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artículo

Performance of visual inspection of the cervix with acetic acid (VIA) for triage of HPV screen-positive women: results from the ESTAMPA study

Publicado por
Baena, A, Mesher, D, Salgado, Y, Martínez, S, Villalba, GR, Amarilla, ML, Salgado, B, Flores, B, Bellido-Fuentes, Y, Álvarez-Larraondo, M, Valls, J, Lora, O, Virreira-Prout, G, Figueroa, J, Turcios, E, Soilán, AM, Ortega, M, Celis, M, González, M, Venegas, G, Terán, C, Ferrera, A, Mendoza, L, Kasamatsu, E, Murillo, R, Wiesner, C, Broutet, N, Luciani, S, Herrero, R, Almonte, M

Publicado 2023

Enlace

VIA is recommended for triage of HPV-positive women attending cervical screening. In the multicentric ESTAMPA study, VIA performance for detection of cervical intraepithelial neoplasia grade 3 or worse (CIN3+) among HPV-positive women was evaluated. Women aged 30-64 years were screened with HPV testing and cytology and referred to colposcopy if either test was positive. At colposcopy visit, study-trained midwives/nurses/GPs performed VIA ahead of colposcopy. VIA was considered positive if acetowhite lesions were observed in or close to the transformation zone. Ablative treatment eligibility was assessed for VIA positives. Performance indicators were estimated. Three thousand one hundred and forty-two HPV-positive women were included. Sensitivity for CIN3+ was 85.9% (95% CI 81.2-89.5) among women <50 years and, although not significant, slightly lower in women 50+ (78.0%, 95% CI 65.9-86.6...

artículo

Latin America and the Caribbean Code Against Cancer 1st Edition: Medical interventions including hormone replacement therapy and cancer screening

Publicado por
Baena, A, Paolino, M, Villarreal-Garza, C, Torres, G, Delgado, L, Ruiz, R, Canelo-Aybar, C, Song, Y, Feliu, A, Maza, M, Jeronimo, J, Espina, C, Almonte, M

Publicado 2023

Enlace

Prostate, breast, colorectal, cervical, and lung cancers are the leading cause of cancer in Latin America and the Caribbean (LAC) accounting for nearly 50% of cancer cases and cancer deaths in the region. Following the IARC Code Against Cancer methodology, a group of Latin American experts evaluated the evidence on several medical interventions to reduce cancer incidence and mortality considering the cancer burden in the region. A recommendation to limit the use of HRT was issued based on the risk associated to develop breast, endometrial, and ovarian cancer and on growing concerns related to the over-the-counter and without prescription sales, which in turn bias estimations on current use in LAC. In alignment with WHO breast and cervical cancer initiatives, biennial screening by clinical breast examination (performed by trained health professionals) from the age of 40 years and biennial...