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artículo

Retrospective analysis of outcomes for pediatric acute lymphoblastic leukemia in South American centers

Publicado por
Duffy, C, Graetz, DE, Lopez, AMZ, Carrillo, A.K, Job, G, Chen, Y, Devidas, M, Leon, SA, Bonzi, SA, Flores, PC, Torres, LE, Broncano, EH, Jaramillo, SJ, Zelada, MO, Novoa, RR, Samudio, A, Sanchez-Fernandez, G, Villanueva, E, Metzger, ML, Friedrich, P, Jeha, S

Publicado 2023

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Introduction: Acute lymphoblastic Leukemia (ALL) is the most common pediatric malignancy. While the survival rate for childhood ALL exceeds 90% in high-income countries, the estimated survival in low-and middle-income countries ranges from 22-79%, depending on the region and local resources. Methods: This study retrospectively reviewed demographic, biological, and clinical parameters of children under 18 years of age with newly diagnosed ALL presenting between 2013-2017 across five pediatric centers in 4 countries in South America. Survival analyses were estimated using the Kaplan-Meier method. Results: Across the five centers, 752 patients were analyzed (Bolivia [N=9], Ecuador [N=221], Paraguay [N=197], Peru [N=325]) and 92.1% (n=690) patients were diagnosed with B-cell and 7.5% (n= 56) with T-cell ALL. The median age was 5.5 years old (IQR 7.29). At diagnosis, 47.8% of patients were ca...

artículo

Fortalecimiento de las políticas de salud pública contra el cáncer infantil: logros de Perú en el marco de la Iniciativa Mundial de la OMS contra el Cáncer Infantil

Publicado por
Maradiegue, E, Pascual, C, Vasquez, L, Maza, I, Ugaz, C, Montoya, J, Zapata, A, García, H, Chavez, S, Ordoñez, K, Rossi, J, Diaz, R, Morales, R, Trigoso, V, Ames, R, Celis, E, Barzola, I, Torres, L, Cosme, M, Tarrillo, F, Rojas, N, Santillan, C, Quispe, Y, Palacios, V, Godoy, V, Tello, M, Tarco, D, Wachtel, A, Malaver, E, Diaz, E, Goyburu, M, Perez, V, Talavera, I, Baca, ME, Maza M, Saldaña, L, Holguin, A, Jarquin, M, Loggetto, P, Metzger, M, Friedrich, P, Lam, C, Rodriguez-Galindo, C

Publicado 2023

Enlace

Objective. To report the progress in Peru, since June 2019, in the implementation of the World Health Organization Global Initiative for Childhood Cancer using the CureAll framework, which can be replicated in low- and middle-income countries. Methods. A mixed method was used of participatory and documentary evaluation. The participatory evaluation included stakeholders from various government institutions, nonprofit organizations, and international partners. The documentary aspect consisted of a review of data on the regulatory environment, national projects, and interventions implemented. The Ministry of Health engaged more than 150 participants to form working committees, which have developed policy and regulatory documents to strengthen care services. Results. Achievements include a decrease in the national treatment abandonment rate from 18.6% to 8.5%, the approval of the Childhood ...