Objective: To select native microorganisms with the ability to degrade non-steroidal anti-inflammatory drugs (Naproxen, Paracetamol, Ibuprofen and Diclofenac) and psychotropic drugs (Carbamazepine, Alprazolam and Clonazepam) from wastewater. Material and Methods: This study examines the degradation of microorganisms in wastewater against anti-inflammatory and psychotropic drugs in Lima. Samples were collected, diluted and plated. After colony verification, degradation capacity was assessed by measuring turbidity and absorbance at 600 nm in a spectrophotometer. Results: Bacterial colonies were analyzed, highlighting characteristics such as white color, circular shape, entire edge, smooth texture, medium size and predominance of gram-positive bacteria. Anti-inflammatory and psychotropic drugs were evaluated, and specific responses of microorganisms were observed. Turbidity in the tubes ind...

Objective: This study evaluated the sedative effect of the hydroalcoholic extracts from the leaves of Valeriana pinnatifida Ruiz & Pav (valerian) and Passiflora edulis Sims (passionflower) in albino mice (Holtzman). Material and Methods: 30 Holtzman albino mice were used, acquired from the National Agrarian University La Molina (UNALM). The mice were selected and assigned to groups using simple random probability sampling, forming 6 groups of 5 specimens each. Each group received a different treatment with the hydroalcoholic extracts: Valeriana pinnatifida at doses of 20 mg/kg and 50 mg/kg, and Passiflora edulis at doses of 50 mg/kg and 100 mg/kg. To induce anxiety, the elevated plus maze test was used. Subsequently, ANOVA and Tukey tests were applied to determine the concentration and group with the highest sedative activity. Results: The results indicate that the hydroalcoholic ext...

Objective: This study aimed to evaluate the antagonistic effect of native microorganisms from agricultural soils against phytopathogenic fungi associated with representative crops in the region.  Material and Methods: Bacteria and fungi were isolated from soil samples collected from various agricultural crops using conventional microbiological methods. Subsequently, in vitro direct confrontation tests were performed to determine the antagonistic activity of the isolated microorganisms. Results: None of the evaluated bacteria showed antagonistic activity against the phytopathogenic fungi in tomato, pepper, carrot, orange, and ulluco crops. In contrast, some fungi, particularly H-pap-11 and H-pap-15, showed significant inhibition of the phytopathogens in tomato, pepper, and carrot, highlighting their potential as biocontrol agents. Conclusions: Although no antagonistic activity was de...

Objective: The objective of this study was to demonstrate whether a gel formulation developed with collagen extracted from fish scales is stable, functional, and safe for cosmetic applications. Material and Methods: A gel formulation derived from fish scales was developed, and physicochemical parameters (pH, viscosity, protein, lipid, carbohydrate, ash, and moisture content) were analyzed following AOAC (Association of Official Analytical Chemists) methods. Additionally, microbiological aspects (mesophilic bacteria, coliforms, molds, yeasts, and Salmonella spp.) were evaluated, and a sensory test was conducted with consumers. Results: The results showed a pH of 6.8 and a viscosity of 150 cP, which are suitable for stability. Protein content was 25%, carbohydrates reached 60.2%, and lipids were 5.5%. No Salmonella spp. was detected, and other microbiological parameters remained within per...

Objective: To evaluate the antimicrobial effect of plant extracts from native species of Moyobamba against clinically relevant pathogenic microorganisms. Material and Methods: Samples from five plant species were collected, and extracts were obtained through maceration with solvents of different polarities. A phytochemical analysis was performed to identify secondary metabolites, and antimicrobial activity was assessed using well diffusion and broth microdilution methods against Escherichia coli, Pseudomonas aeruginosa, Salmonella enterica, Staphylococcus aureus, and Klebsiella pneumoniae. Results: Only the bark extract of Indano (Byrsonima crassifolia) exhibited antimicrobial activity, inhibiting exclusively S. aureus with a minimum inhibitory concentration (MIC) of 0.195 mg/mL. Conclusions: The bark of B. crassifolia contains compounds with antibacterial potential against S. aureus, su...

Objectives: Determine if training to prevent parasitosis in Peruvian school children was effective. Human beings face various diseases caused by different pathogenic agents, one of them is parasitosis, which often go unnoticed in Latin American countries. The prevalence of parasitosis is high, affecting individuals, families and communities. The lack of sanitation and cultural practices contribute to its spread, with the most vulnerable populations being those in poverty, immunosuppressed people, older adults and children. In Peru, the lack of education has increased the prevalence of these infections, which highlights the need to develop educational interventions, through awareness workshops, for their prevention, especially in school populations to raise awareness about the risks of the disease and the importance of hygiene and prevention of parasitosis. Material and Methods: 10 primar...