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artículo
Publicado 2017
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Compound usnic acid (1), isolated from lichen Evernia prunastri (Cajamarca-Peru) and the synthesis and characterization of its acyl-hydrazone (2), from the condensation reaction between usnic acid and isoniazid in an ethanol solution under reflux, giving an overall yield of 95%, were evaluated. Both compounds were evaluated and compared with isoniazid according to its anti-Mycobacterium tuberculosis activity based on the tetrazolium microplate assay (TEMA). Compound 1 had MIC (minimal inhibitory concentration) value of 16.0 μg/mL in each test of H37Rv (susceptible type), TB DM 97 (resistant wild type) and MDR DM 1098 (multi drug resistances type) strains. In similar tests, compound 2 MIC values were 2.0, 64.0 and 64.0 μg/mL respectively.
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artículo
Publicado 2016
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Activated carbons were prepared from corncob and red mombin seed and impregnated with chitosan. Field Emission Scanning Microscopy (FESEM) micrographs confirm the presence of chitosan in the activated carbon surface. Adsorptive and antibacterial properties of the prepared materials were compared with two adsorbents used in commercial water filters. Equilibrium adsorption experiments showed that the materials prepared in this study had maximum adsorption capacity to methylene blue that is comparable with those of the commercial adsorbents (between 145 and 192 mg/g). Activated carbons impregnated with chitosan exhibited higher antibacterial capacity against E. coli than the commercial adsorbents. The activated carbons prepared from corncob reach levels of reduction as higher as 96,3%. Meanwhile the commercial activated carbons had reduction values lower than 60,3%.