Objectives: To determine the rate of optimal cytoreduction in patients with advanced ovarian cancer who received neoadjuvant chemotherapy with dose-dense carboplatin and paclitaxel followed by interval debulking surgery (IDS). Materials and methods: A retrospective study of a series of cases of Peruvian women treated with neoadjuvant chemotherapy with carboplatin (6 AUC mg/mL/min) and paclitaxel (80 mg/m2 weekly) followed by IDS, at the National Institute of Neoplastic Diseases during the 2010-2014 period. Results: The 41 patients who made it to the interval surgery had a median age of 59 years (range: 47-73 years). In 37 (90.2%) patients, high-grade serous adenocarcinoma histology was reported. Thirty-four (82.9%) achieved optimal cytoreduction and five (14.7%), a complete pathological response. Progression-free survival at one year and two years was 74.7% and 51.8%, respectively. Overa...

Industrial effluents without treatment or supervision by the authorities pollute the environment. Solving the problem does not go only by the control, supervision and penalties for companies that generate effluents, require its own investigation as well as develop specific treatments, accessible and affordable that can be adopted by each industry. The primary treatment is removal by physical or chemical means a substantial part of sedimentable or floating material, reducing an important fraction of the organic load, which represents a significant percentage of solid contaminants. Within the types of primary treatment quote coagulation and flocculation. The main objective was to evaluate the efficacy of two coagulants in reducing the pollution potential of effluents from the fruit processing plant. To make the primary treatment: were assayed two chemical substances, aluminum sulfate as in...

El control y tratamiento biológico de los contaminantes requiere de microorganismos adaptados a condiciones extremas con capacidades enzimáticas especiales, razón por la cual se buscan microorganismos aislados de diversas fuentes naturales que presenten dicho potencial biotecnológico. El presente trabajo se basa en el aislamiento de microorganismos de un ambiente árido y altamente salino ubicadas en las zonas costeras de la capital del país. El aislamiento dio como resultado una gran variedad de formas (bacilos, cocos) y grupos microbianos (bacterias, hongos, actinomicetos) tolerantes a niveles bajos de actividad de agua, que al ser evaluados enzimáticamente presentaron importantes capacidades amilolíticas, proteolíticas y lipolíticas, potencialmente aplicables en el tratamiento de contaminantes; dando a conocer la gran importancia de la bioprospección microbiana.

Industrial effluents without treatment or supervision by the authorities pollute the environment. Solving the problem does not go only by the control, supervision and penalties for companies that generate effluents, require its own investigation as well as develop specific treatments, accessible and affordable that can be adopted by each industry. The primary treatment is removal by physical or chemical means a substantial part of sedimentable or floating material, reducing an important fraction of the organic load, which represents a significant percentage of solid contaminants. Within the types of primary treatment quote coagulation and flocculation. The main objective was to evaluate the efficacy of two coagulants in reducing the pollution potential of effluents from the fruit processing plant. To make the primary treatment: were assayed two chemical substances, aluminum sulfate as in...

El control y tratamiento biológico de los contaminantes requiere de microorganismos adaptados a condiciones extremas con capacidades enzimáticas especiales, razón por la cual se buscan microorganismos aislados de diversas fuentes naturales que presenten dicho potencial biotecnológico. El presente trabajo se basa en el aislamiento de microorganismos de un ambiente árido y altamente salino ubicadas en las zonas costeras de la capital del país. El aislamiento dio como resultado una gran variedad de formas (bacilos, cocos) y grupos microbianos (bacterias, hongos, actinomicetos) tolerantes a niveles bajos de actividad de agua, que al ser evaluados enzimáticamente presentaron importantes capacidades amilolíticas, proteolíticas y lipolíticas, potencialmente aplicables en el tratamiento de contaminantes; dando a conocer la gran importancia de la bioprospección microbiana.

El control y tratamiento biológico de los contaminantes requiere de microorganismos adaptados a condiciones extremas con capacidades enzimáticas especiales, razón por la cual se buscan microorganismos aislados de diversas fuentes naturales que presenten dicho potencial biotecnológico. El presente trabajo se basa en el aislamiento de microorganismos de un ambiente árido y altamente salino ubicadas en las zonas costeras de la capital del país. El aislamiento dio como resultado una gran variedad de formas (bacilos, cocos) y grupos microbianos (bacterias, hongos, actinomicetos) tolerantes a niveles bajos de actividad de agua, que al ser evaluados enzimáticamente presentaron importantes capacidades amilolíticas, proteolíticas y lipolíticas, potencialmente aplicables en el tratamiento de contaminantes; dando a conocer la gran importancia de la bioprospección microbiana.

Objective.: To determine the frequency and prognostic value of anemia in cancer patients receiving care at the National Institute of Neoplastic Diseases (Instituto Nacional de Enfermedades Neoplásicas - INEN) between January and April of 2010. Materials and methods.: Anemia was considered for men with hemoglobin levels at <13 g/dL; and for women, at <12 g/dL. Associations between qualitative features were assessed with a Chi-square test. Kaplan-Meier estimator was used for the analysis of the survival curves, and differences between the curves were performed with the log-rank test. Results.: 772 patients were included; 584 (75.7%) had solid tumors and 188 (24.3%) had hematologic malignancies. Anemia was diagnosed in 359 patients (46.5%); hematologic malignancies in 127 patients (67.6%); and solid neoplasms in 235 (40.2%). Hematologic malignancies with the highest frequency of anemia wer...

Los autores reflexionan acerca de las posibles alternaciones que el personal sanitario puede experimentar al tratar con pacientes en áreas de cuidado crítico por COVID-19.

The biological control of pests & mites on peruvian agriculture was characterized by the intensive use of chemical pesticides. However, the decrease on yield and the emergence of resistance to pesticides have obligated to farmers to increase chemical pesticide use for plague control. This has caused environmental pollution, benefical insects death, persistence chemicals residues on fruits, acute and chronic toxicity risks, moreover an increase on production costs. The objectives of this research were to isolate and to characterize B. thuringiensis native strains, and) to evaluate entomotoxic potential against Spodoptera frugiperda. Were isolated 54 natives strains of Bacillus thuringiensis from peruvian agricultural soils. Microscopic morphology showed parasporal crystals characteristic of B. thuringiensis diversity. The strains were evaluated and confirmed with biochemistry and grow...

The biological control of pests & mites on peruvian agriculture was characterized by the intensive use of chemical pesticides. However, the decrease on yield and the emergence of resistance to pesticides have obligated to farmers to increase chemical pesticide use for plague control. This has caused environmental pollution, benefical insects death, persistence chemicals residues on fruits, acute and chronic toxicity risks, moreover an increase on production costs. The objectives of this research were to isolate and to characterize B. thuringiensis native strains, and) to evaluate entomotoxic potential against Spodoptera frugiperda. Were isolated 54 natives strains of Bacillus thuringiensis from peruvian agricultural soils. Microscopic morphology showed parasporal crystals characteristic of B. thuringiensis diversity. The strains were evaluated and confirmed with biochemistry and grow...