Equisetum arvense (Equisetaceae) es una planta que posee efectos antiinflamatorios debido a suscompuestos fitoquímicos como los flavonoides, los cuales actúan a nivel de citocinas proinflamatorias,principalmente el TNF-α. Sin embargo, se conocen otras especies de Equisetum en el Perú, de lascuales no se ha demostrado dichos efectos. Una de estas especies es Equisetum bogotense, de la cualse extrajeron los flavonoides y fueron inoculados en Mus musculus BALB/c. Estos flavonoidesactuaron sobre los niveles de TNF-α producidos en la inflamación inducida experimentalmente enMus musculus BALB/c mediante la inoculación de carragenanos. Para la cuantificación de los nivelesde TNF-α se realizó la prueba de ELISA, obteniéndose que los flavonoides redujeron ligeramente losniveles de TNF-α, sin embargo, no hubo diferencia significativa entre las concentraciones utilizadas.

Equisetum arvense (Equisetaceae) es una planta que posee efectos antiinflamatorios debido a suscompuestos fitoquímicos como los flavonoides, los cuales actúan a nivel de citocinas proinflamatorias,principalmente el TNF-α. Sin embargo, se conocen otras especies de Equisetum en el Perú, de lascuales no se ha demostrado dichos efectos. Una de estas especies es Equisetum bogotense, de la cualse extrajeron los flavonoides y fueron inoculados en Mus musculus BALB/c. Estos flavonoidesactuaron sobre los niveles de TNF-α producidos en la inflamación inducida experimentalmente enMus musculus BALB/c mediante la inoculación de carragenanos. Para la cuantificación de los nivelesde TNF-α se realizó la prueba de ELISA, obteniéndose que los flavonoides redujeron ligeramente losniveles de TNF-α, sin embargo, no hubo diferencia significativa entre las concentraciones utilizadas.

Background: Ranitidine is a drug that is associated with mutagenesis by generating genetic alterations and / or cell carcinogenesis, but its genotoxicity in polychromatic erythrocytes is unknown. Therefore, the effect of ranitidine on DNA of micronucleated polychromatic erythrocytes (EPC) in albino rats (Rattus norvegicus, Holtzman strain) was researched by the micronucleus test. Materials and methods: Four groups of rats were studied: negative control with physiological saline solution (0.5 ml for 15 days); positive control with cyclophosphamide (dose 50 mg / kg for 2 days) and two experimental groups treated with ranitidine (doses 2 and 4 mg / kg for 15 days). The rats were euthanized and cytological preparations were obtained by 30 min staining in 5% giemsa. Results: An increase in the size and significant increase in the number of micronuclei in the EPC was found in the experimental ...

Microorganisms’ degradation of agro-industrial waste produces bad odors and greenhouse gases that contribute to global warming. Consequently, eco-friendly, sustainable biotechnological alternatives to this waste are sought to provide additional value, which is why this study’s objective was to develop a method of producing unicellular proteins from artichoke and asparagus agroindustrial waste using Rhodotorula mucilaginosa as a producer organism. Agricultural soil was collected from the Universidad Nacional de Trujillo (Peru), and R. mucilaginosa was isolated and identified using biochemical tests. Proteins and carotenoids were produced from artichokes and asparagus residues using the R. mucilaginosa yeast. Four substrate concentrations (10, 20, 30, and 40%) and a pH range (5–8.1) were used. They were incubated at 30 ◦C for 72 h. The results showed that protein and carotenoid yie...

Climate change represents one of the greatest challenges we face globally, and reducing carbon dioxide (CO2) emissions is among the most urgent actions. In this study, we explored an alternative approach using microalgae (Chlorella vulgaris) to capture CO2 from the air, employing an Arduino-controlled biofiltration system with accessible sensors such as the MQ-135 and TESTO 535. We tested different airflow rates (50, 75, and 100 L per hour) and nutrient combinations (N/P ratios of 0, 108.33, and 216.67) to identify the most efficient conditions. Unlike other studies, we integrated real-time monitoring of variables such as CO2 concentration, temperature, and light within a modular, easily adaptable system. The best results were achieved with a flow rate of 100 L/h and an N/P ratio of 216.67, yielding a capture efficiency of 34.88 % and a daily productivity of nearly to 1 g/L. This proposa...

Phenolic compounds have gained international interest due to their carcinogenic, toxic, and bioaccumulative properties, causing adverse effects in both animals and humans. As a result, there is a growing interest in finding alternative and eco-friendly treatment routes for phenol by exploring new microbial cultures with potential adaptation and biodegradation capabilities. In this study, the phenol removal efficiency of Yarrowia lipolytica YQ22 under laboratory conditions was determined. The YQ22 strain was obtained from diesel samples from a fuel station in Trujillo, Peru, isolated through serial dilutions on Sabouraud agar, and identified through its morphological characteristics using microscopy and molecular analysis by polymerase chain reaction of the ribosomal DNA internal transcribed spacer (ITS) and 5.8S regions. In the treatment, the effect of pH (5, 6 and 7) and temperature (25...