Development of islets of Langerhans in pancreas of neonatal alpacas

• Autores: Rodríguez G., José, Espinoza B., Juan, Rojas Z., Gabriela, Lira M., Boris, Vásquez C., María, López-Torres, Bernardo, Caro M., César
• Formato: artículo
• Fecha de Publicación: 2015
• Institución: Universidad Nacional Mayor de San Marcos
• Repositorio: Revista UNMSM - Revista de Investigaciones Veterinarias del Perú
• Lenguaje: español
• OAI Identifier: oai:ojs.csi.unmsm:article/11171
• Enlace del recurso: https://revistasinvestigacion.unmsm.edu.pe/index.php/veterinaria/article/view/11171
• Nivel de acceso: acceso abierto
• Materia: endocrine pancreas; baby alpaca; neonatal development; páncreas endocrino; crías de alpaca; desarrollo neonatal

The aim of this study was to determine the postnatal development of Islets of Langerhans (IL) in alpacas of 0 to 45 days of age. The animals were divided in nine age groups with range of five days. The mumber of IL varied from 3.03 to 4.46 in 10x fields (with an ocular of 10x), the IL diameter varied from 67.89 to 72.55 μm, the number of β cells in the IL from 23.79 to 47.08 and other cells from 18.15 to 39.93. Moreover, the insulin receptor and the transport protein GLUT-2 were observed by immunohistochemistry on the first day of life. It is concluded that the number and size of IL increased with age (p<0.05) while β cells do not show the same trend.