Introducción. La malaria es un problema serio debido al aumento de la incidencia y la expansión de la población. El aumento de los casos de malaria en el Perú hizo necesaria la identificación de las personas con infección crónica. Objetivos: Conocer las características epidemiológicas de los residentes del distrito Chóchope y determinar la presencia y la prevalencia de Plasmodium sp. en pacientes con malaria asintomática. El estudio: Estudio mediante la técnica de gota gruesa de 227 personas, siguiendo los procedimientos del Manual de Procedimientos de Laboratorio para el Diagnóstico de Malaria del Instituto Nacional de Salud. Hallazgos: No se identificaron pacientes asintomáticos mediante la técnica de gota gruesa, sin embargo se encontró a un paciente mediante métodos moleculares como la Reacción en Cadena de la Polimerasa (PCR). Se determinó que la actividad la...

Background: Plasmodium vivax remains a challenge in Peru. The high heterogeneity of its transmission has limited the intervention measures based on global and generalized epidemiological information at medium and long term. Population genetic tools may provide information on the spatial heterogeneity of transmission by linking parasite genetic patterns with epidemiological information. Methods: The genetic diversity and population structures from three settlements located in the Peruvian Amazon, Cahuide (CAH), Lupuna (LUP) and Santa Emilia (STE) were measured on samples collected from September 2012 to March 2015. Results: A total of 777 P. vivax mono- infections were genotyped. LUP showed the lowest proportion of polyclonal infections (0.197) and genetic diversity (Hexp 0.544 ± 0.0012). Moreover, in this study area results showed a significant increment of polyclonal infections and Hex...

Plasmodium vivax is the main cause of malaria in the Peruvian Amazon and Mazan is considered one of its districts with high risk of malaria transmission. In this site, previous studies has described P. vivax transmission as heterogenic and has suggested that its prevalence is influenced by factors linked to human mobilization. However, the contribution of this factor have not been assessed yet. Population genetic tools provide information on the individual contribution of the factors that favor the transmission and evaluate the demographic patterns of dispersion of the parasite populations which are influenced by the human mobilization. In order to evaluate contribution of human mobilization to malariatransmission in Mazan, in this work we use a Bayesian framework to identify genetic sub-populations in each basin and to discriminate between endogenous and imported cases. Socio-demographi...