1
2
artículo
Publicado 2003
Enlace
Enlace
La toma de decisiones en el área de emergencia, dada su implicancia ele atención a pacientes en estado de riesgo, es sumamente sensible. Una decisión inadecuada puede hacer la diferencia entre la vida y la muerte. El sistema debe responder rápida, eficiente y eficazmente, y el factor humano médico juega el papel protagonista. Se puede concluir entonces, que la adecuada distribución del potencial humano disponible en el momento de la emergencia, es determinante para brindar una atención adecuada al paciente. En este trabajo se presenta, un modelo que estima las configuraciones adecuadas de los equipos médicos en el área de emergencia, basado en parámetros medidos cuantitativamente por simulación, los cuales son utilizados para estimar la calidad de la atención. Estos parámetros respaldan a cada uno de los requerimientos de la respuesta. Se tienen parámetros basados en el con...
3
artículo
Publicado 2018
Enlace
Enlace
Decision making in the emergency area, given its implication of caring for patients at risk, is extremely sensitive. An inappropriate decision canmake the difference between life and death. The system must respond quickly, efficiently and effectively, and the medical human factor plays the leading role. It can be concluded then that the adequate distribution of the human potential available at the time of emergency is decisive in providing adequate care to the patient. In this work, a model is presented that estimates the appropriate configurations ofmedical equipment in the emergency area, based on parameters measured quantitatively by simulation, which are used to estimate the quality ofthe attention. These parameters support each of the response requirements. There are parameters based on the control of response time, toensure speed of care according to the patient's urgency. In addit...
4
artículo
Publicado 2020
Enlace
Enlace
The aim of his study was to determine the zoometric indexes of the Creole sheep of the Chuquibambilla Experimental Centre, in Puno, Peru. The study was carried out on a population of 380 female creole sheep older than two years. Various indices were calculated, including ethnological: cephalic index (CI), thoracic index (IT), body index (ICO), pelvic index (IP); milk capacity indices: thoracic metacarpal index (IDT), costal metacarpal index (IDC); meat capacity indexes: relative proportionality index of the thorax (IPRT), transverse pelvic index (IPT), longitudinal pelvic index (IPL), as well as the relative cane thickness (ERC). The results show that the Creole sheep presents characteristics of mesocephalic, brevilinear, convexylline and eumometric animals, with aptitude to develop muscular tissue, easy of calving and adaptation.
5
artículo
Publicado 2020
Enlace
Enlace
The aim of his study was to determine the zoometric indexes of the Creole sheep of the Chuquibambilla Experimental Centre, in Puno, Peru. The study was carried out on a population of 380 female creole sheep older than two years. Various indices were calculated, including ethnological: cephalic index (CI), thoracic index (IT), body index (ICO), pelvic index (IP); milk capacity indices: thoracic metacarpal index (IDT), costal metacarpal index (IDC); meat capacity indexes: relative proportionality index of the thorax (IPRT), transverse pelvic index (IPT), longitudinal pelvic index (IPL), as well as the relative cane thickness (ERC). The results show that the Creole sheep presents characteristics of mesocephalic, brevilinear, convexylline and eumometric animals, with aptitude to develop muscular tissue, easy of calving and adaptation.
6
artículo
Publicado 2021
Enlace
Enlace
Xanthates are widely used in mining industry as collectors for its high affinity towards metal sulfides and precious metal ores. The possibility of using alginate for xanthation has not been explored yet despite the feasibility by the presence of hydroxyl groups alongside the polymeric chains. Therefore, this work aims to evaluate the alginate as a matrix for xanthation and its application on heavy metal ions removal. In order to obtain green materials, important pararmeter were explored such as the effect of reaction time (4–12 h), type of base (NaOH/KOH) and amount of carbon disulfide (2–10%v/v). Xanthated alginates were analyzed by NMR techniques and evidence of β-elimination was detected at 5.45 ppm. Furthermore, the presence of S element was confirmed by EDS mapping technique, while XRD showed a semi-crystalline structure. On the other hand, the chemical shifts of δ(C=S) and ...
7
artículo
Real-world outcomes of anti-EGFR therapy in advanced non–small cell lung cancer EGFR mutated in Peru
Publicado 2023
Enlace
Enlace
Background: Despite the advances in the management of advanced non–small cell lung cancer (NSCLC), the access to genetic profiling and target therapies remains a challenge in Latin America, even in countries with a higher rate of targetable mutations. The aim of this study is to evaluate the clinical outcomes of anti-epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI) treatment in a Peruvian real-world setting. Methods: This is a retrospective study of recurrent or advanced NSCLC EGFR mutated patients diagnosed and treated with anti-EGFR TKI at Instituto Nacional de Enfermedades Neoplásicas (INEN) between January 1, 2015 to December 31, 2020. The outcomes were objective response rate (ORR), progression free survival (PFS), and overall survival (OS). Results: We identify 613 stage IV or recurrent NSCLC patients who were tested for EGFR mutations and found a pathoge...
8
artículo
Publicado 2021
Enlace
Enlace
The aim of this study was to evaluate the superovulatory and embryonic response in alpacas with equine chorionic gonadotropin (eCG) according to the number of follicles recruited >3 mm in the follicular wave (FW). Twenty-six alpacas from the CIP “Chuquibambilla”, Universidad Nacional del Altiplano, Puno, Peru, were selected and distributed into two experimental groups: GE01 (n=15 alpacas) with less than three follicles >3 mm and GE02 (n=11 alpacas) with more from four follicles >3 mm in diameter to follicular recruitment post-induction of ovulation by a follicle >7 mm with 0.0042 mg of buserelin acetate (BA). Both groups were evaluated by ultrasound every other day until the beginning of the third follicular wave. Subsequently, females with follicles >7 mm were induced to ovulate with BA (day 0), ovulation was verified at 36 h and 700 IU of eCG was administered. On day...
9
artículo
Publicado 2021
Enlace
Enlace
The aim of this study was to evaluate the superovulatory and embryonic response in alpacas with equine chorionic gonadotropin (eCG) according to the number of follicles recruited >3 mm in the follicular wave (FW). Twenty-six alpacas from the CIP “Chuquibambilla”, Universidad Nacional del Altiplano, Puno, Peru, were selected and distributed into two experimental groups: GE01 (n=15 alpacas) with less than three follicles >3 mm and GE02 (n=11 alpacas) with more from four follicles >3 mm in diameter to follicular recruitment post-induction of ovulation by a follicle >7 mm with 0.0042 mg of buserelin acetate (BA). Both groups were evaluated by ultrasound every other day until the beginning of the third follicular wave. Subsequently, females with follicles >7 mm were induced to ovulate with BA (day 0), ovulation was verified at 36 h and 700 IU of eCG was administered. On day...
10
artículo
Publicado 2018
Enlace
Enlace
Objectives: To determine the rate of optimal cytoreduction in patients with advanced ovarian cancer who received neoadjuvant chemotherapy with dose-dense carboplatin and paclitaxel followed by interval debulking surgery (IDS). Materials and methods: A retrospective study of a series of cases of Peruvian women treated with neoadjuvant chemotherapy with carboplatin (6 AUC mg/mL/min) and paclitaxel (80 mg/m2 weekly) followed by IDS, at the National Institute of Neoplastic Diseases during the 2010-2014 period. Results: The 41 patients who made it to the interval surgery had a median age of 59 years (range: 47-73 years). In 37 (90.2%) patients, high-grade serous adenocarcinoma histology was reported. Thirty-four (82.9%) achieved optimal cytoreduction and five (14.7%), a complete pathological response. Progression-free survival at one year and two years was 74.7% and 51.8%, respectively. Overa...