Introduction: Surgical site infections (SSI) can be as high in gynecology and obstetrics surgeries compared to other areas. Antimicrobial prophylaxis is an effective tool in the prevention of SSIs; however, it is often not adequately administered, so this study aimed to understand the compliance and factors associated with the use of the clinical practice guidelines for antibiotic prophylaxis in gynecological surgeries in two hospitals in the city of Huanuco, Peru. Methods: An analytical cross-sectional study of all gynecologic surgeries performed during 2019 was performed. Compliance was determined based on the antibiotic chosen, dose, administration time, redosing, and prophylaxis duration. Age, hospital of origin, presence of comorbidities, surgery performed, as well as its duration, types of surgery, and anesthesia were considered as related factors. Results: We collected 529 medical...

Introduction: Surgical site infections (SSI) can be as high in gynecology and obstetrics surgeries compared to other areas. Antimicrobial prophylaxis is an effective tool in the prevention of SSIs; however, it is often not adequately administered, so this study aimed to understand the compliance and factors associated with the use of the clinical practice guidelines for antibiotic prophylaxis in gynecological surgeries in two hospitals in the city of Huanuco, Peru. Methods: An analytical cross-sectional study of all gynecologic surgeries performed during 2019 was performed. Compliance was determined based on the antibiotic chosen, dose, administration time, redosing, and prophylaxis duration. Age, hospital of origin, presence of comorbidities, surgery performed, as well as its duration, types of surgery, and anesthesia were considered as related factors. Results: We collected 529 medical...

Se estudia el uso de oxacilina en combinación con clindamicina para el tratamiento de infecciones de piel y partes blandas.

El dengue es la enfermedad viral producida por el virus del dengue (DENV), constituida por cuatro serotipos: DENV-1, DENV-2, DENV-3 y DENV-4. Pertenece al género flavivirus, y es transmitido por mosquitos, principalmente por Aedes aegypti. El dengue en la etapa neonatal está pobremente estudiado, con escasos reportes de casos y series pequeñas, tanto de transmisión vertical probada o probable o bien vectorial. Se desconoce la fisiopatología de la enfermedad en este grupo etario, así como si la enfermedad tiene mayor gravedad que en la población adulta. Se presenta el caso de un recién nacido con diagnóstico de dengue.

Con mucho interés hemos leído el artículo especial recientemente publicado en la revista que usted dirige (1) en el cual los autores sugieren el uso de hidroxicloroquina (HC) o cloroquina (CQ) para el tratamiento de casos leves de Covid-19 en la comunidad. Hemos revisado las 39 referencias que citan los autores sin poder encontrar alguna que se refiera al tratamiento de casos leves de Covid-19. La tabla 1 muestra las referencias citadas que son estudios clínicos con HC o CQ en casos moderados/severos de Covid-19. En la carta de Gao (2) se menciona que 100 pacientes de varios ensayos clínicos vienen recibiendo CQ con éxito; sin embargo, esa información preliminar no puede ser corroborada. En la serie de casos de Gautret (3) el 90% de pacientes tratados con HQ presentaron un aclaramiento viral al final del estudio. Hay un reporte de Chen ...

SARS-CoV-2 infection is the most important emerging disease of this century. Since its inception to the present, it has caused almost a million deaths worldwide, becoming a real threat to public health. For this reason, new reviews and scientific studies in this regard are extremely important. In the same way, it is known that the main disease caused by this virus is confined to the respiratory system. However, there are still unknown aspects of the disease and within them are extrapulmonary complications. This review attempts to summarize all that is known at the time regarding the disease and its neurological, hematological, cardiological, kidney and liver complications.

SARS-CoV-2 infection is the most important emerging disease of this century. Since its inception to the present, it has caused almost a million deaths worldwide, becoming a real threat to public health. For this reason, new reviews and scientific studies in this regard are extremely important. In the same way, it is known that the main disease caused by this virus is confined to the respiratory system. However, there are still unknown aspects of the disease and within them are extrapulmonary complications. This review attempts to summarize all that is known at the time regarding the disease and its neurological, hematological, cardiological, kidney and liver complications.

Introduction: In the city of Huánuco and around the world, there is a progressive increase in cases of Tuberculosis and multidrug-resistant Tuberculosis, for this reason it was necessary to identify predictors to develop multidrug-resistant Tuberculosis. Objective: To determine if persistent fever, cavitary radiographic pattern and positive smear microscopy at the first month of treatment, are predictors of multidrug-resistant Tuberculosis in patients with Pulmonary Tuberculosis, in four health facilities in the city of Huánuco, between January 2010 and December 2015. Methods: case and control study. We considered 37 cases and 111 controls. Data were collected from medical records. Results: The predictive factors found in the bivariate analysis were persistence of fever at 2 weeks (p = 0.001, OR 0.05, CI 0.01-0.5), cavitary radiographic pattern (p = 0.000, OR 11.6, 95%IC 4.6-26.5), and...

Introducción: En la ciudad de Huánuco se observa un crecimiento progresivo de casos de Tuberculosis y cada vez más frecuente la Tuberculosis multidrogorresistente, por esta razón fue necesario identificar factores predictores para desarrollar Tuberculosis multidrogorresistente. Objetivo: Determinar si la fiebre persistente, el patrón radiográfico cavitario y la baciloscopía positiva al primer mes de tratamiento son predictores de Tuberculosis multidrogorresistente en pacientes con Tuberculosis Pulmonar en cuatro establecimientos de salud de la ciudad de Huánuco, entre enero 2010 y diciembre 2015. Métodos: Estudio observacional, casos y controles. Se consideraron 37 casos y 111 controles. Los datos se recolectaron de las historias clínicas. Resultados: Los factores predictores encontrados en el análisis bivariado fueron la persistencia de la fiebre a las dos semanas (p=0, 001; ...

Introducción: La tuberculosis multidrogorresistente es un importante problema de salud pública para el que se utilizan fármacos con múltiples efectos adversos. Entre las devastadoras consecuencias de estas enfermedades, existe una amplia variación en la incidencia de ototoxicidad y pérdida auditiva en pacientes con tuberculosis multirresistente y extremadamente resistente. Los implantes cocleares pueden estar indicados en pacientes con pérdida auditiva unilateral/bilateral severa sin beneficio de los audífonos convencionales, pero su uso en pacientes con tuberculosis es raro. Reporte de un caso: Presentamos el primer caso de implante coclear unilateral derecho realizado a un paciente peruano de 34 años que presentaba hipoacusia neurosensorial profunda de origen coclear. Conclusión: La cirugía de implante coclear es un hito fundamental en el tratamiento de los pacientes con sec...

Introduction: Multidrug-resistant tuberculosis is a significant public health problem for which drugs are used with many adverse effects. Among the devastating consequences of these diseases, there is a wide variation in the incidence of ototoxicity and hearing loss in patients with multidrug-resistant and extremely resistant tuberculosis. Cochlear implants may be indicated in patients with unilateral/severe bilateral hearing loss with no benefit from conventional hearing aids, but their use in patients with tuberculosis is rare. Case report: We present the first case of a right unilateral cochlear implant performed on a 34-year-old Peruvian patient who presented profound sensorineural hearing loss of cochlear origin. Conclusion: Cochlear implant surgery is an essential milestone in the treatment of patients with auditory sequelae of tuberculosis treatment. Close monitoring of possible c...

We have recently read the article by Chaung et al1 describing a case of SARS‐CoV‐2 and HCoV‐HKU1 coinfection. The HCoV‐HKU1 is also a member of the Betacoronavirus. In addition to other coronaviruses in different regions of the world, there is an increasing number of reports of coinfections in SARS‐CoV‐2/COVID‐19. Then, we would like to take the opportunity to discuss some of them,1-10 as there are not yet reviews on this emerging issue of COVID‐19. Currently, the evidence suggests that the coinfection rates between SARS‐CoV‐2 and other respiratory pathogens would be higher than initially expected, which represents a challenge for the diagnosis and treatment.

Introduction: Bovine brucellosis is a significant public health problem in countries with economic and zoonotic implications. Although relevant, there are no previous systematic reviews about bovine brucellosis in Latin America. Methods: We performed a systematic literature review in five data-bases to assess the seroprevalence of Brucella in cattle. A meta-analysis with a random-effects model was performed to calculate the pooled prevalence and 95% confidence intervals (95%CI). In addition, measures of heterogeneity (Cochran's Q statistic and I2 test) were reported. Results: The literature search yielded 3,403 articles, of which 65 studies were fully valid for analysis. The pooled seroprevalence for Brucella in bovine (n ​= ​46,883,177) was 4.0% (95%CI: 3.0%–5.0%; p ​< ​0.001), and Venezuela was the country with the highest prevalence (16.0%). By regions, the highest seropreva...

Durante las últimas décadas, el mundo se ha expuesto a una serie de amenazas por brotes virales emergentes de diferente índole, los cuales, sólo al estudiarlos en detalle, surge la posibilidad de comprender su verdadero impacto, no sólo de forma inmediata, si no también, a largo plazo.

Durante las últimas décadas, el mundo se ha expuesto a una serie de amenazas por brotes virales emergentes de diferente índole, los cuales, sólo al estudiarlos en detalle, surge la posibilidad de comprender su verdadero impacto, no sólo de forma inmediata, si no también, a largo plazo. Recientemente, el 12 de diciembre de 2019, la Comisión Municipal de Salud de Wuhan, en la República Popular de China, hizo público un reporte de 27 casos humanos quienes cursaron con una neumonía viral, de los cuales 7 pacientes se encontraban en condiciones críticas, la cual tenía como etiología un nuevo patógeno humano con alta capacidad zoonótica, conocido provisionalmente como Coronavirus novel 2019 (2019-nCoV), y unas semanas después como Enfermedad por Coronavirus 2019 (COVID-19) causada por el virus SARS-CoV-2.

Durante las últimas décadas, el mundo se ha expuesto a una serie de amenazas por brotes virales emergentes de diferente índole, los cuales, sólo al estudiarlos en detalle, surge la posibilidad de comprender su verdadero impacto, no sólo de forma inmediata, si no también, a largo plazo. Recientemente, el 12 de diciembre de 2019, la Comisión Municipal de Salud de Wuhan, en la República Popular de China, hizo público un reporte de 27 casos humanos quienes cursaron con una neumonía viral, de los cuales 7 pacientes se encontraban en condiciones críticas, la cual tenía como etiología un nuevo patógeno humano con alta capacidad zoonótica, conocido provisionalmente como Coronavirus novel 2019 (2019-nCoV), y unas semanas después como Enfermedad por Coronavirus 2019 (COVID-19) causada por el virus SARS-CoV-2.