La enfermedad de Huntington (EH) es una enfermedad neurodegenerativa devastadora, hereditaria, caracterizada por  síntomas progresivos motores, cognitivos y psiquiátricos, los cuales aparecen mayormente durante la vida adulta. Su curso clínico produce   consecuencias físicas, emocionales, cognitivas, sociales y económicas graves en el paciente y cuidadores. Su prevalencia a nivel mundial se estima en 7-10 por 100000 habitantes pero, en la zona del Valle de Cañete en nuestro país, se estableció en más de 40 por 100,000. Actualmente no existe cura para la EH; sin embargo, se dan opciones terapéuticas para el alivio de  síntomas con el fin de mejorar la calidad de vida del paciente. Es en este rubro donde radica la importancia de los Cuidados Paliativos,  definidos por la Organización Mundial de la Salud como un enfoque de atención que, mediante medidas de prevención y al...

We present a patient with an opercular syndrome, with bilateral pseudobulbar symptoms and signs; most cases present involvement of both cerebral hemispheres, our patient had unilateral involvement. Clinical Case: A 65-year-old man, righthanded, with hypertension history, referred to a disease period of one year and one month of evolution, characterized by sudden monoparesis in the right upper limb, facial asymmetry, anarthria with bilateral pseudobulbar involvement. Magnetic resonance imaging showed ischemic lesion of the left opercular area. Discussion: The opercular or biopercular syndrome, also known as Foix-Chavany-Marie syndrome, is a rare entity characterized by involvement of the bilateral cerebral opercular area, which compromises the cortico-bulbar/protuberancial pathway. An important feature is the presence of the automatic-voluntary motor dissociation and the most frequent eti...

Wallenberg syndrome is the most common ischemic stroke of the posterior circulation, caused by an atherothrombotic obstruction of the vertebral or the postero-inferior cerebellar artery. This occlusion leads to ischemia in the lateral portion of the bulb, which results in the representative triad of Horner’s syndrome, ataxia on the ipsilateral side of the lesion and sensory alterations. There is a greater risk of suffering from this condition with anatomical variations such as a hypoplastic and/or duplicated vertebral artery. The case of a 45-year-old woman admitted as an emergency due to hypoesthesia on the right side of the face and on the left side of the body, as well as dysphagia and vomiting is reported. MRI studies revealed an ischemic lesion in the right-side of the bulbar area; in the angio-MRI a hypoplastic right vertebral artery was evidenced whereas the angio-TC showed a hy...

Acute retroviral syndrome (SRA) is one of the possible clinical scenarios in the early stages of HIV infection, with varying presentations, characterized by high viral copies and nonspecific symptoms. We describe the case of a 21-year-old man who presented with acute onset encephalopathy and cerebellar ataxia which led to the diagnosis of HIV, in whom the diagnosis of SRA was established.