Public health officials around the world are extremely concerned about the global outbreak of monkeypox (MPX), which has been claimed to have originated in Africa. As a result, studies into the origins and reasons behind the outbreak’s rapid spread have been sped up. The goal of the current investigation is to determine whether the monkeypox virus (MPXV) is present in seminal fluid samples from MPX cases that have been verified. Up until 6 January 2023, PubMed, Scopus, Web of Science, Embase, and ScienceDirect databases were used to conduct a thorough evaluation of the literature. The search technique returned a total of 308 items. Fourteen studies reporting the presence of MPXV in the seminal fluid of MPX-confirmed cases were included after the duplicates (n = 158) and searches by title, abstract, and full text were eliminated. In 84 out of the 643 confirmed MPX cases (13.06% or n = 6...

Objective. We systematically assessed the efficacy of tunnel technique (TUN) vs. coronally advanced flap (CAF) in the management of multiple gingival recession defects in adults. Methods. Five databases were searched until September 2021 for randomized controlled trials (RCTs) assessing TUN vs. CAF; grafts of interest were acellular dermal matrix (ADM) and connective tissue graft (CTG). Primary outcomes were root coverage (RC) and complete root coverage (CRC). Secondary outcomes were clinical attachment level (CAL), keratinized tissue width (KTW), probing depth (PD), and recession coverage (REC). Effect measures were risk ratio (RR) or mean difference (MD) with their confidence intervals (95% CI). Inverse variance methods and random-effects model meta-analyses were used. Subgroup analyses by the type of graft were performed. Quality of evidence was assessed using GRADE methodology. Resul...

Public health officials around the world are extremely concerned about the global outbreak of monkeypox (MPX), which has been claimed to have originated in Africa. As a result, studies into the origins and reasons behind the outbreak’s rapid spread have been sped up. The goal of the current investigation is to determine whether the monkeypox virus (MPXV) is present in seminal fluid samples from MPX cases that have been verified. Up until 6 January 2023, PubMed, Scopus, Web of Science, Embase, and ScienceDirect databases were used to conduct a thorough evaluation of the literature. The search technique returned a total of 308 items. Fourteen studies reporting the presence of MPXV in the seminal fluid of MPX-confirmed cases were included after the duplicates (n = 158) and searches by title, abstract, and full text were eliminated. In 84 out of the 643 confirmed MPX cases (13.06% or n = 6...

Malformations are important causes of infant mortality, chronic disease and disability in many countries, causing 3.2 million disabilities per year. The VATERL association includes vertebral defects, anal atresia, tracheoesophageal fistula and renal dysplasia, as well as limb abnormalities. This case report aims to provide the general characteristics of the VACTERL association and discuss other cases found in the medical literature. This is the case of a female newborn delivered at 35 weeks of pregnancy with severe respiratory distress, who was admitted to the neonatal ICU due to hemodynamic decompensation. She had a history of bilateral polycystic kidney disease found by ultrasound at 25 weeks of pregnancy. A physical examination showed vaginal agenesis and imperforate anus. Atelectasis, cardiomegaly and dextroposition of the cardiac silhouette were observed in a radiography. The patien...

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Objetive. The critical reading of scientific articles allows the medical community, above all, to improve the context of decision making. The great amount of scientific production worldwide makes use of observational studies, however, a significant proportion is not useful for decision making, not because of its methodological limitations but because of errors in its application. Many studies published in relation to coronavirus 2019 disease have limitations and require statistical, epidemiological and clinical tools to be able to assess them and incorporate them into the practice of evidence-based medicine. In this review, we analyze the different observational research designs and with the help of examples we will see the different steps in the research process.

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Objective: To identify the factors associated with insomnia in health professionals of a public hospital in Trujillo, Peru. Materials and methods: The Athens Insomnia Scale (AIS) was administered to 220 health professionals. The chi-square test and Student's t-test were used. In addition, the multivariate analysis was performed to identify the variables associated with insomnia. Results: It was demonstrated that there is less risk of insomnia in professionals under 38 years of age (OR 0.77; 95 % CI 0.68 – 0.87; p < 0.05). There is more risk of insomnia in cases of work overload (OR 4; 95 % CI 1.22 – 9.73; p < 0.05),night shifts (OR 3.12; 95 % CI 1.01 – 9.73; p < 0.05), job tenure of more than 7 years in the hospital (OR 1.50; 95 % CI 1.22 – 1.85; p < 0.001) and low back pain (OR 11.28; 95 % CI 3.61 – 35.28; p < 0.05), the latter being the variable with the highes...

“Objective. We systematically assessed the efficacy of tunnel technique (TUN) vs. coronally advanced flap (CAF) in the management of multiple gingival recession defects in adults. Methods. Five databases were searched until September 2021 for randomized controlled trials (RCTs) assessing TUN vs. CAF; grafts of interest were acellular dermal matrix (ADM) and connective tissue graft (CTG). Primary outcomes were root coverage (RC) and complete root coverage (CRC). Secondary outcomes were clinical attachment level (CAL), keratinized tissue width (KTW), probing depth (PD), and recession coverage (REC). Effect measures were risk ratio (RR) or mean difference (MD) with their confidence intervals (95% CI). Inverse variance methods and random-effects model meta-analyses were used. Subgroup analyses by the type of graft were performed. Quality of evidence was assessed using GRADE methodology. Re...

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“: Introduction: Rabies is caused by a virus belonging to the genus Lyssavirus and family Rhabdoviridae, which can infect any mammal including humans. Hematophagous, fructivorous, and insectivorous bats have become the main reservoir of sylvatic rabies in Latin America. In the sylvatic cycle, hematophagous bats are usually the main reservoir. In contrast, dogs and cats fulfil this critical role in the urban cycle. However, in rural areas, the most affected animals are bovines. They show clinical signs such as behavioural changes, hypersalivation, muscle tremors, spasms caused by extensive damage to the central nervous system, and death from respiratory paralysis. Objective: To describe the spatiotemporal distribution of bovine rabies in Colombia from 2005 to 2019. Methods: Retrospective cross-sectional descriptive observational study, based on the monthly reports of the Colombian Agric...

Objetive: The present study focused on determining if the hemoglobin difference of the third and first trimester of gestation greater than - 1 (decreased hemoglobin delta) is a risk factor for low birth weight in term newborns at Hospital Belen from Trujillo. Material and Methods: We performed a retrospective cohort study in which 218 newborns were included according to the selection criteria. The patients were divided into two group of patients with decreased and non-decreased maternal hemoglobin delta: applying the relative risk and the statistical chi test-square. Results: The frequency of low birth weight in pregnant women with decreased hemoglobin delta was 32/109 = 29%; the frequency of low birth weight in pregnant women with undiminished delta hemoglobin was 18/109 = 17%. Declined maternal hemoglobin delta is a risk factor for low birth weight with a relative risk of 1.78 [CI: 95%...

“El objetivo de este estudio fue evaluar la eficacia de los programas de tratamiento para la ciberadicción en niños y adolescentes. Material y Métodos: Se realizó la búsqueda en cinco bases de datos. Se seleccionaron ensayos controlados aleatorizados (ECA) o estudios de cohorte que evaluaron la eficacia de programas de tratamiento para la ciberadicción en niños y adolescentes. El desenlace primario fue la disminución de las horas en uso del internet. Para el meta-análisis, se utilizó el modelo de efectos aleatorios con método de varianza inversa. Resultados: Se identificaron siete artículos que fueron incluidos en la revisión sistemática (3 Ensayos controlados aleatorizados y 4 cohortes retrospectivas), con un total de 2396 participantes. La edad media fue de 14 años (SD 1.96). La duración del tratamiento entre todos los estudios publicados varió entre 4 días hasta lo...

Introduction: The objective of this study was to evaluate the efficacy of treatment programs for cyberaddiction in children and adolescents. Material and Methods: Five databases were searched. Randomized controlled trials (RCTs) or cohort studies that evaluated the efficacy of treatment programs for cyberaddiction in children and adolescents were selected. The primary outcome was a decrease in hours of Internet use. For the meta-analysis, the random effects model with inverse variance method was used. Results: Seven articles were identified and included in the systematic review (3 randomized controlled trials and 4 retrospective cohorts), with a total of 2396 participants. The mean age was 14 years (SD 1.96). The duration of treatment among all published studies ranged from 4 days to 3 months. Cyberaddiction treatments were found to reduce hours of internet connection by 1.18 hours per w...

“Introduction: Eastern equine encephalitis virus (EEEV) and Venezuelan equine encephalitis virus (VEEV) viruses are zoonotic pathogens affecting humans, particularly equines. These neuroarboviruses compromise the central nervous system and can be fatal in different hosts. Both have significantly influenced Colombia; however, few studies analyse its behaviour, and none develop maps using geographic information systems to characterise it. Objective: To describe the temporalspatial distribution of those viruses in Colombia between 2008 and 2019. Methods: Retrospective cross-sectional descriptive study, based on weekly reports by municipalities of the ICA, of the surveillance of both arboviruses in equines, in Colombia, from 2008 to 2019. The data were converted into databases in Microsoft Access 365®, and multiple epidemiological maps were generated with the Kosmo RC1®3.0 software coupl...

“: Introduction: Eastern equine encephalitis virus (EEEV) and Venezuelan equine encephalitis virus (VEEV) viruses are zoonotic pathogens affecting humans, particularly equines. These neuroarboviruses compromise the central nervous system and can be fatal in different hosts. Both have significantly influenced Colombia; however, few studies analyse its behaviour, and none develop maps using geographic information systems to characterise it. Objective: To describe the temporalspatial distribution of those viruses in Colombia between 2008 and 2019. Methods: Retrospective cross-sectional descriptive study, based on weekly reports by municipalities of the ICA, of the surveillance of both arboviruses in equines, in Colombia, from 2008 to 2019. The data were converted into databases in Microsoft Access 365®, and multiple epidemiological maps were generated with the Kosmo RC1®3.0 software cou...

“Introduction: A significant antibiotic prescribing pattern associated with the COVID-19 pandemic has been described. Multiple protocols included empirical antimicrobials, leading to a substantial increase in antimicrobial consumption in medical care. A higher mortality rate is described among patients diagnosed with COVID-19 who received antibiotics. Objectives: To determine the association between the use of antibiotics and the development of acute renal injury in patients infected with SARS-CoV-2 in patients treated at the Hospital II EsSalud de Ucayali, 2021. Methods: A cross-sectionalanalytical study was conducted, evaluating the medical records of patients admitted to the intensive care unit between July 2020 and July 2021. For the statistical analysis, measures of central tendency and dispersion, statistical hypothesis contrast tests were used in relation to acute kidney injury ...

“Introduction: A significant antibiotic prescribing pattern associated with the COVID-19 pandemic has been described. Multiple protocols included empirical antimicrobials, leading to a substantial increase in antimicrobial consumption in medical care. A higher mortality rate is described among patients diagnosed with COVID-19 who received antibiotics. Objectives: To determine the association between the use of antibiotics and the development of acute renal injury in patients infected with SARS-CoV-2 in patients treated at the Hospital II EsSalud de Ucayali, 2021. Methods: A cross-sectionalanalytical study was conducted, evaluating the medical records of patients admitted to the intensive care unit between July 2020 and July 2021. For the statistical analysis, measures of central tendency and dispersion, statistical hypothesis contrast tests were used in relation to acute kidney injury ...

Introducción: La pandemia por SARS-Cov-2 ha tenido un impacto negativo en múltiples aspectos de la vida humana, tanto en lo físico, psicológico, económico, social y cultural. Las afecciones de la calidad de vida están asociadas al confinamiento y la libertad de salir, de pasar tiempo con sus amigos o familiares, o de realizar actividades; por lo que se ven privados de la mayor parte de su interacción social. El objetivo de este presente artículo es brindar información sobre cómo afecta el confinamiento y aislamiento social por la pandemia a la calidad de vida y salud mental.

Background/Objectives: Endotracheal intubation in critically ill patients presents significant challenges due to anatomical and physiological complexities, making airway management crucial. Video laryngoscopy (VL) has emerged as a promising alternative to direct laryngoscopy (DL), offering improved and higher success rates. This systematic review and meta-analysis evaluated the comparative efficacy and safety of VL versus DL in critically ill adults. Methods: A systematic search was conducted in PubMed, Embase, and Cochrane Library through August 2024 following PRISMA-2020 guidelines. Randomized controlled trials comparing VL and DL in critically ill adult patients were included. The RoB 2.0 tool assessed bias, and GRADE evaluated the certainty of evidence. The primary outcome was first-attempt success; secondary outcomes included intubation time, glottic visualization, and complications...