Background: Pertussis diagnosis may go unrecognized when other pathogens, such as respiratory syncytial virus (RSV) circulate. Methods: A prospective cross-sectional study was conducted in Lima, Peru from January 2009 to September 2010. A total of 596 children under 5 years old admitted with clinical diagnoses of acute respiratory infections were test for B. pertussis and RSV detection by polymerase chain reaction (PCR). Results: The pertussis toxin and IS481 genes were detected in 19.12% (114/596) of the cases and the respiratory syncytial viruses (RSV-A and RSV-B) were identified in 17.28% (103/596) of patients. Infants under 3 months old were the most frequently affected by this pathogens in 43% (49/114) and 35.9% (37/103) respectively. An increase of B. pertussis was observed from February to March and from October to November with a Seasonal index between 1.32-1.51 and 1.24-3.5 resp...

El síndrome de Turcot es un desorden genético caracterizado por la asociación de tumores primarios neuroepiteliales del sistema nervioso central y poliposis adenomatosa del colon. Se describen dos variedades. En el tipo I los tumores suelen ser glioblastomas y se asocian a un síndrome de Lynch o cáncer colorectal hereditario no polipósico. En el tipo II predominan los meduloblastomas y se asocian a poliposis múltiple familiar, ya sea la forma clásica o atenuada. El presente caso debutó a los 7 años de edad con un meduloblastoma que logró ser curado, pero 20 años después desarrolla un meningioma cerebral recidivante. A los 36 años presenta anemia por sangrado digestivo y se descubre a la colonoscopía una poliposis adenomatosa del colon, con displasia de alto grado. Hasta donde conocemos es el primer caso de síndrome de Turcot que se reporta en nuestro país.

ASTMH 64th Annual Meeting. October 25-29, 2015 Philadelphia Marriott Downtown Philadelphia, Pennsylvania USA