The objective of the present experiment was to test the oxytocin effect on embryonic survival during the luteolysis risk period in post-mating alpacas. Forty-three adult alpacas that were receptive to the male and bearing an ovarian follicle >7 mm of diameter were selected. They were mated with fertile males and the copula lasted for >10 minutes. Ovulation was secured with con 1 ml of GnRH i.m. (Day 0). Within the group of alpacas with a corpus luteum confirmed by trans-rectal echography on day 7, 30 were randomly selected and assigned into two similar groups. One group received 40 IU oxitocin on days 9, 10 and 11 post-mating days distributed in 4 doses of 10 IU every 5 hours. The second group was considered as control. The embryonic survival was evaluated based on sexual receptivity on days 8, 10, 11, 12 and 40 post-mating and confirmed on day 40 by ultrasonography. The oxytocin t...

El objetivo del presente experimento fue comprobar el efecto de la oxitocina en la supervivencia embrionaria durante el periodo de riesgo por luteolisis en alpacas posservicio. Se seleccionaron 43 alpacas adultas receptivas al macho y con un folículo ovárico e»7 mm de diámetro, que fueron sometidas a monta controlada e»10 minutos con macho fértil, asegurando la ovulación con 1 ml de GnRH i.m. (Día 0). Dentro de las alpacas con cuerpo lúteo confirmado por ecografía transrectal en el día 7, se seleccionaron 30 animales al azar y se distribuyeron en dos grupos similares. Al primer grupo se le aplicó 40 UI/d de oxitocina los días 9, 10 y 11 pos-servicio, fraccionadas en 4 dosis de 10 UI cada 5 horas. Al segundo grupo se le aplicó un placebo como control. Se evaluó la supervivencia embrionaria por receptividad sexual los días 8, 10, 11, 12 y 40 pos-servicio. La viabilidad embr...

Background: Abandonment of treatment is a major cause of treatment failure and poor survival in children with cancer in low- and middle-income countries. The incidence of treatment abandonment in Peru has not been reported. The aim of this study was to examine the prevalence of and factors associated with treatment abandonment by pediatric patients with solid tumors in Peru. Methods: We retrospectively reviewed the sociodemographic and clinical data of children referred between January 2012 and December 2014 to the two main tertiary centers for childhood cancer in Peru. The definition of treatment abandonment followed the International Society of Paediatric Oncology, Paediatric Oncology in Developing Countries, Abandonment of Treatment recommendation. Results: Data from 1135 children diagnosed with malignant solid tumors were analyzed, of which 209 (18.4%) abandoned treatment. Bivariate ...