Phenolic composition, antioxidant and anti-proliferative activities of edible and medicinal plants from the Peruvian Amazon

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Among 23 extracts of medicinal and edible plants tested, Mauritia flexuosa L.f., Arecaceae, showed significant antioxidant ability (DPPH and ORAC = 1062.9 and 645.9 ± 51.4 μg TE/mg extract, respectively), while Annona montana Macfad., Annonaceae, demonstrated the most promising anti-proliferative ef...

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Detalles Bibliográficos
Autores: Tauchen, Jan, Bortl, Ludvik, Huml, Lukas, Miksatkova, Petra, Doskocil, Ivo, Marsik, Petr, Panduro Villegas, Pablo Pedro, Bendezu Flores, Ymber, Van Damme, Patrick, Lojka, Bohdan, Havlik, Jaroslav, Lapcik, Oldrich, Kokoska, Ladislav
Formato: artículo
Fecha de Publicación:2016
Institución:Instituto Nacional de Innovación Agraria
Repositorio:INIA-Institucional
Lenguaje:inglés
OAI Identifier:oai:null:20.500.12955/1143
Enlace del recurso:https://repositorio.inia.gob.pe/handle/20.500.12955/1143
http://dx.doi.org/10.1016/j.bjp.2016.03.016
Nivel de acceso:acceso abierto
Materia:Antioxidant
Anticarcinogenic
Phenolic compounds
Plant extracts
Biotecnología agrícola, Biotecnología alimentaria
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dc.title.es_PE.fl_str_mv Phenolic composition, antioxidant and anti-proliferative activities of edible and medicinal plants from the Peruvian Amazon
title Phenolic composition, antioxidant and anti-proliferative activities of edible and medicinal plants from the Peruvian Amazon
spellingShingle Phenolic composition, antioxidant and anti-proliferative activities of edible and medicinal plants from the Peruvian Amazon
Tauchen, Jan
Antioxidant
Anticarcinogenic
Phenolic compounds
Plant extracts
Biotecnología agrícola, Biotecnología alimentaria
title_short Phenolic composition, antioxidant and anti-proliferative activities of edible and medicinal plants from the Peruvian Amazon
title_full Phenolic composition, antioxidant and anti-proliferative activities of edible and medicinal plants from the Peruvian Amazon
title_fullStr Phenolic composition, antioxidant and anti-proliferative activities of edible and medicinal plants from the Peruvian Amazon
title_full_unstemmed Phenolic composition, antioxidant and anti-proliferative activities of edible and medicinal plants from the Peruvian Amazon
title_sort Phenolic composition, antioxidant and anti-proliferative activities of edible and medicinal plants from the Peruvian Amazon
author Tauchen, Jan
author_facet Tauchen, Jan
Bortl, Ludvik
Huml, Lukas
Miksatkova, Petra
Doskocil, Ivo
Marsik, Petr
Panduro Villegas, Pablo Pedro
Bendezu Flores, Ymber
Van Damme, Patrick
Lojka, Bohdan
Havlik, Jaroslav
Lapcik, Oldrich
Kokoska, Ladislav
author_role author
author2 Bortl, Ludvik
Huml, Lukas
Miksatkova, Petra
Doskocil, Ivo
Marsik, Petr
Panduro Villegas, Pablo Pedro
Bendezu Flores, Ymber
Van Damme, Patrick
Lojka, Bohdan
Havlik, Jaroslav
Lapcik, Oldrich
Kokoska, Ladislav
author2_role author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Tauchen, Jan
Bortl, Ludvik
Huml, Lukas
Miksatkova, Petra
Doskocil, Ivo
Marsik, Petr
Panduro Villegas, Pablo Pedro
Bendezu Flores, Ymber
Van Damme, Patrick
Lojka, Bohdan
Havlik, Jaroslav
Lapcik, Oldrich
Kokoska, Ladislav
dc.subject.es_PE.fl_str_mv Antioxidant
Anticarcinogenic
Phenolic compounds
Plant extracts
topic Antioxidant
Anticarcinogenic
Phenolic compounds
Plant extracts
Biotecnología agrícola, Biotecnología alimentaria
dc.subject.ocde.es_PE.fl_str_mv Biotecnología agrícola, Biotecnología alimentaria
description Among 23 extracts of medicinal and edible plants tested, Mauritia flexuosa L.f., Arecaceae, showed significant antioxidant ability (DPPH and ORAC = 1062.9 and 645.9 ± 51.4 μg TE/mg extract, respectively), while Annona montana Macfad., Annonaceae, demonstrated the most promising anti-proliferative effect (IC50 for Hep-G2 and HT-29 = 2.7 and 9.0 μg/ml, respectively). However, combinatory antioxidant/anti-proliferative effect was only detected in Oenocarpus bataua Mart., Arecaceae (DPPH = 903.8 and ORAC = 1024 μg TE/mg extract; IC50 for Hep-G2 and HT-29 at 102.6 and 38.8 μg/ml, respectively) and Inga edulis Mart., Fabaceae (DPPH = 337.0 and ORAC = 795.7 μg TE/mg extract; IC50 for Hep-G2 and HT-29 at 36.3 and 57.9 μg/ml, respectively). Phenolic content was positively correlated with antioxidant potential, however not with anti-proliferative effect. None of these extracts possessed toxicity towards normal foetal lung cells, suggesting their possible use in development of novel plant-based agents with preventive and/or therapeutic action against oxidative stress-related diseases.
publishDate 2016
dc.date.accessioned.none.fl_str_mv 2020-10-03T01:22:17Z
dc.date.available.none.fl_str_mv 2020-10-03T01:22:17Z
dc.date.issued.fl_str_mv 2016-06-14
dc.type.es_PE.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.citation.es_PE.fl_str_mv Tauchen, J.; Bortl, L.; Huml, L.; Miksatkova, P.; Doskocil, I.; Marsik, P.; Panduro, P.; Bendezu, Y.; Van Damme, P.; Lojka, B.; Havlik, J.; Lapcik, O.; Kokoska, L. (2016). Phenolic composition, antioxidant and anti-proliferative activities of edible and medicinal plants from the Peruvian Amazon. Revista Brasileira de Farmacognosia Volume 26, Issue 6, Pages 728-737. doi: 10.1016/j.bjp.2016.03.016
dc.identifier.uri.none.fl_str_mv https://repositorio.inia.gob.pe/handle/20.500.12955/1143
dc.identifier.journal.es_PE.fl_str_mv Revista Brasileira de Farmacognosia
dc.identifier.doi.none.fl_str_mv http://dx.doi.org/10.1016/j.bjp.2016.03.016
identifier_str_mv Tauchen, J.; Bortl, L.; Huml, L.; Miksatkova, P.; Doskocil, I.; Marsik, P.; Panduro, P.; Bendezu, Y.; Van Damme, P.; Lojka, B.; Havlik, J.; Lapcik, O.; Kokoska, L. (2016). Phenolic composition, antioxidant and anti-proliferative activities of edible and medicinal plants from the Peruvian Amazon. Revista Brasileira de Farmacognosia Volume 26, Issue 6, Pages 728-737. doi: 10.1016/j.bjp.2016.03.016
Revista Brasileira de Farmacognosia
url https://repositorio.inia.gob.pe/handle/20.500.12955/1143
http://dx.doi.org/10.1016/j.bjp.2016.03.016
dc.language.iso.es_PE.fl_str_mv eng
language eng
dc.relation.ispartof.es_PE.fl_str_mv Revista Brasileira de Farmacognosia Volume 26, Issue 6, November–December 2016, Pages 728-737
dc.relation.publisherversion.es_PE.fl_str_mv http://dx.doi.org/10.1016/j.bjp.2016.03.016
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dc.coverage.spatial.es_PE.fl_str_mv Perú
dc.publisher.es_PE.fl_str_mv El Sevier
dc.publisher.country.es_PE.fl_str_mv Brasil
dc.source.es_PE.fl_str_mv Instituto Nacional de Innovación Agraria
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spelling Tauchen, JanBortl, LudvikHuml, LukasMiksatkova, PetraDoskocil, IvoMarsik, PetrPanduro Villegas, Pablo PedroBendezu Flores, YmberVan Damme, PatrickLojka, BohdanHavlik, JaroslavLapcik, OldrichKokoska, LadislavPerú2020-10-03T01:22:17Z2020-10-03T01:22:17Z2016-06-14Tauchen, J.; Bortl, L.; Huml, L.; Miksatkova, P.; Doskocil, I.; Marsik, P.; Panduro, P.; Bendezu, Y.; Van Damme, P.; Lojka, B.; Havlik, J.; Lapcik, O.; Kokoska, L. (2016). Phenolic composition, antioxidant and anti-proliferative activities of edible and medicinal plants from the Peruvian Amazon. Revista Brasileira de Farmacognosia Volume 26, Issue 6, Pages 728-737. doi: 10.1016/j.bjp.2016.03.016https://repositorio.inia.gob.pe/handle/20.500.12955/1143Revista Brasileira de Farmacognosiahttp://dx.doi.org/10.1016/j.bjp.2016.03.016Among 23 extracts of medicinal and edible plants tested, Mauritia flexuosa L.f., Arecaceae, showed significant antioxidant ability (DPPH and ORAC = 1062.9 and 645.9 ± 51.4 μg TE/mg extract, respectively), while Annona montana Macfad., Annonaceae, demonstrated the most promising anti-proliferative effect (IC50 for Hep-G2 and HT-29 = 2.7 and 9.0 μg/ml, respectively). However, combinatory antioxidant/anti-proliferative effect was only detected in Oenocarpus bataua Mart., Arecaceae (DPPH = 903.8 and ORAC = 1024 μg TE/mg extract; IC50 for Hep-G2 and HT-29 at 102.6 and 38.8 μg/ml, respectively) and Inga edulis Mart., Fabaceae (DPPH = 337.0 and ORAC = 795.7 μg TE/mg extract; IC50 for Hep-G2 and HT-29 at 36.3 and 57.9 μg/ml, respectively). Phenolic content was positively correlated with antioxidant potential, however not with anti-proliferative effect. None of these extracts possessed toxicity towards normal foetal lung cells, suggesting their possible use in development of novel plant-based agents with preventive and/or therapeutic action against oxidative stress-related diseases.Introduction. Materials and methods. Results. Discussion. Conclusion. 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Phenolic composition, antioxidant and anti-proliferative activities of edible and medicinal plants from the Peruvian Amazon
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