1
artículo
Publicado 2017
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Compound usnic acid (1), isolated from lichen Evernia prunastri (Cajamarca-Peru) and the synthesis and characterization of its acyl-hydrazone (2), from the condensation reaction between usnic acid and isoniazid in an ethanol solution under reflux, giving an overall yield of 95%, were evaluated. Both compounds were evaluated and compared with isoniazid according to its anti-Mycobacterium tuberculosis activity based on the tetrazolium microplate assay (TEMA). Compound 1 had MIC (minimal inhibitory concentration) value of 16.0 μg/mL in each test of H37Rv (susceptible type), TB DM 97 (resistant wild type) and MDR DM 1098 (multi drug resistances type) strains. In similar tests, compound 2 MIC values were 2.0, 64.0 and 64.0 μg/mL respectively.
2
artículo
Publicado 2014
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In this research was to evaluated the antioxidant and photoprotective capacity of a lotion and a gel made with stabilized extract of the fruits of camu camu (Myrciaria dubia Kunth). Quality controls physicochemical, microbiological and stability to normal and accelerated conditions were performed, which allowed to develop initial parameters sunscreens extract of camu camu. Antioxidant activity by DPPH and ABTS method, values of 876.729 umol Trolox/g camu camu for gel and 1389.650 umol Trolox/g camu camu for lotion was determined (DPPH method) and values of 15.330 mmol Trolox/g camu camu for gel and 23.384 mmol Trolox/g