Seasonal predictions have a great socioeconomic potential if they are reliable and skillful. In this study, we assess the prediction performance of SEAS5, version 5 of the seasonal prediction system of the European Centre for Medium-Range Weather Forecasts (ECMWF), over South America against homogenized station data. For temperature, we find the highest prediction performances in the tropics during austral summer, where the probability that the predictions correctly discriminate different observed outcomes is 70%. In regions lying to the east of the Andes, the predictions of maximum and minimum temperature still exhibit considerable performance, while farther to the south in Chile and Argentina the temperature prediction performance is low. Generally, the prediction performance of minimum temperature is slightly lower than for maximum temperature. The prediction performance of precipitat...