Juglans neotropica Diels "peruvian walnut" is a tree that grows in jungle, in areas ofmontane and montane rain forest whose leaves have antioxidant, astringent, antibacterial andantiseptic properties. The objective was to determine the antioxidant activity of a standardizedhydroalcoholic extract of Juglans neotropica Diels leaves. Leaves from Huandoval district,Pallasca province, Ancash Region were used. Standardization analysis included determinationof moisture, physicochemical parameters, solubility march, phytochemical screening, andthin layer chromatography; antioxidant activity was determined by the DPPH inhibitionassay. In phytochemical screening there was a greater concentration of phenolic compoundsand antioxidant activity was at 25 and 35 μg/mL respectively, with an IC 50 of 12.82 μg/mL.In conclusion, the standardized hydroalcoholic extract from Juglans neotropica Diels leaves...

Objetivo: determinar la actividad gastroprotectora del extracto hidroalcohólico de las hojas de Juglans neotropica Diels “nogal peruano”. Diseño: estudio prospectivo experimental. Materiales biológicos: extracto de hojas de Juglans neotropica Diels y ratas albinas macho raza Sprague Dawley. Métodos: se determinó los metabolitos secundarios con los reactivos específicos. La cuantificación del compuesto fenólico mayoritario se determinó por el método de Folin Ciocalteu. Para la evaluación de la actividad gastroprotectora, se empleó el modelo de inducción de úlceras gástricas por etanol 96°, se administró el extracto a dosis de 50, 250 y 500 mg/kg. Fármacos patrones utilizados: omeprazol 20 mg/kg y sucralfato 3 ml/kg. La evaluación macroscópica fue mediante la escala de Alada et al modificada y la de Marhuenda. Para el estudio histopatológico, los tejidos se conserv...

The aguaymanto is a native species of the Peruvian highland, which has a tiny fruit that disagrees with its greatness and nutritional therapy. The present investigation had as objetive to assess and compare the total polyphenol content by the Folin-Ciocalteu method and antioxidant capacity of the fruits of Physalis peruviana L., from Huánuco, Junín, Ancash y Cajamarca by the method of the DPPH (1,1-diphenyl-2-picril-hidrazilo). The fruit coming from Huánuco presented a higher content of phenolic compounds expressed as 149.3 ± 1.62 mg/Eq of gallic acid/100g fruit. In addition, greater antioxidant capacity obtaining as inhibitory concentration IC50 1.86 mg/mL, compared with the fruits from Junín, Ancash y Cajamarca; and it would be a good source of consumption in benefit for the health.