El objetivo de la investigación fue determinar el rendimiento de extractos: etanólico y acuoso obtenidos por infusión de hojas postcosecha de Vaccinium corymbosum (arándano azul); con contenido de fenoles y actividad antioxidante, metedología utilizada: estudio básico, descriptivo, transversal y experimental. Resultados de 100g hojas post cosecha seleccionadas se obtiene 28.44 g de material seco que sometido a molienda con molino manual obteniendo 73.65 % de materia conformado por partículas menores a 1.0 mm. Con estas partículas se obtienen extracto acuoso y etanólico al 1.0 % y evaporados sus solventes los rendimientos de extracto libre de solvente son 0.682 % y 0.511 %, respectivamente. Las infusiones acuosas 1.0 % y etanólicas 1.0 % tienen un contenido de fenoles totales que son equivalentes a soluciones de ácido gálico de 73.116 y 30.419mg/100 mL, respectivamente. Y tien...

Introduction: Non-responsible self-medication leads to low effectiveness and insecurity in treatments, damage of health and patient dissatisfaction. Objective: To identify factors associated with non-responsible self-medication in the Peruvian population. Material and Methods: An analytical cross-sectional study was conducted based on the secondary analysis of the National Survey of Users Satisfaction in Health performed in Peru in 2016. It included 3849 users of pharmaceutical establishments. Chi-square statistic with p-value, crude odds ratio (cOR) and adjusted odds ratio (aOR) with its 95% confidence interval (95% CI) were calculated. Results: When the dispenser of the medicine did not request the prescription from the user, the risk of non-responsible self-medication was very high (aOR=29.057). Additionally, going to the pharmaceutical establishment to ask for advice (aOR=1.884), eve...

Schinus molle is a medicinal plant used as an anti-inflammatory and for rheumatic pain in the traditional medicine of Peru. On the other hand, Aedes aegypti is the main vector of several tropical diseases and the transmitter of yellow fever, chikungunya, malaria, dengue, and Zika virus. In this study, the aim was to investigate the antioxidant activity in vitro and the insecticidal activity in silico, in the presence of the mosquito juvenile hormone-binding protein (mJHBP) from Aedes aegypti, of the essential oil from S. molle leaves. The volatile phytochemicals were analyzed by gas chromatography-mass spectrometry (GC-MS), and the profile antioxidants were examined by DPPH, ABTS, and FRAP assays. The evaluation in silico was carried out on mJHBP (PDB: 5V13) with an insecticidal approach. The results revealed that EO presented as the main volatile components to alpha-phellandrene (32.68%...