High prevalence of Bordetella pertussis in severe acute respiratory infections in hospitalized children under 5 years in Lima, Peru

Descripción del Articulo

ASTMH 64th Annual Meeting. October 25-29, 2015 Philadelphia Marriott Downtown Philadelphia, Pennsylvania USA
Detalles Bibliográficos
Autores: Pavic Espinoza, Ivana, Bendezu Medina, Sandy, Herrera Alzamora, Angella, Pons, Maria J, Hernández, Adrian V., Del Valle Mendoza, Juana Mercedes, Universidad Peruana de Ciencias Aplicadas (UPC)
Formato: objeto de conferencia
Fecha de Publicación:2015
Institución:Universidad Peruana de Ciencias Aplicadas
Repositorio:UPC-Institucional
Lenguaje:inglés
OAI Identifier:oai:repositorioacademico.upc.edu.pe:10757/582376
Enlace del recurso:http://hdl.handle.net/10757/582376
Nivel de acceso:acceso abierto
Materia:Bordetella pertussis
Peru
id UUPC_a3c3fe8a0f9d48309dbd1a241379eda9
oai_identifier_str oai:repositorioacademico.upc.edu.pe:10757/582376
network_acronym_str UUPC
network_name_str UPC-Institucional
repository_id_str 2670
dc.title.es_PE.fl_str_mv High prevalence of Bordetella pertussis in severe acute respiratory infections in hospitalized children under 5 years in Lima, Peru
title High prevalence of Bordetella pertussis in severe acute respiratory infections in hospitalized children under 5 years in Lima, Peru
spellingShingle High prevalence of Bordetella pertussis in severe acute respiratory infections in hospitalized children under 5 years in Lima, Peru
Pavic Espinoza, Ivana
Bordetella pertussis
Peru
title_short High prevalence of Bordetella pertussis in severe acute respiratory infections in hospitalized children under 5 years in Lima, Peru
title_full High prevalence of Bordetella pertussis in severe acute respiratory infections in hospitalized children under 5 years in Lima, Peru
title_fullStr High prevalence of Bordetella pertussis in severe acute respiratory infections in hospitalized children under 5 years in Lima, Peru
title_full_unstemmed High prevalence of Bordetella pertussis in severe acute respiratory infections in hospitalized children under 5 years in Lima, Peru
title_sort High prevalence of Bordetella pertussis in severe acute respiratory infections in hospitalized children under 5 years in Lima, Peru
dc.creator.es_PE.fl_str_mv Universidad Peruana de Ciencias Aplicadas (UPC)
author Pavic Espinoza, Ivana
author_facet Pavic Espinoza, Ivana
Bendezu Medina, Sandy
Herrera Alzamora, Angella
Pons, Maria J
Hernández, Adrian V.
Del Valle Mendoza, Juana Mercedes
Universidad Peruana de Ciencias Aplicadas (UPC)
author_role author
author2 Bendezu Medina, Sandy
Herrera Alzamora, Angella
Pons, Maria J
Hernández, Adrian V.
Del Valle Mendoza, Juana Mercedes
Universidad Peruana de Ciencias Aplicadas (UPC)
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Pavic Espinoza, Ivana
Bendezu Medina, Sandy
Herrera Alzamora, Angella
Pons, Maria J
Hernández, Adrian V.
Del Valle Mendoza, Juana Mercedes
dc.subject.es_PE.fl_str_mv Bordetella pertussis
Peru
topic Bordetella pertussis
Peru
description ASTMH 64th Annual Meeting. October 25-29, 2015 Philadelphia Marriott Downtown Philadelphia, Pennsylvania USA
publishDate 2015
dc.date.accessioned.es_PE.fl_str_mv 2015-11-18T21:10:57Z
dc.date.available.es_PE.fl_str_mv 2015-11-18T21:10:57Z
dc.date.issued.fl_str_mv 2015-11-18
dc.type.es_PE.fl_str_mv info:eu-repo/semantics/conferenceObject
format conferenceObject
dc.identifier.uri.es_PE.fl_str_mv http://hdl.handle.net/10757/582376
url http://hdl.handle.net/10757/582376
dc.language.iso.es_PE.fl_str_mv eng
language eng
dc.rights.es_PE.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.es_PE.fl_str_mv application/pdf
dc.publisher.es_PE.fl_str_mv Universidad Peruana de Ciencias Aplicadas (UPC)
dc.source.es_PE.fl_str_mv Universidad Peruana de Ciencias Aplicadas (UPC)
Repositorio Académico - UPC
dc.source.none.fl_str_mv reponame:UPC-Institucional
instname:Universidad Peruana de Ciencias Aplicadas
instacron:UPC
instname_str Universidad Peruana de Ciencias Aplicadas
instacron_str UPC
institution UPC
reponame_str UPC-Institucional
collection UPC-Institucional
bitstream.url.fl_str_mv https://repositorioacademico.upc.edu.pe/bitstream/10757/582376/1/P1766-%20Pons%20Casellas%2c%20M.J..ppt
https://repositorioacademico.upc.edu.pe/bitstream/10757/582376/2/P1766-%20Pons%20Casellas%2c%20M.J..pdf
https://repositorioacademico.upc.edu.pe/bitstream/10757/582376/3/license_url
https://repositorioacademico.upc.edu.pe/bitstream/10757/582376/4/license_text
https://repositorioacademico.upc.edu.pe/bitstream/10757/582376/5/license_rdf
https://repositorioacademico.upc.edu.pe/bitstream/10757/582376/6/license.txt
https://repositorioacademico.upc.edu.pe/bitstream/10757/582376/7/P1766-%20Pons%20Casellas%2c%20M.J..ppt.txt
https://repositorioacademico.upc.edu.pe/bitstream/10757/582376/9/P1766-%20Pons%20Casellas%2c%20M.J..pdf.txt
https://repositorioacademico.upc.edu.pe/bitstream/10757/582376/8/P1766-%20Pons%20Casellas%2c%20M.J..ppt.jpg
https://repositorioacademico.upc.edu.pe/bitstream/10757/582376/10/P1766-%20Pons%20Casellas%2c%20M.J..pdf.jpg
bitstream.checksum.fl_str_mv ea30a206349391acd4ec1644276e635f
d773fe87938409bfb9089a3239da5faa
4afdbb8c545fd630ea7db775da747b2f
ae2fe251842ade1134c5d9bb99b6eefe
9da0b6dfac957114c6a7714714b86306
1ed8f33c5404431ad7aabc05080746c5
c33559e25f9526cf31e8cd6c2d526a55
23c95a79549e1f743a3b59837d39c068
a878424a60b5af9592c9d2793aa9ef1e
117209c29daab143b2a8b212be6a4612
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
MD5
MD5
MD5
MD5
MD5
MD5
MD5
repository.name.fl_str_mv Repositorio académico upc
repository.mail.fl_str_mv upc@openrepository.com
_version_ 1837187585475084288
spelling Pavic Espinoza, IvanaBendezu Medina, SandyHerrera Alzamora, AngellaPons, Maria JHernández, Adrian V.Del Valle Mendoza, Juana MercedesUniversidad Peruana de Ciencias Aplicadas (UPC)2015-11-18T21:10:57Z2015-11-18T21:10:57Z2015-11-18http://hdl.handle.net/10757/582376ASTMH 64th Annual Meeting. October 25-29, 2015 Philadelphia Marriott Downtown Philadelphia, Pennsylvania USAAcute respiratory infections (ARI) are the main cause of morbidity and mortality in children under 5 years worldwide. Bordetella pertussis is a highly contagious bacterium that can cause serious illness, and approximately half of infected infants less than 1 year old are hospitalized. Also, pertussis immunization series is not completed until six months of age, leaving young infants vulnerable to pertussis. In Peru, pertussis is an increasing health problem despite immunization efforts, and the role of B. pertussis in ARI is unknown. We determined the prevalence of B. pertussis among children under 5 years old admitted to Hospital Nacional Cayetano Heredia in Lima with diagnosis of ARI between Jan-2009 and Dec 2010. Epidemiological and clinical features were collected, and presence of B. pertussis was determined by PCR (pertussis toxin and IS481 gene). A total of 596 nasopharyngeal samples among children under 5 years were analyzed. In 114 (19.1%) samples were positive for B. pertussis. 32.5% of sample positive to B. pertussis were diagnosed as viral pneumonia at diagnosis. Importantly, 71.9% of cases were under 12 months of age and 58.8% have been contact with other ARI infected people. Significant differences in clinical symptoms between the total ARI cases and B. pertussis cases were not found. The most frequent symptoms in B. pertussis cases were fever (100%), rhinorrhea 78%, cough 71.9% and respiratory distress 60.5%. One child died due to the infection. B. pertussis cases showed a seasonal distribution with peaks during the months March June and November. This study shows the high prevalence of B. pertussis in infants who were hospitalized due to severe acute respiratory infections in Lima, Peru. Epidemiologic surveillance programs for B. pertussis are essential in the future in Peruapplication/pdfengUniversidad Peruana de Ciencias Aplicadas (UPC)info:eu-repo/semantics/openAccessUniversidad Peruana de Ciencias Aplicadas (UPC)Repositorio Académico - UPCreponame:UPC-Institucionalinstname:Universidad Peruana de Ciencias Aplicadasinstacron:UPCBordetella pertussis1cff9bed-cd36-4fec-98e7-05966131f053600Perud6e19394-1ad0-4de6-8bb9-5ec7e2e6d476600High prevalence of Bordetella pertussis in severe acute respiratory infections in hospitalized children under 5 years in Lima, Peruinfo:eu-repo/semantics/conferenceObject2018-06-16T01:01:42ZAcute respiratory infections (ARI) are the main cause of morbidity and mortality in children under 5 years worldwide. Bordetella pertussis is a highly contagious bacterium that can cause serious illness, and approximately half of infected infants less than 1 year old are hospitalized. Also, pertussis immunization series is not completed until six months of age, leaving young infants vulnerable to pertussis. In Peru, pertussis is an increasing health problem despite immunization efforts, and the role of B. pertussis in ARI is unknown. We determined the prevalence of B. pertussis among children under 5 years old admitted to Hospital Nacional Cayetano Heredia in Lima with diagnosis of ARI between Jan-2009 and Dec 2010. Epidemiological and clinical features were collected, and presence of B. pertussis was determined by PCR (pertussis toxin and IS481 gene). A total of 596 nasopharyngeal samples among children under 5 years were analyzed. In 114 (19.1%) samples were positive for B. pertussis. 32.5% of sample positive to B. pertussis were diagnosed as viral pneumonia at diagnosis. Importantly, 71.9% of cases were under 12 months of age and 58.8% have been contact with other ARI infected people. Significant differences in clinical symptoms between the total ARI cases and B. pertussis cases were not found. The most frequent symptoms in B. pertussis cases were fever (100%), rhinorrhea 78%, cough 71.9% and respiratory distress 60.5%. One child died due to the infection. B. pertussis cases showed a seasonal distribution with peaks during the months March June and November. This study shows the high prevalence of B. pertussis in infants who were hospitalized due to severe acute respiratory infections in Lima, Peru. Epidemiologic surveillance programs for B. pertussis are essential in the future in PeruORIGINALP1766- Pons Casellas, M.J..pptP1766- Pons Casellas, M.J..pptapplication/vnd.ms-powerpoint2589696https://repositorioacademico.upc.edu.pe/bitstream/10757/582376/1/P1766-%20Pons%20Casellas%2c%20M.J..pptea30a206349391acd4ec1644276e635fMD51trueP1766- Pons Casellas, M.J..pdfP1766- Pons Casellas, M.J..pdfapplication/pdf485468https://repositorioacademico.upc.edu.pe/bitstream/10757/582376/2/P1766-%20Pons%20Casellas%2c%20M.J..pdfd773fe87938409bfb9089a3239da5faaMD52falseCC-LICENSElicense_urllicense_urltext/plain; charset=utf-849https://repositorioacademico.upc.edu.pe/bitstream/10757/582376/3/license_url4afdbb8c545fd630ea7db775da747b2fMD53falselicense_textlicense_texttext/html; charset=utf-821468https://repositorioacademico.upc.edu.pe/bitstream/10757/582376/4/license_textae2fe251842ade1134c5d9bb99b6eefeMD54falselicense_rdflicense_rdfapplication/rdf+xml; charset=utf-823148https://repositorioacademico.upc.edu.pe/bitstream/10757/582376/5/license_rdf9da0b6dfac957114c6a7714714b86306MD55falseLICENSElicense.txtlicense.txttext/plain; charset=utf-81659https://repositorioacademico.upc.edu.pe/bitstream/10757/582376/6/license.txt1ed8f33c5404431ad7aabc05080746c5MD56falseTEXTP1766- Pons Casellas, M.J..ppt.txtP1766- Pons Casellas, M.J..ppt.txtExtracted texttext/plain9538https://repositorioacademico.upc.edu.pe/bitstream/10757/582376/7/P1766-%20Pons%20Casellas%2c%20M.J..ppt.txtc33559e25f9526cf31e8cd6c2d526a55MD57falseP1766- Pons Casellas, M.J..pdf.txtP1766- Pons Casellas, M.J..pdf.txtExtracted Texttext/plain10386https://repositorioacademico.upc.edu.pe/bitstream/10757/582376/9/P1766-%20Pons%20Casellas%2c%20M.J..pdf.txt23c95a79549e1f743a3b59837d39c068MD59falseTHUMBNAILP1766- Pons Casellas, M.J..ppt.jpgP1766- Pons Casellas, M.J..ppt.jpgGenerated Thumbnailimage/jpeg9435https://repositorioacademico.upc.edu.pe/bitstream/10757/582376/8/P1766-%20Pons%20Casellas%2c%20M.J..ppt.jpga878424a60b5af9592c9d2793aa9ef1eMD58falseP1766- Pons Casellas, M.J..pdf.jpgP1766- Pons Casellas, M.J..pdf.jpgGenerated Thumbnailimage/jpeg149712https://repositorioacademico.upc.edu.pe/bitstream/10757/582376/10/P1766-%20Pons%20Casellas%2c%20M.J..pdf.jpg117209c29daab143b2a8b212be6a4612MD510falseCONVERTED2_211854310757/582376oai:repositorioacademico.upc.edu.pe:10757/5823762019-08-30 07:46:19.4Repositorio académico upcupc@openrepository.comTk9OLUVYQ0xVU0lWRSBESVNUUklCVVRJT04gTElDRU5TRQoKQnkgc2lnbmluZyBhbmQgc3VibWl0dGluZyB0aGlzIGxpY2Vuc2UsIHlvdSAodGhlIGF1dGhvcihzKSBvciBjb3B5cmlnaHQKb3duZXIpIGdyYW50cyB0byB0aGUgPE1ZIElOU1RBTkNFIE5BTUU+ICg8SUQ+KSB0aGUgbm9uLWV4Y2x1c2l2ZSByaWdodCB0byByZXByb2R1Y2UsCnRyYW5zbGF0ZSAoYXMgZGVmaW5lZCBiZWxvdyksIGFuZC9vciBkaXN0cmlidXRlIHlvdXIgc3VibWlzc2lvbiAoaW5jbHVkaW5nCnRoZSBhYnN0cmFjdCkgd29ybGR3aWRlIGluIHByaW50IGFuZCBlbGVjdHJvbmljIGZvcm1hdCBhbmQgaW4gYW55IG1lZGl1bSwKaW5jbHVkaW5nIGJ1dCBub3QgbGltaXRlZCB0byBhdWRpbyBvciB2aWRlby4KCllvdSBhZ3JlZSB0aGF0IDxJRD4gbWF5LCB3aXRob3V0IGNoYW5naW5nIHRoZSBjb250ZW50LCB0cmFuc2xhdGUgdGhlCnN1Ym1pc3Npb24gdG8gYW55IG1lZGl1bSBvciBmb3JtYXQgZm9yIHRoZSBwdXJwb3NlIG9mIHByZXNlcnZhdGlvbi4KCllvdSBhbHNvIGFncmVlIHRoYXQgPElEPiBtYXkga2VlcCBtb3JlIHRoYW4gb25lIGNvcHkgb2YgdGhpcyBzdWJtaXNzaW9uIGZvcgpwdXJwb3NlcyBvZiBzZWN1cml0eSwgYmFjay11cCBhbmQgcHJlc2VydmF0aW9uLgoKWW91IHJlcHJlc2VudCB0aGF0IHRoZSBzdWJtaXNzaW9uIGlzIHlvdXIgb3JpZ2luYWwgd29yaywgYW5kIHRoYXQgeW91IGhhdmUKdGhlIHJpZ2h0IHRvIGdyYW50IHRoZSByaWdodHMgY29udGFpbmVkIGluIHRoaXMgbGljZW5zZS4gWW91IGFsc28gcmVwcmVzZW50CnRoYXQgeW91ciBzdWJtaXNzaW9uIGRvZXMgbm90LCB0byB0aGUgYmVzdCBvZiB5b3VyIGtub3dsZWRnZSwgaW5mcmluZ2UgdXBvbgphbnlvbmUncyBjb3B5cmlnaHQuCgpJZiB0aGUgc3VibWlzc2lvbiBjb250YWlucyBtYXRlcmlhbCBmb3Igd2hpY2ggeW91IGRvIG5vdCBob2xkIGNvcHlyaWdodCwKeW91IHJlcHJlc2VudCB0aGF0IHlvdSBoYXZlIG9idGFpbmVkIHRoZSB1bnJlc3RyaWN0ZWQgcGVybWlzc2lvbiBvZiB0aGUKY29weXJpZ2h0IG93bmVyIHRvIGdyYW50IDxJRD4gdGhlIHJpZ2h0cyByZXF1aXJlZCBieSB0aGlzIGxpY2Vuc2UsIGFuZCB0aGF0CnN1Y2ggdGhpcmQtcGFydHkgb3duZWQgbWF0ZXJpYWwgaXMgY2xlYXJseSBpZGVudGlmaWVkIGFuZCBhY2tub3dsZWRnZWQKd2l0aGluIHRoZSB0ZXh0IG9yIGNvbnRlbnQgb2YgdGhlIHN1Ym1pc3Npb24uCgpJRiBUSEUgU1VCTUlTU0lPTiBJUyBCQVNFRCBVUE9OIFdPUksgVEhBVCBIQVMgQkVFTiBTUE9OU09SRUQgT1IgU1VQUE9SVEVECkJZIEFOIEFHRU5DWSBPUiBPUkdBTklaQVRJT04gT1RIRVIgVEhBTiA8SUQ+LCBZT1UgUkVQUkVTRU5UIFRIQVQgWU9VIEhBVkUKRlVMRklMTEVEIEFOWSBSSUdIVCBPRiBSRVZJRVcgT1IgT1RIRVIgT0JMSUdBVElPTlMgUkVRVUlSRUQgQlkgU1VDSApDT05UUkFDVCBPUiBBR1JFRU1FTlQuCgo8SUQ+IHdpbGwgY2xlYXJseSBpZGVudGlmeSB5b3VyIG5hbWUocykgYXMgdGhlIGF1dGhvcihzKSBvciBvd25lcihzKSBvZiB0aGUKc3VibWlzc2lvbiwgYW5kIHdpbGwgbm90IG1ha2UgYW55IGFsdGVyYXRpb24sIG90aGVyIHRoYW4gYXMgYWxsb3dlZCBieSB0aGlzCmxpY2Vuc2UsIHRvIHlvdXIgc3VibWlzc2lvbi4K
score 13.958958
High prevalence of Bordetella pertussis in severe acute respiratory infections in hospitalized children under 5 years in Lima, Peru
Nota importante:
La información contenida en este registro es de entera responsabilidad de la institución que gestiona el repositorio institucional donde esta contenido este documento o set de datos. El CONCYTEC no se hace responsable por los contenidos (publicaciones y/o datos) accesibles a través del Repositorio Nacional Digital de Ciencia, Tecnología e Innovación de Acceso Abierto (ALICIA).

Ejemplares Similares