Bordetella pertussis in children hospitalized with a respiratory infection: clinical characteristics and pathogen detection in household contacts

• Autores: del Valle-Mendoza, Juana, Silva-Caso, Wilmer, Aguilar-Luis, Miguel Angel, del Valle-Vargas, Cristina, Cieza-Mora, Erico, Martins-Luna, Johanna, Aquino-Ortega, Ronald, Silva-Vásquez, Andrea, Bazán-Mayra, Jorge, Weilg, Pablo
• Formato: artículo
• Fecha de Publicación: 2018
• Institución: Universidad Peruana de Ciencias Aplicadas
• Repositorio: UPC-Institucional
• Lenguaje: inglés
• OAI Identifier: oai:repositorioacademico.upc.edu.pe:10757/624653
• Enlace del recurso: http://hdl.handle.net/10757/624653
• Nivel de acceso: acceso abierto
• Materia: Bordetella pertussis; PCR; Pertussis; Whooping cough

Objective: Describe the prevalence of Bordetella pertussis via PCR in children under 5 years old hospitalized as probable cases of pertussis and report the most common clinical features among them. Results: A positive PCR result for B. pertussis was observed in 20.5% of our samples (18/88), one-third of them were from infants between 2 and 3 months old. The most common symptoms were paroxysms of coughing (88.9%), difficulty breathing (72.2%), cyanosis (77.8%) and fever (50%). The mother was the most common symptomatic carrier (27.8%), followed by uncles/aunts (22.2%) among children with pertussis.