Objetivo: Analizar la relación entre índice de comorbilidad de Charlson (ICC) y la mortalidad en los pacientes hospitalizados por COVID-19. Metodología: Este fue un estudio retrospectivo y analítico, donde participaron un total de 320 pacientes hospitalizados diagnosticados con COVID-19 grave-crítico en un hospital de referencia de Lima, Perú 2020 - 2021. Se dividieron en 4 grupos de acuerdo con el ICC: 0, 1-2, 3-4, y ≥ 5. Se utilizó una regresión de Poisson con varianza robusta cruda para analizar la asociación entre el ICC y la mortalidad, y ajustada por sexo masculino, leucocitosis y dímero D. Resultados: De los 320 pacientes hospitalizados por COVID-19, 160 (50%) fallecieron. Las comorbilidades más frecuentes fueron hipertensión arterial 67 (21%) y diabetes mellitus 59 (18%). Se encontró una asociación estadísticamente significativa entre los grupos de ICC y la morta...

Objetivo: evaluar la sensibilidad y especificidad del test G8 en el tamizaje de adultos mayores con cáncer para la realización de la valoración geriátrica integral (VGI). Materiales y métodos: el presente estudio observacional y retrospectivo se realizó en el Servicio de Geriatría del Hospital Almenara de Lima, Perú. Se revisaron los informes de VGI en las historias clínicas electrónicos de adultos mayores (> 60 años) con cáncer, ambulatorios y hospitalizados, durante noviembre de 2022 y julio de 2023. Los pacientes se clasificaron según los criterios SIOG-1 (Sociedad Internacional de Oncología Geriátrica), formando dos grupos: pacientes aptos y pacientes no aptos o unfit (vulnerables + frágiles + muy enfermos). Del test G8 se estimó la sensibilidad, especificidad y valor predictivo positivo, área bajo la curva característica operativa del receptor (AUC). Resultados: i...

Objective: To evaluate sensitivity and specificity of the G8 test in screening older adults with cancer who may benefit from a Comprehensive Geriatric Assessment (CGA). Material and methods: This observational retrospective study was carried out in the Geriatrics Service of the Guillermo Almenara Hospital in Lima, Peru. CGA reports were reviewed in the electronic medical records of older adults (> 60 years) with cancer, both outpatients and inpatients, between November 2022 and July 2023. Patients were classified according to the SIOG-1 (International Society of Geriatric Oncology) criteria into two groups: fit and non-fit patients (vulnerable + frail + too sick). Sensitivity, specificity, and positive predictive value, area under the receiver operating characteristic curve (AUC), were estimated for the G8 test. Results: 201 patients entered the study, 91 women (45.3%) and 110 (54.7%)...

Objective: To evaluate sensitivity and specificity of the G8 test in screening older adults with cancer who may benefit from a Comprehensive Geriatric Assessment (CGA). Material and methods: This observational retrospective study was carried out in the Geriatrics Service of the Guillermo Almenara Hospital in Lima, Peru. CGA reports were reviewed in the electronic medical records of older adults (> 60 years) with cancer, both outpatients and inpatients, between November 2022 and July 2023. Patients were classified according to the SIOG-1 (International Society of Geriatric Oncology) criteria into two groups: fit and non-fit patients (vulnerable + frail + too sick). Sensitivity, specificity, and positive predictive value, area under the receiver operating characteristic curve (AUC), were estimated for the G8 test. Results: 201 patients entered the study, 91 women (45.3%) and 110 (54.7%)...

Objective: Malnutrition is common among cancer patients and even more prevalent in olderadults. Although its association with mortality risk is well established, further studies in LatinAmerica are needed to delve deeper into this relationship. This study aimed to evaluate theassociation between malnutrition and mortality risk among Peruvian older adult patients (≥ 60 years)with cancer. Materials and methods: Comprehensive geriatric assessment (CGA) records of olderadult patients with cancer evaluated at the Geriatrics Department of Hospital Almenara in Lima,Peru, from 2018 to January 2024, were reviewed. Nutritional status was assessed using the MiniNutritional Assessment Short Form (MNA-SF), which classifies patients into three groups: normal,at risk of malnutrition, or malnourished. This retrospective observational study comprised bothcases (patients at risk of malnutrition or malno...

Objective: To describe the clinical characteristics of drug-induced liver injury (DILI) in multidrug-resistant tuberculosis (MDR-TB) patients.Materials and methods: A retrospective study conducted in hospitalized patients with MDR-TB and DILI. The criteria of the DILI Expert Working Group were used for the diagnosis of DILI, and the RUCAM (Roussel Uclaf Causality AssessmentMethod) for the causality analysis. The specific association between DILI and antitubercular drugs was established by drug rechallenge or discontinuation and recovery. Results: Seven cases of MDR-TB and DILI are described in this research. The mean age (standard deviation) was 39.10 (3.30) years.Mean DILI occurred 30.40 (27.70) days after starting the treatment. Three (43.00 %) patients presented jaundice. Regarding the type of injury, four (57.00 %) had hepatocellular injury and three (43.00 %) cholestatic injury. Fou...