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artículo
Publicado 2017
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The incidence of malaria due both to Plasmodium falciparum and Plasmodium vivax in the Peruvian Amazon has risen in the past 5 years. This study tested the hypothesis that the maintenance and emergence of malaria in hypoendemic regions such as Amazonia is determined by submicroscopic and asymptomatic Plasmodium parasitaemia carriers. The present study aimed to precisely quantify the rate of very-low parasitaemia carriers in two sites of the Peruvian Amazon in relation to transmission patterns of P.vivax and P.falciparum in this area. Methods: This study was carried out within the Amazonian-ICEMR longitudinal cohort. Blood samples were collected for light microscopy diagnosis and packed red blood cell (PRBC) samples were analysed by qPCR. Plasma samples were tested for total IgG reactivity against recombinant PvMSP-10 and PfMSP-10 antigens by ELISA. Occupation and age 10 years and greater...
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artículo
Publicado 2020
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The pandemic of COVID-19 has shown that the information disseminated through peer-reviewed journals and accompanying online data sets is vital for decision-makers. However, we are currently seeing several deficiencies in open-data sharing mechanisms globally, and in particular Latin American countries, and therefore, this highlights the need for open access to data. Latin American and Caribbean countries have remarkable initiatives to publish ‘open-access’ science through the Scientific Electronic Library On-line (SciELO),1 comprising a network of 16 national open-access journal collections and included more than 1350 active titles. The SciELO collections publish the best journals from the most research-productive countries from Latin America and the Caribbean region. Moreover, the ‘LA Referencia’2 is a Latin American network of 10 countries whose open-access repositories share i...
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Background: Peru recorded one of the world’s highest COVID-19 mortality rates, with nearly 4.5 million reported cases and 220,000 deaths by March 2024. Understanding the emergence and spread of SARS-CoV-2 variants in this context is key to informing effective public health responses. This study describes the genomic diversity, transmission dynamics, and geographic spread of SARS-CoV-2 in Peru from 2020 to 2024. Methods: We analyzed nearly 50,000 high-quality public SARS-CoV-2 genome sequences collected nationwide between March 2020 and March 2024. Phylogeographic and mutational analyses were performed to identify variant lineages, trace their origins, and map viral movements within and beyond Peru. Results: We show that Peru’s epidemic waves were shaped by the emergence of locally evolved variants, including Lambda (C.37), Gamma (P.1.12), and Omicron (XBB.2.6 and DJ.1) sub-lineages. ...
