Homozygous familial hypercholesterolemia (HFH) is a rare and life-threatening disease that can manifest as coronary artery disease or severe aortic stenosis before twenties. We present the case of a male adolescent who was hospitalized with a clinical diagnosis of HFH and severe aortic stenosis. He underwent aortic valve replacement with mechanical prosthesis and aortic annulus enlargement, and two aortocoronary bypasses were implanted due to an intraoperative complication. The patient evolved favourably and was discharged with combination therapy with high-intensity statins and ezetimibe.

La hipercolesterolemia familiar homocigota (HFH) es una enfermedad infrecuente y potencialmente mortal que se puede manifestar como enfermedad coronaria o estenosis aórtica severa antes de los 20 años de edad. Presentamos el caso de un adolescente de sexo masculino que fue hospitalizado con diagnóstico clínico de HFH y estenosis aórtica severa. Se le realizó cirugía de reemplazo de válvula aórtica con prótesis mecánica y ampliación de anillo, y se implantaron dos baipases aortocoronarios debido a una complicación intraoperatoria. El paciente evolucionó favorablemente y fue dado de alta con terapia combinada con estatinas de alta intensidad y ezetimibe.

Homozygous familial hypercholesterolemia (HFH) is a rare and life-threatening disease that can manifest as coronary artery disease or severe aortic stenosis before twenties. We present the case of a male adolescent who was hospitalized with a clinical diagnosis of HFH and severe aortic stenosis. He underwent aortic valve replacement with mechanical prosthesis and aortic annulus enlargement, and two aortocoronary bypasses were implanted due to an intraoperative complication. The patient evolved favourably and was discharged with combination therapy with high-intensity statins and ezetimibe.

Determina los factores predictores de mortalidad intrahospitalaria en pacientes con complicaciones mecánicas post infarto de miocardio en el Instituto Nacional Cardiovascular – INCOR. El presente estudio es de corte transversal retrospectivo. En Perú, en el 2021 se realizó un registro de complicaciones mecánicas en el Instituto nacional cardiovascular INCOR desde enero del 2017 a diciembre del 2021 donde se encontraron 37 complicaciones mecánicas post infarto de miocardio. No aplica realizar el cálculo del tamaño de la muestra porque el estudio incluirá a toda la población de pacientes con el diagnóstico de una complicación mecánica post infarto agudo de miocardio registrados desde las fechas de enero del 2017 hasta diciembre del 2023, ya que es una población pequeña. Se ha determinado que un paciente con complicaciones mecánicas post infarto de miocardio tiene malos res...

Objective. To determine the clinical characteristics, therapeutic and in-hospital mortality of patients with mechanical complications post myocardial infarction. Materials and methods. Observational, descriptive and retrospective study. We included patients >18 years old with a diagnosis of mechanical complication post myocardial infarction hospitalized at the Instituto Nacional Cardiovascular- INCOR in Lima -Peru, from January 1, 2017 to December 31, 2021. Variables like clinical characteristics, treatments, complications, and in-hospital mortality were studied. Results. We found 37 cases, with a predominance of males (73.0%) and a median age of 73 years old. The location of the myocardial infarction was 51.4% in the anterior wall and 43.2% in the inferior wall. The patients received reperfusion therapy with fibrinolysis in 5 cases (13.5%), coronary angioplasty in 5 (13.5%), and 73% ...

Objective. To determine the clinical characteristics, therapeutic and in-hospital mortality of patients with mechanical complications post myocardial infarction. Materials and methods. Observational, descriptive and retrospective study. We included patients >18 years old with a diagnosis of mechanical complication post myocardial infarction hospitalized at the Instituto Nacional Cardiovascular- INCOR in Lima -Peru, from January 1, 2017 to December 31, 2021. Variables like clinical characteristics, treatments, complications, and in-hospital mortality were studied. Results. We found 37 cases, with a predominance of males (73.0%) and a median age of 73 years old. The location of the myocardial infarction was 51.4% in the anterior wall and 43.2% in the inferior wall. The patients received reperfusion therapy with fibrinolysis in 5 cases (13.5%), coronary angioplasty in 5 (13.5%), and 73% ...

Objetivo. Determinar las características clínicas, terapéuticas y la mortalidad intrahospitalaria de los pacientes con complicaciones mecánicas posinfarto de miocardio (IM). Materiales y métodos. Estudio observacional, descriptivo y retrospectivo. Se incluyó a pacientes > 18 años con diagnóstico de complicación mecánica pos-IM hospitalizados en el Instituto Nacional Cardiovascular (INCOR) en Lima-Perú, del 1 de enero de 2017 hasta el 31 de diciembre de 2021. Se estudiaron variables clínicas, terapéuticas, complicaciones y mortalidad intrahospitalaria. Resultados. Se registraron 37 casos, con predominio del sexo masculino (73,0%) y mediana de edad 73 años. La localización del infarto fue en la pared anterior (51,4%) y en la pared inferior (43,2%). Los pacientes recibieron fibrinólisis en cinco casos (13,5%); angioplastia coronaria en cinco casos (13,5%), y el 73% recibiero...

A clinically significant case is reported, as it is the first to be published in the region. It refers to a patient who was admitted to the hospital through the emergency department after four days ofillness. The initial clinical presentation included lower limb edema and functional class II dyspnea, which progressed to class IV. A 12-lead electrocardiogram showed atrial tachycardia with a heart rate of 187 bpm. Sequential administration of adenosine, verapamil and electrical cardioversion was unsuccessful. Subsequently, amiodarone was given, leading to the restoration of sinus rhythm. On the second day of hospitalization, the patient developed frequent ventricular ectopic beats and episodes of supraventricular ectopic beats, for which amiodarone was continued. On the third day, he presented with an increased frequency of ventricular ectopy and non-sustained ventricular tachycardia, whic...