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1
artículo
The purpose of the present work is to determine the quality of five bodies of water within the Rimac river watershed, by analyzing the data provided by the Autoridad Nacional del Agua (ANA ‐ the National Water Authority) in its report on Technical Monitoring of Water Quality in the Rimac River Watershed (2013). These five bodies of water have been assigned to Category 1 A2 ("Domestic and Recreational Use") indicating that their water could be made potable through conventional treatment. The results can be used as a tool to evaluate the quality of bodies of water and facilitate their environmental management, by identifying those would be more prone to lose their qualification as Category 1 A2. Use of the Grey Clustering Analysis methodology and the Prati water quality index allowed us to carry out the analysis in an objective manner. The criteria for selecting the bodies of water was t...
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artículo
El presente trabajo tiene como finalidad determinar la calidad de cinco cuerpos de agua de la Cuenca del Río Rímac los cuales pertenecen a la Categoría 1 A2: " Poblacional y Recreacional" Aguas que pueden ser potabilizadas con tratamiento convencional, mediante el análisis de datos que la Autoridad Nacional del Agua ANA proporcionó en su informe de Técnico de Monitoreo de la Calidad del Agua en la Cuenca del Río Rímac en el año 2013, con la finalidad de brindar una herramienta que cuantifique la calidad de los cuerpos de agua y facilite la toma de decisiones en la gestión ambiental de estos mediante la identificación de aquel que sea más propenso a la pérdida de su calidad como Categoría 1 A2. La aplicación de la metodología de Análisis de Grey Clustering y el Índice de la calidad de agua de Prati, permitieron realizar el análisis de forma objetiva, el criterio para la...
3
artículo
The purpose of the present work is to determine the quality of five bodies of water within the Rimac river watershed, by analyzing the data provided by the Autoridad Nacional del Agua (ANA ‐ the National Water Authority) in its report on Technical Monitoring of Water Quality in the Rimac River Watershed (2013). These five bodies of water have been assigned to Category 1 A2 ("Domestic and Recreational Use") indicating that their water could be made potable through conventional treatment. The results can be used as a tool to evaluate the quality of bodies of water and facilitate their environmental management, by identifying those would be more prone to lose their qualification as Category 1 A2. Use of the Grey Clustering Analysis methodology and the Prati water quality index allowed us to carry out the analysis in an objective manner. The criteria for selecting the bodies of water was t...
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informe técnico
Proyecto Reforestación en las zonas altas del Perú, CIID - Canada/Ministerio de Agricultura - Perú
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artículo
Malaria in Peru, dominated by Plasmodium vivax, remains a public health problem. The 1990s saw newly epidemic malaria emerge, primarily in the Loreto Department in the Amazon region, including areas near to Iquitos, the capital city, but sporadic malaria transmission also occurred in the 1990s-2000s in both north-coastal Peru and the gold mining regions of southeastern Peru. Although a Global Fund-supported intervention (PAMAFRO, 2005-2010) was temporally associated with a decrease of malaria transmission, from 2012 to the present, both P. Vivax and Plasmodium falciparum malaria cases have rapidly increased. The Peruvian Ministry of Health continues to provide artemesininbased combination therapy for microscopy-confirmed cases of P. Falciparum and chloroquine-primaquine for P. Vivax. Malaria transmission continues in remote areas nonetheless, where the mobility of humans and parasites fa...
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artículo
In this manuscript we report the flag-dipole spinors dual structure direct definition and analyze the properties behind the corresponding operator which generates such structure. This particular construction may be interesting for cosmological, phenomenological and mathematical physics applications. In addition, we analyse the behaviour of the flag-dipole spinors under action of discrete symmetries, facing an unconventional property encoded on (CPT)2.
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This is the first study to assess the risk of co-endemic Plasmodium vivax and Plasmodium falciparum transmission in the Peruvian Amazon using boosted regression tree (BRT) models based on social and environmental predictors derived from satellite imagery and data. Yearly cross-validated BRT models were created to discriminate high-risk (annual parasite index API > 10 cases/1000 people) and very-high-risk for malaria (API > 50 cases/1000 people) in 2766 georeferenced villages of Loreto department, between 2010–2017 as other parts in the article (graphs, tables, and texts). Predictors were cumulative annual rainfall, forest coverage, annual forest loss, annual mean land surface temperature, normalized difference vegetation index (NDVI), normalized difference water index (NDWI), shortest distance to rivers, time to populated villages, and population density. BRT models built with predicto...
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artículo
Malaria has steadily increased in the Peruvian Amazon over the last five years. This study aimed to determine the parasite prevalence and micro-geographical heterogeneity of Plasmodium vivax parasitaemia in communities of the Peruvian Amazon. Four cross-sectional active case detection surveys were conducted between May and July 2015 in four riverine communities in Mazan district. Analysis of 2785 samples of 820 individuals nested within 154 households for Plasmodium parasitaemia was carried out using light microscopy and qPCR. The spatio-temporal distribution of Plasmodium parasitaemia, dominated by P. vivax, was shown to cluster at both household and community levels. Of enrolled individuals, 47% had at least one P. vivax parasitaemia and 10% P. falciparum, by qPCR, both of which were predominantly sub-microscopic and asymptomatic. Spatial analysis detected significant clustering in thr...
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artículo
The measurement of recent malaria exposure can support malaria control efforts. This study evaluated serological responses to an in-house Plasmodium vivax Merozoite Surface Protein 8 (PvMSP8) expressed in a Baculovirus system as sero-marker of recent exposure to P. vivax (Pv) in the Peruvian Amazon. In a first evaluation, IgGs against PvMSP8 and PvMSP10 proteins were measured by Luminex in a cohort of 422 Amazonian individuals with known history of Pv exposure (monthly data of infection status by qPCR and/or microscopy over five months). Both serological responses were able to discriminate between exposed and non-exposed individuals in a good manner, with slightly higher performance of anti-PvMSP10 IgGs (area under the curve AUC = 0.78 [95% CI = 0.72–0.83]) than anti-PvMSP8 IgGs (AUC = 0.72 [95% CI = 0.67–0.78]) (p = 0.01). In a second evaluation, the analysis by ELISA of 1251 plasma...
10
artículo
Background: Faced with the resurgence of malaria, malaria surveillance in the Peruvian Amazon incorporated consecutive active case detection (ACD) interventions using light microscopy (LM) as reactive measure in communities with an unusual high number of cases during high transmission season (HTS). We assessed the effectiveness in malaria detection of this local ACD-based strategy. Methods: A cohort study was conducted in June–July 2015 in Mazan, Loreto. Four consecutive ACD interventions at intervals of 10 days were conducted in four riverine communities (Gamitanacocha, Primero de Enero, Libertad and Urco Miraño). In each intervention, all inhabitants were visited at home, and finger-prick blood samples collected for immediate diagnosis by LM and on filter paper for later analysis by quantitative real-time polymerase chain reaction (qPCR). Effectiveness was calculated by dividing the...
11
artículo
Loop-mediated isothermal DNA amplification (LAMP) methodology offers an opportunity for point-of-care (POC) molecular detection of asymptomatic malaria infections. However, there is still little evidence on the feasibility of implementing this technique for population screenings in isolated field settings.
12
artículo
Background: Paediatric early warning systems (PEWS) aid in the early identification of clinical deterioration events in children admitted to hospital. We aimed to investigate the effect of PEWS implementation on mortality due to clinical deterioration in children with cancer in 32 resource-limited hospitals across Latin America. Methods: Proyecto Escala de Valoración de Alerta Temprana (Proyecto EVAT) is a quality improvement collaborative to implement PEWS in hospitals providing childhood cancer care. In this prospective, multicentre cohort study, centres joining Proyecto EVAT and completing PEWS implementation between April 1, 2017, and May 31, 2021, prospectively tracked clinical deterioration events and monthly inpatient-days in children admitted to hospital with cancer. De-identified registry data reported between April 17, 2017, and Nov 30, 2021, from all hospitals were included i...