Bordetella pertussis in children hospitalized with a respiratory infection: clinical characteristics and pathogen detection in household contacts

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Objective: Describe the prevalence of Bordetella pertussis via PCR in children under 5 years old hospitalized as probable cases of pertussis and report the most common clinical features among them. Results: A positive PCR result for B. pertussis was observed in 20.5% of our samples (18/88), one-thir...

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Detalles Bibliográficos
Autores: del Valle-Mendoza, Juana, Silva-Caso, Wilmer, Aguilar-Luis, Miguel Angel, del Valle-Vargas, Cristina, Cieza-Mora, Erico, Martins-Luna, Johanna, Aquino-Ortega, Ronald, Silva-Vásquez, Andrea, Bazán-Mayra, Jorge, Weilg, Pablo
Formato: artículo
Fecha de Publicación:2018
Institución:Universidad Peruana de Ciencias Aplicadas
Repositorio:UPC-Institucional
Lenguaje:inglés
OAI Identifier:oai:repositorioacademico.upc.edu.pe:10757/624653
Enlace del recurso:http://hdl.handle.net/10757/624653
Nivel de acceso:acceso abierto
Materia:Bordetella pertussis
PCR
Pertussis
Whooping cough
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dc.title.en_US.fl_str_mv Bordetella pertussis in children hospitalized with a respiratory infection: clinical characteristics and pathogen detection in household contacts
title Bordetella pertussis in children hospitalized with a respiratory infection: clinical characteristics and pathogen detection in household contacts
spellingShingle Bordetella pertussis in children hospitalized with a respiratory infection: clinical characteristics and pathogen detection in household contacts
del Valle-Mendoza, Juana
Bordetella pertussis
PCR
Pertussis
Whooping cough
title_short Bordetella pertussis in children hospitalized with a respiratory infection: clinical characteristics and pathogen detection in household contacts
title_full Bordetella pertussis in children hospitalized with a respiratory infection: clinical characteristics and pathogen detection in household contacts
title_fullStr Bordetella pertussis in children hospitalized with a respiratory infection: clinical characteristics and pathogen detection in household contacts
title_full_unstemmed Bordetella pertussis in children hospitalized with a respiratory infection: clinical characteristics and pathogen detection in household contacts
title_sort Bordetella pertussis in children hospitalized with a respiratory infection: clinical characteristics and pathogen detection in household contacts
author del Valle-Mendoza, Juana
author_facet del Valle-Mendoza, Juana
Silva-Caso, Wilmer
Aguilar-Luis, Miguel Angel
del Valle-Vargas, Cristina
Cieza-Mora, Erico
Martins-Luna, Johanna
Aquino-Ortega, Ronald
Silva-Vásquez, Andrea
Bazán-Mayra, Jorge
Weilg, Pablo
author_role author
author2 Silva-Caso, Wilmer
Aguilar-Luis, Miguel Angel
del Valle-Vargas, Cristina
Cieza-Mora, Erico
Martins-Luna, Johanna
Aquino-Ortega, Ronald
Silva-Vásquez, Andrea
Bazán-Mayra, Jorge
Weilg, Pablo
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.email.es_PE.fl_str_mv juana.delvalle@upc.pe
gian_will@hotmail.com
ma23aguilar@gmail.com
cristina.del.valle88@gmail.com
ericocieza@yahoo.es
johmarlu14@gmail.com
ronaldaquino.one@gmail.com
silvavasquezandrea@mail.com
jorgebazan7@gmail.com
pablo.weilg@gmail.com
dc.contributor.author.fl_str_mv del Valle-Mendoza, Juana
Silva-Caso, Wilmer
Aguilar-Luis, Miguel Angel
del Valle-Vargas, Cristina
Cieza-Mora, Erico
Martins-Luna, Johanna
Aquino-Ortega, Ronald
Silva-Vásquez, Andrea
Bazán-Mayra, Jorge
Weilg, Pablo
dc.subject.en_US.fl_str_mv Bordetella pertussis
PCR
Pertussis
Whooping cough
topic Bordetella pertussis
PCR
Pertussis
Whooping cough
description Objective: Describe the prevalence of Bordetella pertussis via PCR in children under 5 years old hospitalized as probable cases of pertussis and report the most common clinical features among them. Results: A positive PCR result for B. pertussis was observed in 20.5% of our samples (18/88), one-third of them were from infants between 2 and 3 months old. The most common symptoms were paroxysms of coughing (88.9%), difficulty breathing (72.2%), cyanosis (77.8%) and fever (50%). The mother was the most common symptomatic carrier (27.8%), followed by uncles/aunts (22.2%) among children with pertussis.
publishDate 2018
dc.date.accessioned.none.fl_str_mv 2018-11-27T04:05:52Z
dc.date.available.none.fl_str_mv 2018-11-27T04:05:52Z
dc.date.issued.fl_str_mv 2018-05
dc.type.en_US.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.issn.none.fl_str_mv 1756-0500
dc.identifier.doi.none.fl_str_mv 10.1186/s13104-018-3405-7
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/10757/624653
dc.identifier.journal.en_US.fl_str_mv BMC Research Notes
dc.identifier.isni.none.fl_str_mv 0000 0001 2196 144X
identifier_str_mv 1756-0500
10.1186/s13104-018-3405-7
BMC Research Notes
0000 0001 2196 144X
url http://hdl.handle.net/10757/624653
dc.language.iso.en_US.fl_str_mv eng
language eng
dc.relation.url.en_US.fl_str_mv https://bmcresnotes.biomedcentral.com/articles/10.1186/s13104-018-3405-7
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eu_rights_str_mv openAccess
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http://creativecommons.org/licenses/by-nc-sa/3.0/us/
dc.format.en_US.fl_str_mv application/pdf
dc.publisher.en_US.fl_str_mv BioMed Central Ltd.
dc.source.es_PE.fl_str_mv Universidad Peruana de Ciencias Aplicadas (UPC)
Repositorio Academico - UPC
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dc.source.journaltitle.none.fl_str_mv BMC Research Notes
dc.source.volume.none.fl_str_mv 11
dc.source.issue.none.fl_str_mv 1
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spelling del Valle-Mendoza, JuanaSilva-Caso, WilmerAguilar-Luis, Miguel Angeldel Valle-Vargas, CristinaCieza-Mora, EricoMartins-Luna, JohannaAquino-Ortega, RonaldSilva-Vásquez, AndreaBazán-Mayra, JorgeWeilg, Pablojuana.delvalle@upc.pegian_will@hotmail.comma23aguilar@gmail.comcristina.del.valle88@gmail.comericocieza@yahoo.esjohmarlu14@gmail.comronaldaquino.one@gmail.comsilvavasquezandrea@mail.comjorgebazan7@gmail.compablo.weilg@gmail.com2018-11-27T04:05:52Z2018-11-27T04:05:52Z2018-051756-050010.1186/s13104-018-3405-7http://hdl.handle.net/10757/624653BMC Research Notes0000 0001 2196 144XObjective: Describe the prevalence of Bordetella pertussis via PCR in children under 5 years old hospitalized as probable cases of pertussis and report the most common clinical features among them. Results: A positive PCR result for B. pertussis was observed in 20.5% of our samples (18/88), one-third of them were from infants between 2 and 3 months old. The most common symptoms were paroxysms of coughing (88.9%), difficulty breathing (72.2%), cyanosis (77.8%) and fever (50%). The mother was the most common symptomatic carrier (27.8%), followed by uncles/aunts (22.2%) among children with pertussis.This work was supported by fourth research incentive of the Universidad Peruana de Ciencias Aplicadas (UPC), Lima‑Peru.Revisión por paresapplication/pdfengBioMed Central Ltd.https://bmcresnotes.biomedcentral.com/articles/10.1186/s13104-018-3405-7info:eu-repo/semantics/openAccessAttribution-NonCommercial-ShareAlike 3.0 United Stateshttp://creativecommons.org/licenses/by-nc-sa/3.0/us/Universidad Peruana de Ciencias Aplicadas (UPC)Repositorio Academico - UPCBMC Research Notes111reponame:UPC-Institucionalinstname:Universidad Peruana de Ciencias Aplicadasinstacron:UPCBordetella pertussisPCRPertussisWhooping coughBordetella pertussis in children hospitalized with a respiratory infection: clinical characteristics and pathogen detection in household contactsinfo:eu-repo/semantics/article2018-11-27T04:05:53ZTHUMBNAIL10.1186s13104-018-3405-7.pdf.jpg10.1186s13104-018-3405-7.pdf.jpgGenerated Thumbnailimage/jpeg98292https://repositorioacademico.upc.edu.pe/bitstream/10757/624653/5/10.1186s13104-018-3405-7.pdf.jpgea5885daaf89da370c7cf8e5f1a78f8aMD55falseTEXT10.1186s13104-018-3405-7.pdf.txt10.1186s13104-018-3405-7.pdf.txtExtracted texttext/plain28715https://repositorioacademico.upc.edu.pe/bitstream/10757/624653/4/10.1186s13104-018-3405-7.pdf.txtc06d2fdf5a56140a26e087b0f8c84687MD54falseLICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://repositorioacademico.upc.edu.pe/bitstream/10757/624653/3/license.txt8a4605be74aa9ea9d79846c1fba20a33MD53falseCC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-81037https://repositorioacademico.upc.edu.pe/bitstream/10757/624653/2/license_rdf80294ba9ff4c5b4f07812ee200fbc42fMD52falseORIGINAL10.1186s13104-018-3405-7.pdf10.1186s13104-018-3405-7.pdfapplication/pdf1142928https://repositorioacademico.upc.edu.pe/bitstream/10757/624653/1/10.1186s13104-018-3405-7.pdf8c19665e42e5670feeed029db9aacbb9MD51true10757/624653oai:repositorioacademico.upc.edu.pe:10757/6246532019-08-30 08:19:38.285Repositorio académico upcupc@openrepository.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Bordetella pertussis in children hospitalized with a respiratory infection: clinical characteristics and pathogen detection in household contacts
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