El objetivo del estudio es conocer el patrón de resistencia actual de Candida auris en cultivos obtenidos de pacientes admitidos a unidades de cuidados intensivos del Hospital Guillermo Almenara Irigoyen, tomando en consideración que es el primer hospital con aislamientos confirmados en Perú. Tipo de estudio observacional, descriptivo y transversal. Población de estudio incluirá a todos los pacientes admitidos a servicios de cuidados intensivos, médicos y quirúrgicos, del Hospital Nacional Guillermo Almenara Irigoyen, periodo noviembre 2022 – abril 2023; que además presenten aislamiento positivo a Candida auris. Se empleará una ficha de recolección de datos generales elaborada para este estudio, posteriormente se procederá a identificación por perfil fenotípico y sistema automatizado. Para el análisis estadístico se utilizará el programa STATA, junto a un análisis univ...

Introducción: Las enterobacterias productoras de carbapenemasas (EPC) representan un problema de salud pública y cada vez hay más reportes de infecciones sistémicas asociadas con la carbapenemasa OXA-48 en America Latina. Presentamos los primeros 2 casos de infecciones sistémicas por Klebsiella pneumoniae productora de OXA-48 en Perú. Se observó una respuesta clínica favorable luego del tratamiento dirigido con colistina como base.

Background:Carbapenemase-producing Enterobacteriaceae(CPE) represents a global public health concern and systemic infections associated with OXA-48 carbapenemase are in creasingly being reported in Latin America. Here, we present the first 2 cases of systemic infections by OXA-48-Producing Klebsiellapneumoniae in Peru. A favor able clinical response was observed after targeted treatment with colistin as a backbone.

Background: Carbapenemase-producing Enterobacteriaceae (CPE) represents a global public health concern and systemic infections associated with OXA-48 carbapenemase are increasingly being reported in Latin America. Here, we present the first 2 cases of systemic infections by OXA-48-Producing Klebsiella pneumoniae in Peru. A favorable clinical response was observed after targeted treatment with colistin as a backbone.

Objetivo: Diseñar y validar un instrumento para evaluar el nivel de conocimientos sobre Depresión mayor en médicos de atención primaria en Chiclayo. Material y Métodos: Estudio descriptivo, trasversal, tipo validación de un instrumento. El primer constructo se desarrolló en el 2010 en base al marco teórico y sometido a juicio de expertos. En el 2011 nuevamente se sometió el cuestionario a 12 expertos según la metodología Delphi, obteniéndose un constructo de 14 preguntas: 7 de diagnóstico y 7 de tratamiento; se realizó un estudio piloto para evaluar la inteligibilidad y pertinencia del instrumento. Se evaluó la confiabilidad con el coeficiente de Kuder-Richardson y el Alfa de Cronbach. La validez de constructo se realizó mediante análisis factorial. Se utilizó SPSS v. 15. Resultados: Se entrevistaron 34 médicos generales (90%) y 6 alumnos (10%) que habían terminado el...

Acinetobacter baumannii has been described as a cause of serious community-acquired infections in tropical countries. Currently, its implications when simultaneously identified with other pathogens are not yet adequately understood. A descriptive study was conducted on hospitalized patients with a diagnosis of moderate/severe SARS-CoV-2-induced pneumonia confirmed via real-time RT-PCR. Patients aged > 18 years who were admitted to a specialized COVID-19 treatment center in Peru were selected for enrollment. A. baumannii was detected via the PCR amplification of the blaOXA-51 gene obtained from nasopharyngeal swabs within 48 h of hospitalization. A total of 295 patients with COVID-19 who met the study inclusion criteria were enrolled. A. baumannii was simultaneously identified in 40/295 (13.5%) of COVID-19-hospitalized patients. Demographic data and comorbidities were comparable in both A...

The impact of respiratory coinfections in COVID-19 is still not well understood despite the growing evidence that consider coinfections greater than expected. A total of 295 patients older than 18 years of age, hospitalized with a confirmed diagnosis of moderate/severe pneumonia due to SARSCoV-2 infection (according to definitions established by the Ministry of Health of Peru) were enrolled during the study period. A coinfection with one or more respiratory pathogens was detected in 154 (52.2%) patients at hospital admission. The most common coinfections were Mycoplasma pneumoniae (28.1%), Chlamydia pneumoniae (8.8%) and with both bacteria (11.5%); followed by Adenovirus (1.7%), Mycoplasma pneumoniae/Adenovirus (0.7%), Chlamydia pneumoniae/Adenovirus (0.7%), RSVB/Chlamydia pneumoniae (0.3%) and Mycoplasma pneumoniae/Chlamydia pneumoniae/Adenovirus (0.3%). Expectoration was less frequent ...

The impact of respiratory coinfections in COVID-19 is still not well understood despite the growing evidence that consider coinfections greater than expected. A total of 295 patients older than 18 years of age, hospitalized with a confirmed diagnosis of moderate/severe pneumonia due to SARS-CoV-2 infection (according to definitions established by the Ministry of Health of Peru) were enrolled during the study period. A coinfection with one or more respiratory pathogens was detected in 154 (52.2%) patients at hospital admission. The most common coinfections were Mycoplasma pneumoniae (28.1%), Chlamydia pneumoniae (8.8%) and with both bacteria (11.5%); followed by Adenovirus (1.7%), Mycoplasma pneumoniae/Adenovirus (0.7%), Chlamydia pneumoniae/Adenovirus (0.7%), RSV-B/Chlamydia pneumoniae (0.3%) and Mycoplasma pneumoniae/Chlamydia pneumoniae/Adenovirus (0.3%). Expectoration was less frequen...