El objetivo de esta investigación fue determinar el efecto hipoglicemiante de la administración oral del extracto hidroalcohólico de las hojas y flores de Otholobium pubescens (Poiret) Grimes, en la hiperglicemia experimental inducida por aloxano en ratas albinas. Se demostró que la administración de 500 mg/kg p.c, durante 33 días de tratamiento, redujo significativamente los niveles de glicemia de 390 a 223 mg/dl.

Objective: Determine the result of the comparison of the Lethal Dose 50 (LD50) of ethanolic extracts of 5 plants from the coast and mountains of Peru. Material and Methods: Basic design study The study will be inductive, experimental, transversal and prospective. The study will be experimental, because there will be influence of the researcher on the variables under study, on the other hand it will be a cross-sectional study, since it indicates that the data collection will be carried out in a single period of time and prospective since the data will be collected after the approach of the study. Results: By carrying out the tests between the different concentrations of the extracts and when they were subjected to the nauplii, it has been determined that the medicinal species from the coast are more toxic than the medicinal species from the mountains, this is due more than anything to two...

Objective: This study evaluated the sedative effect of the hydroalcoholic extracts from the leaves of Valeriana pinnatifida Ruiz & Pav (valerian) and Passiflora edulis Sims (passionflower) in albino mice (Holtzman). Material and Methods: 30 Holtzman albino mice were used, acquired from the National Agrarian University La Molina (UNALM). The mice were selected and assigned to groups using simple random probability sampling, forming 6 groups of 5 specimens each. Each group received a different treatment with the hydroalcoholic extracts: Valeriana pinnatifida at doses of 20 mg/kg and 50 mg/kg, and Passiflora edulis at doses of 50 mg/kg and 100 mg/kg. To induce anxiety, the elevated plus maze test was used. Subsequently, ANOVA and Tukey tests were applied to determine the concentration and group with the highest sedative activity. Results: The results indicate that the hydroalcoholic ext...