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1
artículo
Of the 17.326 patients with cervical cancer registered in the INEN between 1952 and 1979, 403 were 76 years or older at diagnosis (2.3%). The average age in this group was 80.6 years and older was 99 years. The first sex was at 19 and the average latency period 61 years, in contrast to 16 and seven years for the group of 123 patients under 25 years. The distribution showed predominance of clinical stay in the añosas advanced disease, although the parametrial involvement (comparison between stays A and B) was significantly lower (p <0.001) than in young, possibly due to anatomical changes involution. Squamous cell carcinoma was the predominant type and significantly more frequent (98%) in those over 76, with lower incidence of adenocarcinoma and mucoepidermoid carcinoma. The linioplasmocitario cervical stromal infiltrate was more frequent in younger patients, in which an inverse relation...
2
artículo
Of the 17.326 patients with cervical cancer registered in the INEN between 1952 and 1979, 403 were 76 years or older at diagnosis (2.3%). The average age in this group was 80.6 years and older was 99 years. The first sex was at 19 and the average latency period 61 years, in contrast to 16 and seven years for the group of 123 patients under 25 years. The distribution showed predominance of clinical stay in the añosas advanced disease, although the parametrial involvement (comparison between stays A and B) was significantly lower (p <0.001) than in young, possibly due to anatomical changes involution. Squamous cell carcinoma was the predominant type and significantly more frequent (98%) in those over 76, with lower incidence of adenocarcinoma and mucoepidermoid carcinoma. The linioplasmocitario cervical stromal infiltrate was more frequent in younger patients, in which an inverse relat...
3
artículo
Of the 17.326 patients with cervical cancer registered in the INEN between 1952 and 1979, 403 were 76 years or older at diagnosis (2.3%). The average age in this group was 80.6 years and older was 99 years. The first sex was at 19 and the average latency period 61 years, in contrast to 16 and seven years for the group of 123 patients under 25 years. The distribution showed predominance of clinical stay in the añosas advanced disease, although the parametrial involvement (comparison between stays A and B) was significantly lower (p <0.001) than in young, possibly due to anatomical changes involution. Squamous cell carcinoma was the predominant type and significantly more frequent (98%) in those over 76, with lower incidence of adenocarcinoma and mucoepidermoid carcinoma. The linioplasmocitario cervical stromal infiltrate was more frequent in younger patients, in which an inverse relat...
4
tesis de grado
El Síndrome de Burnout hace referencia a personas que viven en estado continuo de fatiga, frustración, estrés, generando desgaste e incapacidad laboral y social, carencia de humanización, disminución de energía, motivación y realización personal. El Burnout disminuye la capacidad para afrontar el estrés laboral, genera consecuencias en el trabajador y la empresa, con síntomas emocionales como ansiedad, hostilidad, depresión, aparición de alteraciones del comportamiento como hábitos tóxicos, ausentismo laboral y secuelas en la salud física como insomnio, trastornos gastrointestinales, dolores de cabeza, etc. La investigación, de método descriptivo, buscó identificar el nivel de Burnout y sus dimensiones (agotamiento emocional, despersonalización y poca realización personal) en trabajadores del área de riesgos de una entidad bancaria en La Molina, con una población de...
5
artículo
PURPOSEThis study aims to describe genomic characteristics of patients with metastatic prostate cancer (mPC).PATIENTS AND METHODSThis study is a retrospective, multicenter cohort study of patients with mPC and reports on genomic testing. Patients were included from 12 academic centers in five countries.RESULTSA total of 349 patients with PC were included in this study. Most patients (209, 59.9%) were de novo metastatic. Genomic analysis was performed in 233 (66.6%) patients in the metastatic castration-resistant prostate cancer (mCRPC) setting, and only 115 (32.8%) patients had a tumor evaluation in the metastatic hormone sensitive prostate cancer scenario. The evaluation of somatic and/or germline mutations was performed through multigene panel analyses in 290 (83.09%) patients, and next-generation sequencing of BRCA1 and BRCA2 genes was performed in 59 (16.91%) patients. Analyzing the ...
6
revisión
Bone sarcoma are infrequent diseases, representing < 0.2% of all adult neoplasms. A multidisciplinary management within reference centers for sarcoma, with discussion of the diagnostic and therapeutic strategies within an expert multidisciplinary tumour board, is essential for these patients, given its heterogeneity and low frequency. This approach leads to an improvement in patient's outcome, as demonstrated in several studies. The Sarcoma European Latin-American Network (SELNET), aims to improve clinical outcome in sarcoma care, with a special focus in Latin-American countries. These Clinical Practice Guidelines (CPG) have been developed and agreed by a multidisciplinary expert group (including medical and radiation oncologist, surgical oncologist, orthopaedic surgeons, radiologist, pathologist, molecular biologist and representatives of patients advocacy groups) of the SELNET ...
7
artículo
Bone sarcoma are infrequent diseases, representing < 0.2% of all adult neoplasms. A multidisciplinary management within reference centers for sarcoma, with discussion of the diagnostic and therapeutic strategies within an expert multidisciplinary tumour board, is essential for these patients, given its heterogeneity and low frequency. This approach leads to an improvement in patient's outcome, as demonstrated in several studies. The Sarcoma European Latin-American Network (SELNET), aims to improve clinical outcome in sarcoma care, with a special focus in Latin-American countries. These Clinical Practice Guidelines (CPG) have been developed and agreed by a multidisciplinary expert group (including medical and radiation oncologist, surgical oncologist, orthopaedic surgeons, radiologist, pathologist, molecular biologist and representatives of patients advocacy groups) of the SELNET ...
8
artículo
Soft tissue sarcoma (STS) and gastrointestinal tumors (GIST) encompass > 80 different histologic subtypes. Clinical practice guidelines for STS and GIST still lack in Latin-American countries. Tailored clinical guidelines are instrumental to improve outcome in sarcoma patients in LatinAmerican countries. This is the first review establishing STS and GIST guidelines for the purpose of LatinAmerican clinical practices to our knowledge.
9
revisión
Soft tissue sarcoma (STS) is a heterogeneous group of neoplasms, encompassing > 80 different histologic subtypes. Approximately three quarter of sarcoma arise from soft-tissue, about 15% are gastrointestinal stromal tumours (GISTs) and bone sarcoma represent the remaining 10%. The current guidelines will focus on soft-tissue and GIST, excluding Kaposi sarcoma and non-pleomorphic rhabdomyosarcoma. Bone sarcomas are covered in a different paper.