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artículo

Characteristics and outcomes of thymomas in Latin America: Results from over 10 years of experience (CLICaP-LATimus)

Publicado por
Martín, C, Enrico, D, Mas Lopez, Luis, Patane, AK, Arrieta, O, Soria, T, Cardona, AF, Ruiz-Patiño, A, Ruiz, R, Rioja, P, Lozano, S, Zatarain-Barrón, ZL, Barrón, F, Puparelli, C, Tsou, F, Corassa, MP, Freitas, HC, Cordeiro de Lima, VC, Rojas, L, Ordóñez-Reyes, C, Corrales, L, Sotelo, C, Rodríguez, J, Ricaurte, L, Ávila, J, Archila, P, Rosell, R, Cuello, M, Remon, J

Publicado 2021

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Background: Thymomas are a group of rare neoplasms of the anterior mediastinum. The objective of this study was to describe the demographics, clinical characteristics and treatment approaches in Latin America.Methods: This was a retrospective multicenter cohort study including patients with histologically proven thymomas diagnosed between 1997 and 2018. Demographics, clinicopathological characteristics and therapeutic outcomes were collected locally and analyzed in a centralized manner. Results: A total of 135 patients were included. Median age at diagnosis was 53 years old (19-84), 53.3% (n = 72) of patients were female and 87.4% had an ECOG performance score ranging from 0-1. A total of 47 patients (34.8%) had metastatic disease at diagnosis. Concurrent myasthenia gravis occurred in 21.5% of patients. Surgery was performed in 74 patients (54.8%), comprising 27 (20%) tumorectomies and 4...