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                  1900 has been studied cells frotises 50 cases of in situ cervical cancer and 520 cells frotises of 12 cases of invasive cervical cancer, all confirmed histologically. It was performed measurements of each cell and its nucleus and described morphological characteristics and tintoreales nucleus and cytoplasm. It concludes that while there are no cancer cells pathognomonic of cancer in situ, allowing make such a diagnosis for purely cytological means, however smear intra-epithelial carcinoma is usually very suggestive and allows the cytologist, in most cases, advance the possibility of such a diagnosis, which must be confirmed histologically.               
            
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                 artículo
            
         
                  1900 has been studied cells frotises 50 cases of in situ cervical cancer and 520 cells frotises of 12 cases of invasive cervical cancer, all confirmed histologically. It was performed measurements of each cell and its nucleus and described morphological characteristics and tintoreales nucleus and cytoplasm. It concludes that while there are no cancer cells pathognomonic of cancer in situ, allowing make such a diagnosis for purely cytological means, however smear intra-epithelial carcinoma is usually very suggestive and allows the cytologist, in most cases, advance the possibility of such a diagnosis, which must be confirmed histologically.               
            
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                                                                           Publicado 2004                                                                                    
                        
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                  Fourteen year-old male patient referred from Huancayo who presented one month gastric intolerance, jaundice, fever and a lymph proliferative syndrome. Laboratory tests revealed severe pancytopenia due to phagocytosis. Haematologic and anatomy-pathology diagnosis was human malignant histiocytosis. We present this case due to its low frequency and the emergency character of the disease.               
             
   
   
             
            