1
artículo
Publicado 2014
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Presenta la revisión de la literatura de todos los casos publicados de linfoma anaplásico de células grandes (ALCL por sus siglas en inglés) asociados a implantes mamarios desde 1997 hasta diciembre de 2012 y se estableció contacto con los autores correspondientes para actualizar el seguimiento clínico del ALCL.
2
artículo
Publicado 2019
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The first case of breast implant-associated anaplastic large cell lymphoma (breast implant ALCL) was described by John Keech and the late Brevator Creech in 1997. In the following 2 decades, much research has led to acceptance of breast implant ALCL as a specific clinicopathologic entity, a process that we bring up to life through the memories of 6 persons who were involved in this progress, although we acknowledge that many others also have contributed to the current state of the art of this disease. Dr. Keech recalls the events that led him and Creech to first report the disease. Ahmet Dogan and colleagues at the Mayo Clinic described a series of 4 patients with breast implant ALCL, and led to increased awareness of breast implant ALCL in the pathology community. Daphne de Jong and colleagues in the Netherlands were the first to provide epidemiologic evidence to support the association...
3
artículo
Publicado 2018
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El linfoma difuso de células B grandes (LDCBG) positivo al VEB, no especificado de otra manera (NOS) es un subtipo de linfoma agresivo poco común asociado con un peor pronóstico en los ancianos. Se ha informado DLBCL positivo para EBV en <5% de los pacientes occidentales sin inmunodeficiencia predisponente documentada. Existen muchos trastornos linfoproliferativos asociados con la infección por VEB, como granulomatosis linfomatoide, linfoma plasmablástico, LDCBG asociado con inflamación crónica, úlcera mucocutánea positiva para VEB, linfoma de derrame primario y linfoma de Hodgkin clásico. El LDCBG EBV-positivo, NOS es un diagnóstico de exclusión y se requiere una correlación clínico-patológica para diferenciar entre estos diagnósticos diferenciales. Los pacientes con enfermedad inflamatoria intestinal (EII) que reciben medicamentos inmunosupresores tienen un mayor riesgo...
4
artículo
Publicado 2018
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Disease overview Epstein Barr virus‐positive (EBV+) diffuse large B‐cell lymphoma (DLBCL), not otherwise specified (NOS) is an entity included in the 2016 WHO classification of lymphoid neoplasms. EBV+ DLBCL, NOS, is an aggressive B‐cell lymphoma associated with chronic EBV infection, and a poor prognosis with standard chemotherapeutic approaches. Diagnosis The diagnosis is made through a careful pathological evaluation. Detection of EBV‐encoded RNA is considered standard for diagnosis; however, a clear cutoff for positivity has not been defined. The differential diagnosis includes plasmablastic lymphoma, DLBCL associated with chronic inflammation, primary effusion lymphoma, HHV8+ DLBCL, NOS, and EBV+ mucocutaneuos ulcer. Risk‐stratification The International prognostic index (IPI) and the Oyama score can be used for risk‐stratification. The Oyama score includes age >70 years...
5
artículo
Publicado 2023
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Adult T-cell leukemia/lymphoma (ATLL) is an aggressive mature T-cell neoplasm caused by infection with the Human T-cell Lymphotropic Virus Type 1 (HTLV-1). Cardiac involvement in patients with ATLL is infrequent, and when it happens it is usually seen in aggressive ATLL subtypes. However, ATLL presenting as isolated cardiac valve involvement is extremely rare. To date, only three histologically proven cases of ATLL with isolated cardiac valve involvement have been reported. Herein, we describe a 61-year-old Peruvian man who presented heart failure symptoms secondary to progressive cardiac valve infiltration. The patient underwent mitral valve replacement with a mechanical prosthesis. Histopathological evaluation of the resected valve revealed leaflet thickening with a nodular appearance due to fibrous tissue containing atypical T-lymphocytes with Foxp3 expression, infiltrating all layers...
