. Materials and methods: The Pan American Crohn's and Colitis Organization (PANCCO) and the Inter-American Society of Endoscopy (SIED) appointed 22 Latin American experts in IBD to develop a consensus study using the modified Delphi method, based on the best available evidence. A working group of 22 members from 9 countries identified 15 topics and formulated 98 statements, who participated in 2 rounds of voting. It was defined as agreement of ≥80% of experts for each statement. Results: After the voting of all the statements, 8 statements were obtained that did not reach 80% consensus among the participants, so the questions were reconsidered in the Coordinating Committee of the consensus with the p...
