1
artículo
Publicado 2020
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The case of a 5-year-old crossbred female cat in her first gestation was presented for consultation. The cat had a stillborn present in the birth canal, which was extracted manually. A second puppy is expelled alive but was euthanized because of her clinical infeasibility. The two puppies presented a malformation in the abdominal region with exposure of some viscera, considered as Schistosomus reflexus syndrome. The radiological and necropsy diagnostic evaluation of the second puppy was performed, finding a closure defect of the abdominal midline with viscera exposure (small intestine, liver, right kidney and spleen among others). The radiological evaluation showed the eventration of abdominal organs without clear differentiation between them, kyphosis in the thoracolumbar segment, lordosis in the lumbar portion and oligodactyly in the right posterior limb.
2
artículo
Publicado 2020
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The case of a 5-year-old crossbred female cat in her first gestation was presented for consultation. The cat had a stillborn present in the birth canal, which was extracted manually. A second puppy is expelled alive but was euthanized because of her clinical infeasibility. The two puppies presented a malformation in the abdominal region with exposure of some viscera, considered as Schistosomus reflexus syndrome. The radiological and necropsy diagnostic evaluation of the second puppy was performed, finding a closure defect of the abdominal midline with viscera exposure (small intestine, liver, right kidney and spleen among others). The radiological evaluation showed the eventration of abdominal organs without clear differentiation between them, kyphosis in the thoracolumbar segment, lordosis in the lumbar portion and oligodactyly in the right posterior limb.
3
artículo
Publicado 2012
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The white-tailed deer (Odocoileus virginianus peruvianus) is a ruminant of the family Cervidae that is managed as a game species in the Sauce Grande area of Coto de Caza El Angolo (CCEA), Piura, Peru. The aim of this study was to propose a health protocol for the white-tailed deer of CCEA as an essential component of their management work plans as well as to serve as a model for other wildlife in protected natural areas. For the development of this protocol a literature review was done on the species, along with five visits to CCEA for the evaluation of the area and the standardization of some procedures, where biological samples were collected from white-tailed deers and domestic mammals in the area for microbiologic analysis.
4
artículo
Publicado 2012
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The white-tailed deer (Odocoileus virginianus peruvianus) is a ruminant of the family Cervidae that is managed as a game species in the Sauce Grande area of Coto de Caza El Angolo (CCEA), Piura, Peru. The aim of this study was to propose a health protocol for the white-tailed deer of CCEA as an essential component of their management work plans as well as to serve as a model for other wildlife in protected natural areas. For the development of this protocol a literature review was done on the species, along with five visits to CCEA for the evaluation of the area and the standardization of some procedures, where biological samples were collected from white-tailed deers and domestic mammals in the area for microbiologic analysis.
5
artículo
Publicado 2022
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Objectives: To compare the rate disparity between outcomes (overall survival (OS), progression-free survival (PFS), and safety) of concurrent chemoradiation (cCRT) followed by durvalumab in two patient cohorts with locally advanced (LA) stage III non-small cell lung cancer (NSCLC), one non-Hispanic White (NHW), and the other Latin-American. Methods: A multicenter retrospective study was performed, including 80 Hispanic and 45 NHW LA stage III NSCLC patients treated with cCRT followed by durvalumab. Both cohorts were analyzed in terms of main outcomes (OS, PFS, and safety) and compared between them and with the PACIFIC trial population outcomes. The efficacy-effectiveness gap was assessed using an efficacy-effectiveness (EE) factor that was calculated by dividing each cohort median overall survival by the corresponding reference OS from the PACIFIC trial. In both cohorts, results of PD-L1...
6
artículo
Publicado 2021
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Background: Thymomas are a group of rare neoplasms of the anterior mediastinum. The objective of this study was to describe the demographics, clinical characteristics and treatment approaches in Latin America.Methods: This was a retrospective multicenter cohort study including patients with histologically proven thymomas diagnosed between 1997 and 2018. Demographics, clinicopathological characteristics and therapeutic outcomes were collected locally and analyzed in a centralized manner. Results: A total of 135 patients were included. Median age at diagnosis was 53 years old (19-84), 53.3% (n = 72) of patients were female and 87.4% had an ECOG performance score ranging from 0-1. A total of 47 patients (34.8%) had metastatic disease at diagnosis. Concurrent myasthenia gravis occurred in 21.5% of patients. Surgery was performed in 74 patients (54.8%), comprising 27 (20%) tumorectomies and 4...
7
artículo
Publicado 2022
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Background: Mutations in STK11 (STK11Mut) and, frequently co-occurring, KEAP1 mutations (KEAP1Mut) are associated with poor survival in metastatic Non-small Cell Lung Cancer (mNSCLC) patients treated with immunotherapy. However, there are limited data regarding the prognostic or predictive significance of these genomic alterations among Hispanics. Methods: This retrospective study analyzed a cohort of Hispanic patients (N = 103) diagnosed with mNSCLC from the US and seven Latin American countries (LATAM) treated with immune checkpoint inhibitors (ICI) alone or in combination as first-line (Cohort A). All cases were treated in routine care between January 2016 and December 2021. The main objectives were to determine the association of mutations in STK11 or KEAP1 in these patients’ tumors with overall (OS) and progression-free survival (PFS), presence of KRAS mutations, tumor mutational ...
