Objective: Gallbladder cancer is a relatively uncommon neoplasm of the biliary system, characterized by a notably high mortality rate. Thisstudy aimed to identify prognostic factors for overall survival (OS) in Peruvian patients undergoing surgery for gallbladder cancer. Materials and methods: We conducted a retrospective cohortstudy of patientswith gallbladder carcinoma who underwent surgery at the Instituto Nacional de Enfermedades Neoplásicas between 2000 and 2020. OS was analyzed using the Kaplan–Meier method, and prognostic factors were identified using Cox proportional hazardsregressionmodels. Results: A total of 64 patientswere included. Themedian agewas 62 years, and 75%were female.Most patientswere diagnosed at stage T3 (37.5%), and 25% had M1 stage disease. Additionally, 51.6% of tumors were moderately differentiated, and 71.9% were of the adenocarcinoma histologic subtype. ...

Among the most frequent malignancies worldwide, hepatocellular carcinoma (HCC) is the second leading cause of cancer-related death (1). Its incidence has doubled over the past two decades, with the greatest burden occurring in low- and middle-income countries. Malignant primary liver tumors are usually described as a pathology affecting mainly men older than 40 years with a cirrhotic liver; they have rarely been reported in younger people and usually, in those younger than 40, most commonly hepatoblastoma.