La enfermedad diarreica aguda es la causa más común de muerte en niños menores de 5 años, esta enfermedad es provocada por bacterias, virus o parásitos. La diarrea básicamente es síntoma de una infección del tracto digestivo. Esta enfermedad se da como consecuencia de una higiene inadecuada, el virus, bacterias y/o parásitos causantes de las infecciones diarreicas también puede propagarse de una persona a otra a través de alimentos elaborados o almacenados en condiciones antihigiénicas o agua potable contaminada. Para lograr reducir el riesgo a esta enfermedad, existen medidas, tales como tener acceso al agua potable con un saneamiento excelente, lavarse las manos con jabón y lavar los alimentos de manera adecuada. La investigación tiene como objetivo general, determinar la relación entre medidas preventivas y factores de riesgo en pacientes pediátricos con enfermedad dia...

Background: Genetic testing for hereditary cancers is inconsistently applied within the healthcare systems in Latin America. In Peru, the prevalence and spectrum of cancer-predisposing germline variants is thus poorly characterized. Purpose: To determine the spectrum and prevalence of cancer-predisposing germline variants and variants of uncertain significance (VUS) in high-risk individuals located in a Peruvian low-resource setting city. Methods: Individuals presenting clinical criteria for hereditary cancer syndromes or being unaffected with familial history of cancer were included in the study. Samples from a total of 84 individuals were subjected to a high-throughput DNA sequencing assay that targeted a panel of 94 cancer predisposition genes. The pathogenicity of detected germline variants was classified according to the established American College of Medical Genetics and Genomics ...

Background: Genetic testing for hereditary cancers is inconsistently applied within the healthcare systems in Latin America. In Peru, the prevalence and spectrum of cancer-predisposing germline variants is thus poorly characterized. Purpose: To determine the spectrum and prevalence of cancer-predisposing germline variants and variants of uncertain significance (VUS) in high-risk individuals located in a Peruvian low-resource setting city. Methods: Individuals presenting clinical criteria for hereditary cancer syndromes or being unaffected with familial history of cancer were included in the study. Samples from a total of 84 individuals were subjected to a high-throughput DNA sequencing assay that targeted a panel of 94 cancer predisposition genes. The pathogenicity of detected germline variants was classified according to the established American College of Medical Genetics and Genomics ...