El presente trabajo de investigación denominado: “Aula Invertida para el dominio del Idioma Ingles en estudiantes de secundaria de una institución educativa distrito La Victoria Chiclayo”; se realizó con el fin de mejorar el dominio del idioma Inglés en los estudiantes de la institución. Se utilizó un enfoque cuantitativo de tipo descriptivo propositivo de diseño no experimental. Se aplicó el test diagnóstico de nivel intermedio debidamente adaptado como instrumento de evaluación para medir si los estudiantes llegaban a dicho nivel. Se trabajó con una muestra de 52 estudiantes de quinto año de secundaria. Los resultados obtenidos nos muestran que los estudiantes presentan dificultades con respecto a la comprensión lectora, pues hubo un 28.8% de preguntas acertadas mientras que un 79.2% fue incorrecto. De otro lado, en la producción escrita un hubo 7.7% de respuestas res...

“Introduction: Anxiety can affect front-line healthcare workers (HCWs) during the COVID-19 pandemic mainly in settings with influencing factors. Living with COVID-19 patients in hospital settings could affect mental health during lockdown. The present study aimed to estimate the anxiety levels of HCWs of the care center for COVID-19 Villa Panamericana during the first outbreak of COVID-19 in Peru. Methods: This is a descriptive and correlational study. Ninety-six HCWs were enrolled in this study (mean age 30±5.6 years). The care center for COVID-19 Villa Panamericana houses COVID-19 patients and HCWs in the same environment. We used the 14-item Hamilton anxiety rating scale questionnaire. Professionals were interviewed directly at the VP-19 rest towers. SPSS V.23 were used to analyze the data. Results: Fifty-four (56.3%) were male and the most frequent age group was 26-35 years (81.3%...

“Introduction: Anxiety can affect front-line healthcare workers (HCWs) during the COVID-19 pandemic mainly in settings with influencing factors. Living with COVID-19 patients in hospital settings could affect mental health during lockdown. The present study aimed to estimate the anxiety levels of HCWs of the care center for COVID-19 Villa Panamericana during the first outbreak of COVID-19 in Peru. Methods: This is a descriptive and correlational study. Ninety-six HCWs were enrolled in this study (mean age 30±5.6 years). The care center for COVID-19 Villa Panamericana houses COVID-19 patients and HCWs in the same environment. We used the 14-item Hamilton anxiety rating scale questionnaire. Professionals were interviewed directly at the VP-19 rest towers. SPSS V.23 were used to analyze the data. Results: Fifty-four (56.3%) were male and the most frequent age group was 26-35 years (81.3%...

“Introduction: Scientific consultation sources is essential in the quality of information during medical training worldwide. The sources of consultation should provide quality information to students who begin with clinical courses; however, it is unknown how and where students seek data in all medical schools in Peru. In this study, we determine the most frequent sources of scientific consultation of medical students at Norbert Wiener University. Materials and methods: We conducted a survey-based observational study in 148 volunteers (mean age 22.1±5.4 years) during 2019. A 21-items questionnaire was divided into three components: demographic data (10 questions), scientific consultation sources (7 questions), and Information search engines (4 questions). Results: Eighty (54.1%) students were between 20-30 years, and 26.8% worked < 20 hours per week. The scientific search sources cons...

“Introduction: Scientific consultation sources is essential in the quality of information during medical training worldwide. The sources of consultation should provide quality information to students who begin with clinical courses; however, it is unknown how and where students seek data in all medical schools in Peru. In this study, we determine the most frequent sources of scientific consultation of medical students at Norbert Wiener University. Materials and methods: We conducted a survey-based observational study in 148 volunteers (mean age 22.1±5.4 years) during 2019. A 21-items questionnaire was divided into three components: demographic data (10 questions), scientific consultation sources (7 questions), and Information search engines (4 questions). Results: Eighty (54.1%) students were between 20-30 years, and 26.8% worked < 20 hours per week. The scientific search sources cons...

“Background: Quality of life (QoL) is a multifactorial concept on the perception of the individual’s wellbeing underpinned by environmental, psychological, and physical factors. Several studies have shown changes in QoL in the COVID-19 pandemic and may be due to increases in mortality rates, however, no study has investigated this among Peruvian jungle dwellers. Here, we have sought to estimate the QoL of individuals before and after the increase in cases and deaths from COVID-19. Methods: A questionnaire-based longitudinal study was conducted in 102 inhabitants (mean 40.75 ± 7.49 years). The Spanish version of the WHOQOL-BREF was used in two stages: April and June. The first stage was accomplished before the first confirmed case of COVID-19, and the second stage was when the daily mortality rate was 3.5% with an incidence of 87%. Results: Sixty (54.8%) participants were women, 67 (...

“Introduction: The follow-up of squamous intraepithelial lesions (SIL) allows us to understand their progression and regression, however squamous cell atypia (ASC) can generate confusing follow-up results. We aimed to describe the evolution of ASC and SIL during cyto-histopathological follow-up in a tertiary-care hospital. Materials and methods: we conducted a retrospective study during 2016 in 156 Papanicolaou test (PAP) results under three models: 1) with ≥1 PAP and biopsies, 2) 1 PAP followed by ≥1 biopsy, and 3) ≥1 PAP and a confirmatory biopsy. Progression was defined as ASCUS to low-grade SIL (LSIL) or higher, and LSIL to high-grade SIL (HSIL) or higher; and regression as HSIL to LSIL or lower; and LSIL to ASCUS or lower. Results: In PAP, 57 (36.5%) cases were ASC and in histopathology 56 (39.9%) cases of grade 1 cervical intraepithelial neoplasia. Twenty-nine (18.6%) resul...

Introduction: The follow-up of squamous intraepithelial lesions (SIL) allows us to understand their progression and regression, however squamous cell atypia (ASC) can generate confusing follow-up results. We aimed to describe the evolution of ASC and SIL during cyto-histopathological follow-up in a tertiary-care hospital. Materials and methods: we conducted a retrospective study during 2016 in 156 Papanicolaou test (PAP) results under three models: 1) with ≥1 PAP and biopsies, 2) 1 PAP followed by ≥1 biopsy, and 3) ≥1 PAP and a confirmatory biopsy. Progression was defined as ASCUS to low-grade SIL (LSIL) or higher, and LSIL to high-grade SIL (HSIL) or higher; and regression as HSIL to LSIL or lower; and LSIL to ASCUS or lower. Results: In PAP, 57 (36.5%) cases were ASC and in histopathology 56 (39.9%) cases of grade 1 cervical intraepithelial neoplasia. Twenty-nine (18.6%) results ...

“Background: Quality of life (QoL) is a multifactorial concept on the perception of the individual’s wellbeing underpinned by environmental, psychological, and physical factors. Several studies have shown changes in QoL in the COVID-19 pandemic and may be due to increases in mortality rates, however, no study has investigated this among Peruvian jungle dwellers. Here, we have sought to estimate the QoL of individuals before and after the increase in cases and deaths from COVID-19. Methods: A questionnaire-based longitudinal study was conducted in 102 inhabitants (mean 40.75 ± 7.49 years). The Spanish version of the WHOQOL-BREF was used in two stages: April and June. The first stage was accomplished before the first confirmed case of COVID-19, and the second stage was when the daily mortality rate was 3.5% with an incidence of 87%. Results: Sixty (54.8%) participants were women, 67 (...

“Introduction: Preeclampsia is the major cause of maternal death in Latin America, which presents with hypertension and proteinuria after 20 weeks of gestation, increasing the levels of inflammatory markers.We aimed to determine the ratio of LDH and protein/creatinine index (PCI) in Peruvian pregnant women with preeclampsia at the Hospital Nacional Docente Madre Niño San Bartolomé in 2017. Materials and methods: we conducted a cross-sectional study in 3415 pregnant preeclamptic women without eclampsia or HELLP syndrome. The kinetic method was used to determine urine creatinine (mg/dl), the turbidimetric method for protein quantification (mg/dl), and the kinetic method for LDH (U/L). Kendall’s Tau-b correlation and non-paired t-test were used. Results: Of the total, 168 (4.9%) had a clinical diagnosis of preeclampsia with a higher frequency in the 25-35 age group (41.7%). We observe...

Background and Aims:COVID‐19 is a pandemic disease that can lead to alteredlung function, systemic inflammatory events, and altered coagulation. During severestages of the disease, changes in coagulation homeostasis increase, leading tothrombosis, and increased risk of death. In this cross‐sectional study, we aimedto assess coagulation markers by COVID‐19 severity in Peruvian adults.Methods:During the second wave of infections, we included 186 adults diagnosedwith COVID‐19 (mean age 53.3 ± 16.3 years). Patients were divided into mild,moderate, and severe stages of COVID‐19, and coagulation markers includedprothrombin time (PT), activated partial prothrombin time (aPTT), fibrinogen,D‐dimer, and platelet count.Results:Of the total, 120 (64.5%) were males and 39 (21%) were in the intensivecare unit. We determine 104 (55.9%), 43 (24.7%), and 36 (19.4%) patients in mild,moderate,...

“Introduction: Preeclampsia is the major cause of maternal death in Latin America, which presents with hypertension and proteinuria after 20 weeks of gestation, increasing the levels of inflammatory markers.We aimed to determine the ratio of LDH and protein/creatinine index (PCI) in Peruvian pregnant women with preeclampsia at the Hospital Nacional Docente Madre Niño San Bartolomé in 2017. Materials and methods: we conducted a cross-sectional study in 3415 pregnant preeclamptic women without eclampsia or HELLP syndrome. The kinetic method was used to determine urine creatinine (mg/dl), the turbidimetric method for protein quantification (mg/dl), and the kinetic method for LDH (U/L). Kendall’s Tau-b correlation and non-paired t-test were used. Results: Of the total, 168 (4.9%) had a clinical diagnosis of preeclampsia with a higher frequency in the 25-35 age group (41.7%). We observe...

Objective To ensure the health of newborns, it is necessary to perform high-quality diagnostic tests. The TORCH panel is a set of tests that identifies infectious pathogens such as Toxoplasma (Toxo) and Cytomegalovirus (CMV) that are common in low-setting populations. We performed TORCH panel quality planning using six sigma in a reference laboratory at Peru. Results This was a cross-sectional study. TORCH tests include Toxo, Rubella, CMV, and Herpes. We processed all samples by fourth-generation ELISA on the GEMINI XCR200 analyzer (Diatron, Budapest, Hungary). We obtained the imprecision from the annual data of the external quality assessment plan and we used the CLSI EP12-A3 guideline. In a total of 44,788 analyses, the average imprecision was 3.69 ± 1.47%, and CMV had lower imprecision (2.3 and 2.6% for IgM and IgG, respectively). Quality planning of the TORCH panel allowed estim...

“Fish farms are one of the principal food industries located in peri-urban and rural communities that use available resources to ensure the quality of their products. However, trout can suffer from bacterial infections affecting the sector and being a key component of human health risk. We aimed to identify and characterize Enterobacteriaceae in 46 trout (Oncorhynchus mykiss) in two fish farms in Lima, Peru. Adult trouts older than seven weeks (> 200 grams weight) were included. Cultures were performed in duplicate (n=192 trials) with swabs from the squamous surface and visceral cavity. The isolates were identified with the Vitek® 2 Compact system, and the minimum inhibitory concentrations (MIC) were interpreted with the CLSI VET 03-A guide. At El Molino and El Angelito fish farms, 66 (68.8%) and 57 (59.4%) isolates were obtained. The most frequently isolated species were Escherichia ...

“Objective: To ensure the health of newborns, it is necessary to perform high-quality diagnostic tests. The TORCH panel is a set of tests that identifes infectious pathogens such as Toxoplasma (Toxo) and Cytomegalovirus (CMV) that are common in low-setting populations. We performed TORCH panel quality planning using six sigma in a reference laboratory at Peru. Results: This was a cross-sectional study. TORCH tests include Toxo, Rubella, CMV, and Herpes. We processed all samples by fourth-generation ELISA on the GEMINI XCR200 analyzer (Diatron, Budapest, Hungary). We obtained the imprecision from the annual data of the external quality assessment plan and we used the CLSI EP12-A3 guideline. In a total of 44,788 analyses, the average imprecision was 3.69±1.47%, and CMV had lower imprecision (2.3 and 2.6% for IgM and IgG, respectively). Quality planning of the TORCH panel allowed estimat...

COVID- 19 patients are prone to coinfections during their hospitalization. These coinfections are challenging as they involve longer hospital stays, high costs, and higher risk of mortality. Here, we present a case of a patient with multi- infection by resistant parasites, fungi, and bacteria during his hospitalization in a hospital in Lima, Peru

Background: The effect of cannabis on cholesterol and lipid balance has been reported for decades. However, there are conflicting reports on the reduction of low-density lipoprotein (LDL-C) and total cholesterol. The purpose of this study was to determine the immediate changes of Cannabis spp. consumption by pyrolytic route in heavy users. Methods: A cross-sectional study on 20 Peruvian heavy cannabis users (mean age: 31 ± 9.5 years). The inclusion criteria were males with an average weight of 50–70 kg, normal BMI, and having used cannabis, without association with other drugs, for at least one year with a high frequency per week (use: 4–7 days/week). High-density lipoprotein (HDL-C), LDL-C, and total cholesterol were evaluated 30 and 120 min after the administration of Cannabis spp. (~0.2 g by inhalation). Results: Of the total 12 (60%), 10 (50%), and 11 (55%) had desirable total c...

“Background: The effect of cannabis on cholesterol and lipid balance has been reported for decades. However, there are conflicting reports on the reduction of low-density lipoprotein (LDL-C) and total cholesterol. The purpose of this study was to determine the immediate changes of Cannabis spp. consumption by pyrolytic route in heavy users. Methods: A cross-sectional study on 20 Peruvian heavy cannabis users (mean age: 31 ± 9.5 years). The inclusion criteria were males with an average weight of 50–70 kg, normal BMI, and having used cannabis, without association with other drugs, for at least one year with a high frequency per week (use: 4–7 days/week). High-density lipoprotein (HDL-C), LDL-C, and total cholesterol were evaluated 30 and 120 min after the administration of Cannabis spp. (~0.2 g by inhalation). Results: Of the total 12 (60%), 10 (50%), and 11 (55%) had desirable tota...

“Background: The effect of cannabis on cholesterol and lipid balance has been reported for decades. However, there are conflicting reports on the reduction of low-density lipoprotein (LDL-C) and total cholesterol. The purpose of this study was to determine the immediate changes of Cannabis spp. consumption by pyrolytic route in heavy users. Methods: A cross-sectional study on 20 Peruvian heavy cannabis users (mean age: 31 ± 9.5 years). The inclusion criteria were males with an average weight of 50–70 kg, normal BMI, and having used cannabis, without association with other drugs, for at least one year with a high frequency per week (use: 4–7 days/week). High-density lipoprotein (HDL-C), LDL-C, and total cholesterol were evaluated 30 and 120 min after the administration of Cannabis spp. (~0.2 g by inhalation). Results: Of the total 12 (60%), 10 (50%), and 11 (55%) had desirable tota...

“Introduction: As face-to-face medical education was restricted during the pandemic; digital tools have been deployed to continue education showing a good educational impact in most countries. However, the perception of medical students in Peru on eLearning has not yet been investigated. This study assessed the perception of 440 medical students from two national universities in Peru on the characteristics and limitations of eLearning during 2021. Materials and methods: We conducted a cross-sectional study using the self-administered survey Encuesta Virtual en Tiempos de COVID-19 (EVI-CV19) on students between the second and sixth medical year of the Universidad Nacional Mayor de San Marcos (UNMSM) and the Universidad Nacional San Luis Gonzaga (UNSLG, n=325). Results: The majority of students were under 30 years of age (93.9% vs. 97.2%, p=0.084), and female (67% vs. 64%, p=0.107). Of t...