El Linfoma de células grandes B difuso CD5 positivo es una entidad rara y agresiva. Pocos casos han sido descritos en Latinoamérica. Presentamos el caso que corresponde a un varón 69 años que desarrolla adenopatías cervicales, ilíacas e inguinales. La biopsia cervical demostró: Linfoma de células grandes B difuso CD5 positivo. El paciente recibió el régimen R-CHOP por 6 ciclos logrando respuesta completa. Siete meses después desarrolla recurrencia ganglionar recibiendo régimen R-ICE con intención de trasplante autólogo. El caso se describe por ser una entidad muy infrecuente y de gran agresividad.

CD5-positive diffuse large B-cell lymphoma is a rare and aggressive entity. Few cases have been described in Latin America. We present the case of a 69-year-old man who develops cervical, iliac, and inguinal lymphadenopathy. Cervical biopsy showed: CD5 positive diffuse large B cell lymphoma. The patient received the R-CHOP regimen for 6 cycles, achieving a complete response. Seven months later, he developed lymph node recurrence receiving the R-ICE regimen with the intention of autologous transplant. The case is described as being a very rare and highly aggressive entity.

Adult T-cell leukemia/lymphoma (ATLL) is an aggressive mature T-cell neoplasm caused by infection with the Human T-cell Lymphotropic Virus Type 1 (HTLV-1). Cardiac involvement in patients with ATLL is infrequent, and when it happens it is usually seen in aggressive ATLL subtypes. However, ATLL presenting as isolated cardiac valve involvement is extremely rare. To date, only three histologically proven cases of ATLL with isolated cardiac valve involvement have been reported. Herein, we describe a 61-year-old Peruvian man who presented heart failure symptoms secondary to progressive cardiac valve infiltration. The patient underwent mitral valve replacement with a mechanical prosthesis. Histopathological evaluation of the resected valve revealed leaflet thickening with a nodular appearance due to fibrous tissue containing atypical T-lymphocytes with Foxp3 expression, infiltrating all layers...

Introduction: Diffuse large B-cell lymphoma (DLBCL) is the most prevalent form of non-Hodgkin lymphoma in adults, with a high mortality rate. Low serum albumin can be a biological indicator of the disease reflected as increased inflammation or increased toxicities. Currently, the International Prognostic Index (IPI) is the accepted model for prognosis in patients with DLBCL. Objective: To determine the prognostic value of albumin in overall survival (OS) of patients with DLBCL treated with immunochemotherapy in a hospital in Peru during the period 2017-2019. Materials and methods: Analytical, cross-sectional, retrospective and observational study. It consisted of 161 patients with DLBCL diagnosed and treated during the mentioned period. The SPSS v27 program was used for statistical analysis. Hazard ratios (HR) and 95% confidence intervals (CI) were used to assess the prognostic impact of...