This article presents a general vision of the history of the university of San Marcos and exposes the institutional mechanisms across which it was granting academic degrees to the graduating students in fulfillment of a set of educational intentions raised between 1860 and 1928. The aim of the text is to reconstruct the role that fulfills the university in the society in a historical conjuncture and to revise the negative image left by the generations of Nine hundred and of the Centenary. Finally, it postulates a few brief reflections on the value of the graduation theses as historical documents and the use of contemporary historiography.

This article presents a general vision of the history of the university of San Marcos and exposes the institutional mechanisms across which it was granting academic degrees to the graduating students in fulfillment of a set of educational intentions raised between 1860 and 1928. The aim of the text is to reconstruct the role that fulfills the university in the society in a historical conjuncture and to revise the negative image left by the generations of Nine hundred and of the Centenary. Finally, it postulates a few brief reflections on the value of the graduation theses as historical documents and the use of contemporary historiography.

El presente trabajo tiene como objetivo ampliar el conocimiento del uso de las cimbras metálicas en el sostenimiento en minería subterránea, mediante el control y registro de las mediciones de convergencia, lo que nos permitirá mejorar nuestra metodología de diseño inicial y tomar medidas de control apropiadas en el tiempo oportuno a un costo óptimo cuando se tengan problemas de altos esfuerzos o deterioro de cimbras por influencia de factores hidrogeológicos adversos. La información recolectada (teórica - campo) y analizada nos permite conocer: diseños teóricos para sostenimiento con cimbras (arcos de acero) y elegir aquel que más se ajuste a nuestra realidad, el comportamiento de las cimbras frente a las presiones de la excavación (principalmente laterales). Y determinar: el tiempo de vida según el tipo de cimbras y condición hidrogeológica presente (varía de seco a f...

This master thesis is devoted to the design, analysis, and experimental validation of an energy-based control strategy for the well-known benchmark cart-pole system in implicit Port-Hamiltonian (PH) representation. The control scheme performs two tasks: swingup and (local) stabilization. The swing-up controller is carried out on the basis of a generalized energy function and consists of bringing the pendulum trajectories from the lower (stable) position to a limit cycle (homoclinic orbit), which passes by the upright (unstable) position, as well as the cart trajectories to the desired point. The (local) stabilizing controller is designed under a novel algebraic Interconnection and Damping Assignment Passivity-Based Control (IDA-PBC) technique and ensures the upright (asymptotic) stabilization of the pendulum as well as the cart at a desired position. To illustrate the effectiveness of th...

This master thesis is devoted to the design, analysis, and experimental validation of an energy-based control strategy for the well-known benchmark cart-pole system in implicit Port-Hamiltonian (PH) representation. The control scheme performs two tasks: swingup and (local) stabilization. The swing-up controller is carried out on the basis of a generalized energy function and consists of bringing the pendulum trajectories from the lower (stable) position to a limit cycle (homoclinic orbit), which passes by the upright (unstable) position, as well as the cart trajectories to the desired point. The (local) stabilizing controller is designed under a novel algebraic Interconnection and Damping Assignment Passivity-Based Control (IDA-PBC) technique and ensures the upright (asymptotic) stabilization of the pendulum as well as the cart at a desired position. To illustrate the effectiveness of th...

Esta tesis se ha desarrollado en la Escuela Profesional de Ingeniería Civil de la Facultad de Ingeniería Civil y Arquitectura de la Universidad Nacional de San Martín - Tara poto, con fines de titulación como Ingeniero Civil. El proyecto de tesis está enfocado para dar a conocer una solución rápida, económica y óptima para el mejoramiento vial, ya que en muchas vías, el descuido en el drenaje o la ausencia de ésta, hace que las mismas se deterioren y presenten agrietamientos, fisuras, etc. Causando malestar para los usuarios, falta de comunicación entre pueblos y ciudades, o en el peor de los casos el cambio total de la carpeta de rodadura. Este proyecto Estudio definitivo del camino vecinal Nueva Unión Alto la Huarpia (4+715 km) distrito de Alonso de Alvarado – Lamas – San Martin, se realizó con la finalidad de participar en la solución de la problemática vial que ex...

Background: Previous studies have shown oxidative stress in pemphigus vulgaris and pemphigus foliaceus, nevertheless, it remains unknown whether a similar response is characteristic of endemic pemphigus foliaceus in Peru. Objectives: To determine the oxidative stress response in endemic pemphigus foliaceus patients and subjects with positive for anti-desmoglein1 antibodies (anti-dsg1) from endemic areas of Peru. Subjects and Methods: This is a cross-sectional study. The study population included 21 patients with Endemic Pemphigus foliaceus and 12 healthy subjects with anti-dsg1 antibodies from the Peruvian Amazon (Ucayali), as well as 30 healthy control subjects. Malondialdehyde, an indicator of lipid peroxidation by free radicals, was measured in serum. Results: We collected 21 cases of endemic pemphigus foliaceus, 15 of them with active chronic disease and 6 in clinical remission. Seru...

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El Pénfigo Foliáceo Endémico (PFE) es una enfermedad autoinmune de la piel endémica en áreas de la Amazonía. Se revisa el caso de una mujer de 36 años que presentó PFE en la semana 17 de embarazo. A las 29 semanas, comenzó un tratamiento antimicrobiano y esteroides. En el momento del parto la enfermedad en la madre ya había sido controlada con corticoterapia, mostrando inmunofluorescencia indirecta (IFI) para IgG total negativa. De esta manera no habría descarga de anticuerpos hacia la placenta, y la recién nacida también mostró títulos negativos. Durante el seguimiento la niña varió sus títulos de anticuerpos, de negativo a 1/20. Recientemente se demostró que 45% de familiares de pacientes con PFE presentan anticuerpos anti Dsg-1, siendo más frecuente en familiares de primer grado.

Introduction: endemic pemphigus foliaceus (PFE) has been described at the beginning of the 50s in the peruvian forest. In 2006,Ortega & col. reported the presence of desmoglein 1 antibodies in Pueblo Libre, Ucayali. Nevertheless, immune reports does not exist on patients’ relatives with PFE in the zone.Objetives: to compare the immunopathologic profiles of healthy subjects from Pueblo Libre (an area in Ucayali, endemic for pemphigus foliaceus), with healthy relatives of patients with endemic pemphigus foliaceus (EPF) and healthy controls from non-endemic areas.Materials and methods: this is a prospective multicentric study performed from June to August 2006. The sample consisted of 41 healthy subjects from the Pueblo Libre community, 11 relatives of EPF patients and 20 healthy subjects from non-endemic areas. Blood samples were obtained for immunopathologic studies (E...

Introduction: endemic pemphigus foliaceus (PFE) has been described at the beginning of the 50s in the peruvian forest. In 2006,Ortega & col. reported the presence of desmoglein 1 antibodies in Pueblo Libre, Ucayali. Nevertheless, immune reports does not exist on patients’ relatives with PFE in the zone.Objetives: to compare the immunopathologic profiles of healthy subjects from Pueblo Libre (an area in Ucayali, endemic for pemphigus foliaceus), with healthy relatives of patients with endemic pemphigus foliaceus (EPF) and healthy controls from non-endemic areas.Materials and methods: this is a prospective multicentric study performed from June to August 2006. The sample consisted of 41 healthy subjects from the Pueblo Libre community, 11 relatives of EPF patients and 20 healthy subjects from non-endemic areas. Blood samples were obtained for immunopathologic studies (E...

Objectives: To determine the effectiveness of Peruvian purple corn (Zea mays) administration in serum lipids levels reduction (hypolipidemic effect) in non hypertensive diabetic patients with dyslipidemia; to compare hypolipidemic effect of Peruvian purple corn and simvastatin. Design: Clinical essay. Setting: Instituto de Investigaciones Clinicas, Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima, Peru. Participants: Non hypertensive dyslipidemic diabetic patients. Interventions: Between January and October 2006 two groups of 15 non hypertensive dyslipidemic diabetic patients were randomly formed, patients with recent diagnosis, without previous treatment and without chronic complications; one group recieved simvastatin 40 mg/day and the other group Peruvian purple corn (dehydrated and micropulverized pills 1g/day) for 30 days. Patients had low fat diet with weekly nu...