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artículo

Photoelectrocatalytic degradation of 2,4-dichlorophenol in a TiO2 nanotube-coated disc flow reactor

Publicado por
Montenegro-Ayo R., Morales-Gomero J.C., Alarcon H., Corzo A., Westerhoff P., Garcia-Segura S.

Publicado 2021

Photoelectrocatalytic (PEC) water treatment is a promising technology for organic pollution abatement. Much of the prior research focused on material discovery and optimization. However, challenges exist in scaling-up PEC processes and are associated with designing reactors with effective light irradiation on electrode surfaces and, simultaneously, efficient electrode configurations. We design and demonstrate key reactor design principles, which influence reaction mechanisms, for a reactor using a TiO2 nanotube-coated disc flow reactor. Degradation of organochlorinated 2,4-dichlorophenol was studied as representative carcinogenic micropollutant. The synergistic photoelectrocatalytic process showed 5-fold faster degradation kinetics than solely electrocatalytic treatment or a greater than 2-fold enhancement over photocatalysis alone. Applicability of photoelectrocatalytic treatment was de...

artículo

Patients Age 40 Years and Younger with Multiple Myeloma Have the Same Prognosis as Older Patients: An Analysis of Real-World Patients' Evidence from Latin America

Publicado por
Martinez-Cordero, H, Peña, C, Schutz, NP, Bove, V, Villano, F, Beltran, C, Donoso, J, Lopez-Vidal, H, Roa-Salinas, MA, Soto, P, Ochoa, P, Duarte, P, Remaggi, G, Corzo, A, Shanley, C, Lopresti, S, Orlando, S, Verri, V, Quiroga, LD, Fantl, D, Ramirez, J, Ospina-Idarraga, A, Idrobo, H, Quintero, G, Gomez, R, Cantu-Martinez, O, Gomez-Almaguer, D, Ruiz-Arguelles, GJ, Galvez-Cardenas, KM, Salazar, LA, Novoa-Caicedo, I, Fuentes-Lacouture, MC, Spirko, P, Arbelaez, MI, Pereira, M, Valdes, J, Vasquez, J, Von-Glasenapp, A, Riva, E

Publicado 2023

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PURPOSEMultiple myeloma (MM) is a highly heterogeneous, incurable disease most frequently diagnosed in the elderly. Therefore, data on clinical characteristics and outcomes in the very young population are scarce.PATIENTS AND METHODSWe analyzed clinical characteristics, response to treatment, and survival in 103 patients with newly diagnosed MM age 40 years or younger compared with 256 patients age 41-50 years and 957 patients age 51 years or older.RESULTSThere were no statistical differences in sex, isotype, International Scoring System, renal involvement, hypercalcemia, anemia, dialysis, bony lesions, extramedullary disease, and lactate dehydrogenase (LDH). The most used regimen in young patients was cyclophosphamide, bortezomib, dexamethasone, followed by cyclophosphamide, thalidomide, dexamethasone and bortezomib, thalidomide, dexamethasone. Of the patients age 40 years or younger, o...