The presence of secondary metabolites and of chromium element in seven medicinal plants empirically used for their hypoglycemic action by a phytochemical screening and a qualitative method and other one that is quantitative by Atomic Absorptioli. Spectroscopy for detelmining trivalent chromium has been researched. The studied species are: Phyllantus niruri L. (Chancapiedra), Geranium dielsianum Knut (Pasuchaca), GentianeIla alborosea G. (Hercampure), Otholobium pubescells (Culén), Smallantus sonchifolia (Yacón), Chloraphora tincoria (Mora) y Taraxacum officinalis W (Diente de león). It was phytochemically determined the presence of the following secondary metabolites: alkaloids, flavonoids , tannins, saponins and glycosides, by means of color and precipitation reagents. The determination of chromium element was carried out by qualitative and quantitative via. The accomplished study co...

The presence of secondary metabolites and of chromium element in seven medicinal plants empirically used for their hypoglycemic action by a phytochemical screening and a qualitative method and other one that is quantitative by Atomic Absorptioli. Spectroscopy for detelmining trivalent chromium has been researched. The studied species are: Phyllantus niruri L. (Chancapiedra), Geranium dielsianum Knut (Pasuchaca), GentianeIla alborosea G. (Hercampure), Otholobium pubescells (Culén), Smallantus sonchifolia (Yacón), Chloraphora tincoria (Mora) y Taraxacum officinalis W (Diente de león). It was phytochemically determined the presence of the following secondary metabolites: alkaloids, flavonoids , tannins, saponins and glycosides, by means of color and precipitation reagents. The determination of chromium element was carried out by qualitative and quantitative via. The accomplished study co...

The objective of the study was to elucidate the structure of the etanólic extract of the stem of Brunfelsia grandiflora D. Don and to evaluate its citotoxicity and the neuropathological effect on rat cerebellum. Obtained the extract the structural elucidation was made by Gas Chromatography/was made /Espectrometría of Masa (CG/EM), identifying the chemical components: Etil ester of vainíllic, octacosano, octadecan acid, palmític acid, 7 hidroxi-6-metoxi-cumarin, linoleate of ethyl and linoleic acid. The cytotoxic analysis was evaluated in embryos of Tetrapygus Niger black sea urchin, applying different concentrations of the extract. The evaluation of the neuropatológic effect of the etanólic extract in the rat cerebellum was made in 30 albino rats, Holtzmann strain, male stock, with corporal weight average of 250g approximately. For the study of the neuropatológic effect were admin...

Study objective was performing the structural elucidation of the essential oil of Ruta graveolens L. Ruda, determine its antioxidant activity and cytotoxicity testing. The complete plants were collected in Tarma, Region of Junin, and provided 1,80 kg of fresh leaves that were treated in a drag system with water vapor, obtaining performance of 0,3% v/p essential oil perfusion. The structural elucidation of chemical constituents of essential oil was performed by Gas Chromatography – Mass Spectrometry (GC-MS), stressing the identification of the following chemical components: 2-octanona 2-nonanona, nonanal, ciclohexen-5, 6-dietenil-1-methyl-, 2-decanona, nonyl ether, methyl 2-undecanona, ciclotetradecano, 2-dodecanona and 2-tridecanona. Evaluation of antioxidant activity in vitro of essential oil was made with the radical 2, 2-difenilpicrilhidrazil (DPPH) uptake method, demonstrating the ...

It was carried out the comparative evaluation of three synthetic drugs used as oral hypoglycemiants, against the aqueous obtained by infusion of leaves from Smallantus sonchifolius (Poepp) Rob. Yacon , using a experimental biomodel by hypoglycemia in normoglycemic rats of species Rattus norvegicus Var. Albine. The object of the research was to observe the 10 % aqueous extract effect of Smallantus sonchifolius (Poepp) Rob. Yacon in the decay of glycemia against glibenclamide, c1orprofamide and metformine drugs that have great usage in the treatment of type 2 diabetes mellitus (DM2). The vegetal material was collected in the Huancabamba district, province of Oxapampa in Cerro de Pasco department. The pharmaeological assay was taken with 36 female albine rats of Holtzman strain , with a average weight of 240g that were fed by a controlled foad and water ad libitum until the moment of experi...

The objective of the study was to elucidate the structure of the etanólic extract of the stem of Brunfelsia grandiflora D. Don and to evaluate its citotoxicity and the neuropathological effect on rat cerebellum. Obtained the extract the structural elucidation was made by Gas Chromatography/was made /Espectrometría of Masa (CG/EM), identifying the chemical components: Etil ester of vainíllic, octacosano, octadecan acid, palmític acid, 7 hidroxi-6-metoxi-cumarin, linoleate of ethyl and linoleic acid. The cytotoxic analysis was evaluated in embryos of Tetrapygus Niger black sea urchin, applying different concentrations of the extract. The evaluation of the neuropatológic effect of the etanólic extract in the rat cerebellum was made in 30 albino rats, Holtzmann strain, male stock, with corporal weight average of 250g approximately. For the study of the neuropatológic effect were admin...

Study objective was performing the structural elucidation of the essential oil of Ruta graveolens L. Ruda, determine its antioxidant activity and cytotoxicity testing. The complete plants were collected in Tarma, Region of Junin, and provided 1,80 kg of fresh leaves that were treated in a drag system with water vapor, obtaining performance of 0,3% v/p essential oil perfusion. The structural elucidation of chemical constituents of essential oil was performed by Gas Chromatography – Mass Spectrometry (GC-MS), stressing the identification of the following chemical components: 2-octanona 2-nonanona, nonanal, ciclohexen-5, 6-dietenil-1-methyl-, 2-decanona, nonyl ether, methyl 2-undecanona, ciclotetradecano, 2-dodecanona and 2-tridecanona. Evaluation of antioxidant activity in vitro of essential oil was made with the radical 2, 2-difenilpicrilhidrazil (DPPH) uptake method, demonstrating the ...

Se realizó 1a evaluación comparativa de tres fármacos de síntesis utilizados como hipoglicemiantes orales con el extracto acuoso obtenido por infusión de las hojas de Smallanthus sochifolíuS (Poepp) Rob. "yacón", utilizando un biomodelo experimental por hiperglicemia en ratas normoglucémicas de la especie Rattus norvegicus var. Albina. El objetivo de la investigación fue observar el efecto del extracto acuoso al 10% de las hojas de "yacón" en el descenso de la glicemia frente a la glibenclamida, clorpropamida y metformina, que tienen amplio uso en el tratamiento de la diabetes mellitus tipo 2 (DM2). El material vegetal fue colectado en el distrito de Huancabamba provincia de Oxapampa del departamento de Cerro de Pasco. El ensayo farmacológico se realizó con 36 ratas albinas hembras, cepa Holtzman con un peso promedio de 240 g, que estuvieron sometidas a una alimentación cont...

The study aimed to analyze the chemical composition of the essential oil from leaves of Petroselinum crispum (Mill) Nyman ex A.W. Hill "perejil" and determine antibacterial activity. Essential oil was obtained treating 20 kg of fresh leaves with a distillation equipment by dragging with steam; obtaining performance of 0,02 per cent and four milliliters of oil v/p. In the qualitative analysis was analyzed its solubility in organic solvents, and chemical components were determined by gas chromatography / mass spectrometry (GC/MS), achieving the elucidation of the following compounds: 1R-α-pinene, β-pinene, β-phellandrene, p,α-dimethyl estirene, (E)-2-caren-4-ol, 1,3-benzodioxol-(2-propenil) 4-metoxy-6, 1,3-benzodioxol, 4,7-dimetoxy-5-(2-propenil)-. In vitro bacterial activity determination was made by the method of diffusion in agar, demonstrating significant activity to Staphylococcus...

Industrial effluents without treatment or supervision by the authorities pollute the environment. Solving the problem does not go only by the control, supervision and penalties for companies that generate effluents, require its own investigation as well as develop specific treatments, accessible and affordable that can be adopted by each industry. The primary treatment is removal by physical or chemical means a substantial part of sedimentable or floating material, reducing an important fraction of the organic load, which represents a significant percentage of solid contaminants. Within the types of primary treatment quote coagulation and flocculation. The main objective was to evaluate the efficacy of two coagulants in reducing the pollution potential of effluents from the fruit processing plant. To make the primary treatment: were assayed two chemical substances, aluminum sulfate as in...

A study of the essential oil extracted from the leaves and flowers of the Thymus vulgris L. ''Tomillo'' by stearn distillation method was carried out. Samples were determined by physico-chemical analyses and chemical composition was obtained by GC/MS mass spectrophotometer coupled to gaschromatographer, determining the following hydrocarbonated compounds like: Thujene; 1,3,6 Octatriene,3,7-Dimethyl; Camphene; Beta Myrcene; Delta 4 Carena; Beta Selinene; Delta Cadinene; Benzene 1 methyl, 4 (l-methyl ethyl); Gama Terpinene; Trans Caryophyllene; Germacrene D.; Trans Caryophyllene; Beta Bisabolene y compuesto oxigenados como: 7 octen, 401 (CAS); l.6 octadien, 3 0l, 3,7 Dimethyl Acetate; Linalool; Isoborneol; carvacrol; Thymol; Farnesyl acetate 2.At the same time, antimicrobial activity was determined against pathogenic strains from clinical samples and from ATCC (American Typical Cultivate C...

The properties of Annona muricata L. (guanabana) have been demonstrated in studies carried out on the its leaves, pulp, seeds, stems and fruit peel; highlighting in each of them its antioxidant properties. In the present work the quantification of the total polyphenols and the evaluation of the antioxidant capacity in the ethanolic extract of the flowers of Annona muricata L. (guanabana) was carried out. The flowers samples were collected in the province of Jaen (Cajamarca, Peru). The ethanolic extract was obtained by maceration of the pulverized dried flowers. The quantification of the polyphenols in the ethanolic extract of the flowers was carried out using the Folin-Ciocalteu technique using gallic acid as a pattern. The evaluation of the antioxidant capacity was carried out using the methods of capturing the radical’s DPPH and ABTS. + using the Trolox as a pattern for both methods....

The study aimed to analyze the chemical composition of the essential oil from leaves of Petroselinum crispum (Mill) Nyman ex A.W. Hill "perejil" and determine antibacterial activity. Essential oil was obtained treating 20 kg of fresh leaves with a distillation equipment by dragging with steam; obtaining performance of 0,02 per cent and four milliliters of oil v/p. In the qualitative analysis was analyzed its solubility in organic solvents, and chemical components were determined by gas chromatography / mass spectrometry (GC/MS), achieving the elucidation of the following compounds: 1R-α-pinene, β-pinene, β-phellandrene, p,α-dimethyl estirene, (E)-2-caren-4-ol, 1,3-benzodioxol-(2-propenil) 4-metoxy-6, 1,3-benzodioxol, 4,7-dimetoxy-5-(2-propenil)-. In vitro bacterial activity determination was made by the method of diffusion in agar, demonstrating significant activity to Staphylococcus...

Industrial effluents without treatment or supervision by the authorities pollute the environment. Solving the problem does not go only by the control, supervision and penalties for companies that generate effluents, require its own investigation as well as develop specific treatments, accessible and affordable that can be adopted by each industry. The primary treatment is removal by physical or chemical means a substantial part of sedimentable or floating material, reducing an important fraction of the organic load, which represents a significant percentage of solid contaminants. Within the types of primary treatment quote coagulation and flocculation. The main objective was to evaluate the efficacy of two coagulants in reducing the pollution potential of effluents from the fruit processing plant. To make the primary treatment: were assayed two chemical substances, aluminum sulfate as in...

A study of the essential oil extracted from the leaves and flowers of the Thymus vulgris L. ''Tomillo'' by stearn distillation method was carried out. Samples were determined by physico-chemical analyses and chemical composition was obtained by GC/MS mass spectrophotometer coupled to gaschromatographer, determining the following hydrocarbonated compounds like: Thujene; 1,3,6 Octatriene,3,7-Dimethyl; Camphene; Beta Myrcene; Delta 4 Carena; Beta Selinene; Delta Cadinene; Benzene 1 methyl, 4 (l-methyl ethyl); Gama Terpinene; Trans Caryophyllene; Germacrene D.; Trans Caryophyllene; Beta Bisabolene y compuesto oxigenados como: 7 octen, 401 (CAS); l.6 octadien, 3 0l, 3,7 Dimethyl Acetate; Linalool; Isoborneol; carvacrol; Thymol; Farnesyl acetate 2.At the same time, antimicrobial activity was determined against pathogenic strains from clinical samples and from ATCC (American Typical Cultivate C...

In the present investigation a phitochemical study of Prezia multiflora(H et B) lees Escorsonera was accomplished in order to determine the presence of secondary metabolites. A botanic study of this specie has been made to indicate its systematic location and morfhological description.A chemical and pharmacological review of the mayor components, as flavonoids and alcaloids; has also been performed. TLC and preparative chromatography were done, ending with the separation of two flavonoids. The identification of the flavonoid (flavonone type) as 7-O-RHAMNOGLUCOSIDE-3',5- DIHYDROXY -4'METOXYFLAVANONE, was done by UV spectroscopy. The other one probably would be: 3',5,7-TRIDIHYDROXY -4' -METOXYFLAVANONE. Two alcaloids were also identified and their probable structure would be: 1,4-(1,3-PIPERIDIL-DIENO)-2,5-0XO-6-HYDROXY-2H,3H-INDOL-ETENO and 1,4-(1,3-PIPERIDIL-DIENO)-2,5-0XO-6-0-GLUCOSYL-2H...

In the present investigation a phitochemical study of Prezia multiflora(H et B) lees Escorsonera was accomplished in order to determine the presence of secondary metabolites. A botanic study of this specie has been made to indicate its systematic location and morfhological description.A chemical and pharmacological review of the mayor components, as flavonoids and alcaloids; has also been performed. TLC and preparative chromatography were done, ending with the separation of two flavonoids. The identification of the flavonoid (flavonone type) as 7-O-RHAMNOGLUCOSIDE-3',5- DIHYDROXY -4'METOXYFLAVANONE, was done by UV spectroscopy. The other one probably would be: 3',5,7-TRIDIHYDROXY -4' -METOXYFLAVANONE. Two alcaloids were also identified and their probable structure would be: 1,4-(1,3-PIPERIDIL-DIENO)-2,5-0XO-6-HYDROXY-2H,3H-INDOL-ETENO and 1,4-(1,3-PIPERIDIL-DIENO)-2,5-0XO-6-0-GLUCOSYL-2H...

The present research was aimed to determine qualitatively the chemical constituents and antibacterial, antifungal and antioxidant activity of essential oil from leaves of Tagetes elliptica Smith “chincho”, native of the province of Huaraz, Ancash region, which was obtained by the method of distillation with water vapor. Later physicochemical constants were determined, and then made the determination of chemical composition by Gas Chromatography / Mass Spectrometry (GC/MS). By the methods of agar diffusion and agar dilution were determined antimicrobial activities and minimum inhibitory concentration (MIC), respectively, against the following microorganisms: S. aureus ATCC 25933, S. epidermidis (clinical isolate), B. subtilis (environmental strain), E. coli (clinical isolate), P. aeruginosa ATCC 27853, Klebsiella (clinical isolate) and C. albicans ATCC 10231. In tests, the essential o...

The present research was aimed to determine qualitatively the chemical constituents and antibacterial, antifungal and antioxidant activity of essential oil from leaves of Tagetes elliptica Smith “chincho”, native of the province of Huaraz, Ancash region, which was obtained by the method of distillation with water vapor. Later physicochemical constants were determined, and then made the determination of chemical composition by Gas Chromatography / Mass Spectrometry (GC/MS). By the methods of agar diffusion and agar dilution were determined antimicrobial activities and minimum inhibitory concentration (MIC), respectively, against the following microorganisms: S. aureus ATCC 25933, S. epidermidis (clinical isolate), B. subtilis (environmental strain), E. coli (clinical isolate), P. aeruginosa ATCC 27853, Klebsiella (clinical isolate) and C. albicans ATCC 10231. In tests, the essential o...